Lipophilization of somatostatin analog RC-160 with long chain fatty acid improves its anti-proliferative activity on human oral carcinoma cells in vitro

Life Sciences

Volumn 66, Issue 17, 2000, Pages 1557-1570

  Dasgupta, P ^a   Singh, A T ^b   Mukherjee, R ^b  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b DABUR RESEARCH FOUNDATION   (India)

Author keywords

Anti proliferative activity; Lipophilization; Oral carcinoma; Protease resistance; RC 160; Serum resistance; Signaling mechanisms

Indexed keywords

BUTYRIC ACID; CYCLIC AMP; EPIDERMAL GROWTH FACTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LIPOPEPTIDE; LONG CHAIN FATTY ACID; MYRISTIC ACID; OKADAIC ACID; PERTUSSIS TOXIN; PROTEIN TYROSINE KINASE; SOMATOSTATIN 14; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN I 125; SOMATOSTATIN RECEPTOR; TRYPSIN; VANADATE SODIUM; VAPREOTIDE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN KB; CONTROLLED STUDY; DRUG POTENCY; DRUG STABILITY; HUMAN; HUMAN CELL; LIPOPHILICITY; MOUTH CARCINOMA; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS, HORMONAL; BUTYRIC ACID; CELL DIVISION; CYCLIC AMP; FATTY ACIDS; GTP-BINDING PROTEINS; HUMANS; KB CELLS; MOUTH NEOPLASMS; MYRISTIC ACID; PROTEIN-TYROSINE KINASES; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN; TRYPSIN;

EID: 0034677994     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00476-8     Document Type: Article

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