AHR38, a homolog of NGFI-B, inhibits formation of the functional ecdysteroid receptor in the mosquito Aedes aegypti

EMBO Journal

Volumn 19, Issue 2, 2000, Pages 253-262

  Zhu, Jinsong ^a   Miura, Ken ^a,c   Chen, Li ^b   Raikhel, Alexander S ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Mie University ^*  (United States)

^c MIE UNIVERSITY   (Japan)

Author keywords

20 Hydroxyecdysone; AHR38; Mosquito vitellogenesis; Nuclear receptor; Protein protein interaction

Indexed keywords

CELL NUCLEUS RECEPTOR; ECDYSONE RECEPTOR; ECDYSTEROID; ECDYSTERONE; RETINOID X RECEPTOR; STEROID RECEPTOR; UNCLASSIFIED DRUG; YOLK PROTEIN;

AEDES; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA TRANSCRIPTION; FAT BODY; GENE ACTIVATION; GENE ISOLATION; IMMUNOPRECIPITATION; MOSQUITO; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE MATURATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REPORTER GENE; SEQUENCE HOMOLOGY; VITELLOGENESIS;

AEDES AEGYPTI; ARACHNIDA; HEXAPODA; INSECTA;

EID: 0034677199     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.2.253     Document Type: Article

References (47)

1. Beier, J.C. (1998) Malaria parasite development in mosquitoes. Annu. Rev. Entomol., 43, 519-543.
2. Breeden, L. and Nasmyth, K. (1985) Regulation of the yeast HO gene. Cold Spring Harb. Symp. Quant. Biol., 50, 643-650.
3. Bruno, J.-M. et al. (1997) The spirit of Dakar: a call for action on malaria. Nature, 386, 541.
4. Butler, D. (1997) Time to put malaria control on the global agenda. Nature, 386, 535-536.
5. Cho, W.-L., Deitsch, K.W. and Raikhel, A.S. (1991) An extraovarian protein accumulated in mosquito oocytes is a carboxypeptidase activated in embryos. Proc. Natl Acad. Sci. USA, 88, 10821-10824.
6. Cho, W.-L., Kapitskaya, M. and Raikhel, A.S. (1995) Mosquito ecdysteroid receptor: analysis of the cDNA and expression during vitellogenesis. Insect Biochem. Mol. Biol., 25, 19-27.
7. Cho, W.-L., Tsao, S.M., Hays, A.R., Walter, R., Chen, J.S., Snigirevskaya, E.S. and Raikhel, A.S. (1999) Mosquito cathepsin B-like protease involved in embryonic degradation of vitellin is produced as a latent extraovarian precursor. J. Biol. Chem., 274, 13311-13321.
8. Christianson, A.M., King, D.L., Hatzivassiliou, E., Casas, J.E., Hallenbeck, P.L., Nikodem, V.M., Mitsialis, S.A. and Kafatos, F.C. (1992) DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle. Proc. Natl Acad. Sci. USA, 89, 11503-11507.
9. Collins, F.H. and Paskewitz, S.M. (1995) Malaria: current and future prospects for control. Annu. Rev. Entomol., 40, 195-219.
10. Crispi, S., Giordano, E., D'Avino, P.P. and Furia, M. (1998) Cross-talking among Drosophila nuclear receptors at the promiscuous response element of the ng-1 and ng-2 intermolt genes. J. Mol. Biol., 275, 561-574.
11. Deitsch, K.W., Chen, J.S. and Raikhel, A.S. (1995) Indirect control of yolk protein genes by 20-hydroxyecdysone in the fat body of the mosquito, Aedes aegypti. Insect Biochem. Mol. Biol., 25, 449-454.
12. Dhadialla, T.S. and Raikhel, A.S. (1994) Endocrinology of mosquito vitellogenesis. In Davey, K.G., Peter, R.E. and Tobe, S.S. (eds), Perspectives in Comparative Endocrinology. National Research Council of Canada, Ottawa, Canada, pp. 275-281.
13. Dittmann, F., Kogan, P.H. and Hagedorn, H.H. (1989) Ploidy levels and DNA synthesis in the fat body cells of the adult mosquito, Aedes aegypti. Arch. Insect Biochem. Physiol., 12, 133-143.
14. Fallon, A.M., Hagedorn, H.H., Wyatt, G.R. and Laufer, H. (1974) Activation of vitellogenin synthesis in the mosquito Aedes aegypti by ecdysone. J. insect Physiol., 20, 1815-1823.
15. Forman, B.M., Umesono, K., Chen, J. and Evans, R.M. (1995) Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell, 81, 541-550.
16. Glass, C.K. (1994) Differential recognition of target genes by nuclear receptor monomers, dimers and heterodimers. Endocr. Rev., 15, 391-407.
17. Hagedorn, H.H. (1983) The role of ecdysteroids in the adult insect. In Downer, R.G.H. and Laufer, H. (eds), Endocrinology of Insects. Alan R. Liss, New York, NY, pp. 271-304.
18. Hagedorn, H.H. (1985) The role of ecdysteroids in reproduction. In Kerkut, G.A. and Gilbert, L.I. (eds), Comprehensive Insect Physiology, Biochemistry and Pharmacology. Pergamon Press, New York, NY, Vol. 8, pp. 205-261.
19. Hagedorn, H.H. and Fallon, A.M. (1973) Ovarian control of vitellogenin synthesis by the fat body in Aedes aegypti. Nature, 244, 103-105.
20. Hagedorn, H.H., Fallon, A.M. and Laufer, H. (1973) Vitellogenin synthesis by the fat body of Aedes aegypti. Dev. Biol., 31, 285-294.
21. Hagedorn, H.H., O'Connor, J.D., Fuchs, M.S., Sage, B., Schlaeger, D.A. and Bohm, M.K. (1975) The ovary as a source of α-ecdysone in an adult mosquito. Proc. Natl Acad. Sci. USA, 72, 3255-3259.
22. Hays, A.R. and Raikhel, A.S. (1990) A novel protein produced by the vitellogenic fat body and accumulated in mosquito oocytes. Roux's Arch. Dev. Biol., 199, 114-121.
23. Kapitskaya, M., Wang, S.-F., Cress, D.E., Dhadialla, T.S. and Raikhel, A.S. (1996) The mosquito ultraspiracle homologue, a partner of ecdysteroid receptor heterodimer: cloning and characterization of isoforms expressed during vitellogenesis. Mol. Cell. Endocrinol., 121, 119-132.
24. Kastner, P., Mark, M. and Chambon, P. (1995) Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell, 83, 859-869.
25. Kostrouch, Z., Kostrouchova, M. and Rall, J.E. (1995) Steroid/thyroid hormone receptor genes in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA, 92, 156-159.
26. Kozlova, T., Pokholkova, G.V., Tzertzinis, G., Sutherland, J.D., Zhimulev, I.F. and Kafatos, F.C. (1998) Drosophila hormone receptor 38 functions in metamorphosis: a role in adult cuticle formation. Genetics, 149, 1465-1475.
27. Kurokawa, R., DiRenzo, J., Boehm, M., Sugarman, J., Gloss, B., Rosenfeld, M.G., Heyman, R.A. and Glass, C.K. (1994) Regulation of retinoid signaling by receptor polarity and allosteric control of ligand binding. Nature, 371, 528-531.
28. Mangelsdorf, D.J. and Evans, R.M. (1995) The RXR heterodimers and orphan receptors. Cell, 83, 841-850.
29. Mangelsdorf, D.J. et al. (1995) The nuclear receptor superfamily: the second decade. Cell, 83, 835-839.
30. Miura, K., Shinoda, T., Yura, M., Nomura, S., Kamiya, K., Yuda, M. and Chizei, Y. ( 1998) Two hexameric cyanoprotein subunits from an insect, Riptortus clavatus. Sequence, phytogeny and developmental and juvenile hormone regulation. Eur. J. Biochem., 258, 929-940.
31. Miura, K., Wang, S.F. and Raikhel, A.S. (1999) Two distinct subpopulations of ecdysone receptor complex in the female mosquito during vitellogenesis. Mol. Cell. Endocrinol., 156, 111-120.
32. Mori, K., Sant, A., Kohno, K., Normington, K., Gething, M.J. and Sambrook, J.F. (1992) A 22 bp cic-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. EMBO J., 11, 2583-2593.
33. Nuclear Receptors Nomenclature Committee (1999) A unified nomenclature system for the nuclear receptor superfamily. Cell, 97, 161-163.
34. Perlmann, T. and Jansson, L. (1995) A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev., 9, 769-782.
35. Pierceall, W.E., Li, C., Biran, A., Miura, K., Raikhel, A.S. and Segraves, W.A. (1999) E75 expression in mosquito ovary and fat body suggests reiterative use of ecdysone-regulated hierarchies in development and reproduction. Mol. Cell. Endocrinol., 150, 73-89.
36. Raikhel, A.S. (1992) Accumulation of yolk proteins in insect oocytes. Annu. Rev. Entomol., 37, 217-251.
37. Raikhel, A.S. and Lea, A.O. (1990) Juvenile hormone controls previtellogenic proliferation of ribosomal RNA in the mosquito fat body. Gen. Comp. Endocrinol., 77, 423-434.
38. Ribeiro, R.C., Apriletti, J.W., West, B.L., Wagner, R.L., Fletterick, R.J., Schaufele, F. and Baxter, J.D. ( 1993) The molecular biology of thyroid hormone action. Ann. NY Acad. Sci. 758, 366-389.
39. Shapiro, A.B., Wheelock, G.D., Hagedorn, H.H., Baker, F.C., Tsai, L.W. and Schooley, D.A. (1986) Juvenile hormone and juvenile hormone esterase in adult females of the mosquito Aedes aegpti. J. Insect Physiol., 32, 867-877.
40. Sutherland, J.D., Kozlova, T., Tzertzinis, G. and Kafatos, F.C. (1995) Drosophila hormone receptor 38: a second partner for Drosophila USP suggests an unexpected role for nuclear receptors of the nerve growth factor-induced protein B type. Proc. Natl Acad. Sci. USA, 92, 7966-7970.
41. Tsai, M.J. and O'Malley, B.W. (1994) Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem., 63, 451-483.
42. Wang, S.-F., Miura, K., Miksicek, R.J., Segraves, W.A. and Raikhel, A.S. (1998) DNA binding and transactivation characteristics of the mosquito ecdysone receptor-Ultraspiracle complex. J. Biol. Chem., 273, 27531-27540.
43. Wang, S.-F., Li, C., Zhu, J., Miura, K., Miksicek, R.J. and Raikhel, A.S. (2000) Differential expression and regulation by 20-hydroxyecdysone of mosquito ultraspiracle isoforms. Dev. Biol., in press.
44. Wilson, T.E., Fahrner, T.J. and Milbrandt, J. (1993) The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction. Mol. Cell. Biol., 13, 5794-5804.
45. Yao, T.P., Segraves, W.A., Oro, A.E., McKeown, M. and Evans, R.M. (1992) Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell, 71, 63-72.
46. Yao, T.P., Forman, B.M., Jiang, Z., Cherbas, L., Chen, J.D., McKeown, M., Cherbas, P. and Evans, R.M. (1993) Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature, 366, 476-479.
47. Zetterstrom, R.H., Williams, R., Perlmann, T. and Olson, L. (1996) Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system. Mol. Brain Res., 41, 111-120.