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Volumn 2, Issue 23, 2000, Pages 3595-3598

5,6-Diaminocytidine, a versatile synthon for pyrimidine-based bicyclic nucleosides

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIAMINOCYTIDINE; 5,6-DIAMINOCYTIDINE; BICYCLO COMPOUND; CYTIDINE; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PTERIDINE DERIVATIVE; PYRIMIDINE NUCLEOSIDE;

EID: 0034676610     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0064765     Document Type: Article
Times cited : (7)

References (30)
  • 14
    • 0011867745 scopus 로고
    • Townsend, L. B., Ed.; Plenum: New York, (rev), and references cited therein
    • (a) Pfleiderer, F. Chemistry of Nucleosides and Nucleotides; Townsend, L. B., Ed.; Plenum: New York, 1988; Vol. 3 (rev), pp 214-255 and references cited therein.
    • (1988) Chemistry of Nucleosides and Nucleotides , vol.3 , pp. 214-255
    • Pfleiderer, F.1
  • 22
    • 0042801640 scopus 로고    scopus 로고
    • note
    • 12b involving the imino-oxime at the 6- and 5-positions, respectively.
  • 24
    • 85085719920 scopus 로고    scopus 로고
    • note
    • 3 be added to the reaction mixture to force the reactant 4 to react completely to avoid a very difficult Chromatographic separation.
  • 26
    • 0041799373 scopus 로고    scopus 로고
    • note
    • The reaction was performed at 0 and 50°C, but no noticeable change was observed.
  • 27
    • 0041298840 scopus 로고    scopus 로고
    • note
    • The debenzoylation of 8a in methanolic sodium methoxide was very slow and the 5′-mono-O-benzoate of 8a was isolated as a major product. Prolonged treatment of 8a with sodium methoxide in methanol led to partial deglycosylation. The debenzoylation of 9a was complete within 3 h. Details of the successful debenzoylation procedure are provided in the Supporting Information.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.