S-acyl-2-thioethyl aryl phosphotriester derivatives as mononucleotide prodrugs

Journal of Medicinal Chemistry

Volumn 43, Issue 23, 2000, Pages 4570-4574

  Schlienger, N ^a   Peyrottes, S ^a   Kassem, T ^a   Imbach, J L ^a   Gosselin, G ^a   Aubertin, A M ^a,b   Perigaud C ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYL S PIVALOYL 2 THIOETHYL 3' AZIDO 2',3' DIDEOXYTHYMIDIN 5' YL PHOSPHATE; UNCLASSIFIED DRUG; ZIDOVUDINE DERIVATIVE;

AMINO ACID SUBSTITUTION; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL ANALYSIS; DERIVATIZATION; ENZYME ACTIVATION; HUMAN IMMUNODEFICIENCY VIRUS 1; STRUCTURE ANALYSIS; VIRUS REPLICATION;

ANTI-HIV AGENTS; CELL LINE; HIV-1; HYDROLYSIS; PHOSPHORIC ACID ESTERS; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE KINASE; VIRUS REPLICATION; ZIDOVUDINE;

EID: 0034676311     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000996o     Document Type: Article

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