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Volumn 60, Issue 12, 2000, Pages 1933-1935
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Electron paramagnetic resonance spectrometry evidence for bioreduction of tirapazamine to oxidising free radicals under anaerobic conditions
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Author keywords
Bioreduction; EPR; ESR; Free radical; Spin trap; Tirapazamine
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Indexed keywords
1,1',5,5' DIMETHYLPYROLLINE 1 N OXIDE;
ANTINEOPLASTIC AGENT;
CYTOCHROME P450 REDUCTASE;
DIMETHYL SULFOXIDE;
FREE RADICAL;
HYDROXYL RADICAL;
LIVER PROTEIN;
NITROXIDE;
REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;
TIRAPAZAMINE;
UNCLASSIFIED DRUG;
ANAEROBIC METABOLISM;
ANIMAL CELL;
ARTICLE;
CELL HYPOXIA;
CONTROLLED STUDY;
DRUG CYTOTOXICITY;
DRUG METABOLISM;
ELECTRON SPIN RESONANCE;
HUMAN;
HUMAN CELL;
LIVER MICROSOME;
MALE;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
REDUCTION;
SPIN TRAPPING;
ANAEROBIOSIS;
ANIMALS;
ANTINEOPLASTIC AGENTS;
ELECTRON SPIN RESONANCE SPECTROSCOPY;
FREE RADICALS;
MALE;
MICROSOMES, LIVER;
OXIDATION-REDUCTION;
RATS;
RATS, SPRAGUE-DAWLEY;
TIME FACTORS;
TRIAZINES;
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EID: 0034672640
PISSN: 00062952
EISSN: None
Source Type: Journal
DOI: 10.1016/S0006-2952(00)00487-1 Document Type: Article |
Times cited : (28)
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References (7)
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