Inhibitory effect of a novel quinolinone derivative, TA-270, on asthmatic inflammatory responses in sensitized guinea pigs

European Journal of Pharmacology

Volumn 409, Issue 3, 2000, Pages 325-330

  Aoki, Yasuo ^a   Ishiwara, Mitsuteru ^a,b   Koda, Akihide ^c   Takagaki, Hidetsugu ^a  

^a DIC CORPORATION   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Airway hyperresponsiveness; Asthmatic response; Bronchoalveolar eosinophilia; TA 270

Indexed keywords

4 HYDROXY 1 METHYL 3 OCTYLOXY 7 SINAPINOYLAMINO 2(1H) QUINOLINONE; ACETYLCHOLINE; ANTIASTHMATIC AGENT; AZELASTINE; OVALBUMIN; PRANLUKAST; QUINOLINONONE DERIVATIVE; SERATRODAST; TA 270; TRANILAST; UNCLASSIFIED DRUG;

AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CELL INFILTRATION; CONTROLLED STUDY; DOSE RESPONSE; EOSINOPHIL; GUINEA PIG; INFLAMMATORY CELL; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION;

ACETYLCHOLINE; AIRWAY RESISTANCE; ANIMALS; ANTI-ASTHMATIC AGENTS; ANTIOXIDANTS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOCONSTRICTION; CINNAMATES; GUINEA PIGS; INFLAMMATION; MALE; QUINOLONES; VASODILATOR AGENTS;

EID: 0034672612     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00855-4     Document Type: Article

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