Interleukin-2 and interferon-γ double knockout mice reject heterotopic cardiac allografts

Transplantation

Volumn 70, Issue 9, 2000, Pages 1378-1381

  Zand, Martin S ^a,b   Li, Yongsheng ^a   Hancock, Wayne ^c   Li, Xian C ^a   Roy Chaudhury, Prabir ^a   Zheng, Xin Xiao ^a   Strom, Terry B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2;

ALLOGRAFT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DISRUPTION; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034669509     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200011150-00019     Document Type: Article

References (13)

1. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation
2. IL-2 knockout mice reject islet cell allografts
3. T cell regulation in adult transplantation tolerance
4. Acute rejection of vascularized heart allografts in the absence of IFNγ
5. Transfusion of polarized TH2-like cell populations into SCID mouse cardiac allograft recipients results in acute allograft rejection
6. IL-12-deficient mice are defective in IFN-γ production and type 1 cytokine responses
7. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
8. Multiple defects of immune cell function in mice with disrupted interferon-γ genes
9. IL-2 and IL-4 double knockout mice reject islet allografts: A role for novel T cell growth factors in allograft rejection
10. Selective expression of an interleukin-12 receptor component by human T helper 1 cells
11. Type 2 immune deviation has differential effects on alloreactive CD4+ and CD8+ T cells
12. Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
13. Regulation of alloantigen-mediated T-cell proliferation by endogenous interferon-γ: Implications for long-term allograft acceptance