The products of the Drosophila stoned locus interact with synaptic vesicles via synaptotagmin

Journal of Neuroscience

Volumn 20, Issue 22, 2000, Pages 8254-8261

  Phillips, A M ^a   Smith, M ^a   Ramaswami, M ^a   Kelly, L E ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Drosophila melanogaster; Protein interactions; Stoned; Synaptic vesicles; Synaptotagmin

Indexed keywords

DYNAMIN; GLUTATHIONE TRANSFERASE; SYNAPTOTAGMIN;

ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EXOCYTOSIS; GENE MUTATION; NEUROMUSCULAR SYNAPSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SYNAPSE VESICLE;

DROSOPHILA; DROSOPHILA MELANOGASTER;

EID: 0034668912     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-22-08254.2000     Document Type: Article

References (46)

1. The stoned locus of Drosophila melanogaster produces a dicistronic transcript and encodes two distinct polypeptides
2. Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster
3. Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis
4. Postsynaptic PKA controls quantal size and reveals a retrograde signal that regulates presynaptic transmitter release in Drosophila
5. 2+/phospholipid binding
6. The effect on synaptic physiology of synaptotagmin mutations in Drosophila
7. Synaptic transmission persists in synaptotagmin mutants of Drosophila
8. The stoned proteins regulate synaptic vesicle recycling in the presynaptic terminal
9. Role of the C2B domain of synaptotagmin in vesicle release and recycling as determined by specific antibody injection into the squid giant synapse preterminal
10. Role of Drosophila α-adaptin in presynaptic vesicle recycling
11. Temperature-sensitive mutations in Drosophila melanogaster. XIV. A selection of immobile adults
12. Immunoaffinity purification
13. Some mutations affecting neural or muscular tissues alter the physiological components of the electroretinogram in Drosophila
14. Behavioral mutants of Drosophila melanogaster. I. Isolation and mapping of mutations which decrease flight ability
15. Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans
16. An altered electroretinogram transient associated with an unusual jump response in a mutant of Drosophila
17. Identification of a gene family from Drosophila melanogaster encoding proteins with homology to invertebrate sarcoplasmic calcium-binding proteins
18. Adaptors for clathrin-mediated traffic
19. Synaptic vesicles have two distinct recycling pathways
20. Two distinct pools of synaptic vesicles in single presynaptic boutons in a temperature-sensitive Drosophila mutant, shibire
21. 2+-dependent and -independent activities of neural and non-neural synaptotagmins
22. 2+-activated neurotransmitter release
23. Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse
24. Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants
25. Synaptic function modulated by changes in the ratio of synaptotagmin I and IV
26. Reversible inhibition of endocytosis in cultured neurons from the Drosophila temperature-sensitive mutant shibre(ts1)
27. Localization of the genes Shaking-B, small optic lobes, sluggish-A, stoned and stress sensitive-C to a well-defined region on the X-chromosome of Drosophila melanogaster
28. Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin
29. A structural explanation for the binding of multiple ligands by the α-adaptin appendage domain
30. Vesicle recycling revisited: Rapid endocytosis may be the first step
31. A genetic analysis of the stoned locus and its interaction with dunce, shibire and Suppressor of stoned variants of Drosophila melanogaster
32. Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila
33. The role of clathrin, adaptors and dynamin in endocytosis
34. DNA sequencing with chain termination inhibitors
35. A product of the Drosophila stoned genetic locus regulates neurotransmitter release
36. Synaptotagmins: C2-domain proteins that regulate membrane traffic
37. 2+-dependent properties of the first and second C2-domains of synaptotagmin 1
38. Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals
39. Molecular cloning and complete amino acid sequence of AP50, an assembly protein associated with clathrin-coated vesicles
40. The regulation of endocytosis: Identifying dynamin's binding partners
41. Redistribution of synaptic vesicles and their proteins in temperature-sensitive shibire(ts1) mutant Drosophila
42. Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic
43. Synaptic vesicles are regulated by a clathrin adaptor protein required for endocytosis
44. Synaptotagmin 1 is a high affinity receptor for clathrin AP-2: Implications for membrane recycling
45. Altered synaptic plasticity in Drosophila memory mutants with a defective cyclic AMP cascade