Novel mechanism of antibody-independent complement neutralization of herpes simplex virus type 1

Journal of Immunology

Volumn 165, Issue 8, 2000, Pages 4528-4536

  Friedman, H M ^a   Wang, L ^a   Pangburn, M K ^a   Lambris, J D ^a   Lubinski, J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C8; GLYCOPROTEIN;

ARTICLE; BINDING AFFINITY; GENE EXPRESSION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; VIRUS ENVELOPE; VIRUS REPLICATION;

EID: 0034667942     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.8.4528     Document Type: Article

References (57)

1. Antibody mediated complement dependent lysis of virus infected cells
2. Complement, viruses, and virus-infected cells
3. Complement-mediated phagocytosis of herpes simplex virus by granulocytes: Binding or ingestion
4. Attachment of human polymorphonuclear leukocytes to herpes simplex virus-infected fibroblasts mediated by antibody-independent complement activation
5. Complement-dependent polymorphonuclear neutrophil-mediated cytotoxicity of herpesvirus-infected cells: Possible mechanism(s) of cytotoxicity
6. Complement and the immune response
7. The role of complement and complement receptors in induction and regulation of immunity
8. Protective T cell-independent antiviral antibody responses are dependent on complement
9. Humoral response to herpes simplex virus is complement-dependent
10. Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component in infected cells
11. Complement component C3b binds directly to purified glycoprotein C of herpes simplex virus types 1 and 2
12. Species selective interaction of alphaherpesvirinae with the 'unspecific' immune system of the host
13. gp13 (EHV-gC): A complement receptor induced by equine herpesviruses
14. Glycoprotein C of herpes simplex virus 1 is an inhibitor of the complement cascade
15. The interaction of glycoprotein C of herpes simplex virus types 1 and 2 with the alternative complement pathway
16. Mechanism of complement inactivation by glycoprotein C of herpes simplex virus
17. Immune evasion properties of herpes simplex virus type 1 glycoprotein gC
18. Herpes simplex virus glycoproteins gC-1 and gC-2 bind to the third component of complement and provide protection against complement-mediated neutralization of viral infectivity
19. Glycoprotein C of herpes simplex virus type 1 prevents complement-mediated cell lysis and virus neutralization
20. Herpes simplex virus type 1 glycoprotein gC mediates immune evasion in vivo
21. In vivo role of complement-interacting domains of herpes simplex virus type 1 glycoprotein gC
22. Inhibition of the complement cascade by the major secretory protein of vaccinia virus
23. Vaccinia virus complement-control protein prevents antibody-dependent complement-enhanced neutralization of infectivity and contributes to virulence
24. Interaction of vaccinia virus complement control protein with human complement proteins: Factor I-mediated degradation of C3b to iC3b(i) inactivates the alternative complement pathway
25. Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope
26. Complement control proteins, CD46, CD55, and CD59, as common surface constituents of human immunodeficiency viruses and possible targets for vaccine protection
27. Human immunodeficiency virus type 1 incorporates both glycosyl phosphatidylinositol-anchored CD55 and CD59 and integral membrane protein CD46 at levels that protect from complement-mediated destruction
28. Role of complement in HIV infection
29. Neutralization of cytomegalovirus virions: The role of complement
30. Lysis of oncornaviruses by human serum: Isolation of the viral component (C1) receptor and identification of p15E
31. Human immunodeficiency virus type 1 activates the classical pathway of complement by direct C1 binding through specific sites in the transmembrane glycoprotein gp41
32. Human serum lyses RNA tumor viruses
33. Human T-cell leukemia virus is not lysed by human serum
34. CR1 (CD35) and CR3 (CD11b/CD18) mediate infection of human monocytes and monocytic cell lines with complement-opsonized HIV independently of CD4
35. A novel mechanism of retrovirus inactivation in human serum mediated by anti-α-galactosyl natural antibody
36. Sensitization of cells and retroviruses to human serum by (α1-3) galactosyltransferase
37. Evaluation of the Galα1-3Gal epitopes as a host modification factor eliciting natural humoral immunity to enveloped viruses
38. Neutralization of vesicular stomatitis virus (VSV) by human complement requires a natural IgM antibody present in human serum
39. Host cell modification of lymphocytic choriomeningitis virus and Newcastle disease virus altering viral inactivation by human complement
40. In vivo immune evasion mediated by the herpes simplex virus type 1 immunoglobulin G Fc receptor
41. Microassay for colorimetric estimation of complement activity in guinea pig, human and mouse serum
42. Immunoelectron microscopy in diagnostic virology
43. Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry
44. Transmembrane channel formation by complement: Functional analysis of the number of C5b6, C7, C8 and C9 molecules required for a single channel
45. Complement component C8γ is expressed in human fetal and adult kidney independent of C8α
46. Inactivation and lysis of oncornaviruses by human serum
47. Complement-dependent mechanisms of virus neutralization
48. Antibody-independent neutralization of vesicular stomatitis virus by human complement. I. Complement requirements
49. Host modification of sindbis virus sialic acid content influences alternative complement pathway activation and virus clearance
50. Neutralization of Epstein-Barr virus by nonimmune human serum: Role of cross-reacting antibody to herpes simplex virus and complement
51. Binding of complement component C3b to glycoprotein gC of herpes simplex virus type 1: Mapping of gC-binding sites and demonstration of conserved C3b binding in low-passage clinical isolates
52. Serologic analysis of herpes simplex virus types 1 and 2 with monoclonal antibodies
53. Characterization of glycoprotein C-negative mutants of herpes simplex virus type 1 isolated from a patient with keratitis
54. Cell fusion induced by herpes simplex virus is promoted and suppressed by different viral glycoproteins
55. Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity
56. Initial interaction of herpes simplex virus with cells is binding to heparan sulfate
57. Potentiation of C1 inhibitor by glycosaminoglycans: Dextran sulfate species are effective inhibitors of in vitro complement activation in plasma