Phase I trial of 6-hour infusion of glufosfamide, a new alkylating agent with potentially enhanced selectivity for tumors that overexpress transmembrane glucose transporters: A study of the European Organization for Research and Treatment of Cancer Early Clinical Studies Group

Journal of Clinical Oncology

Volumn 18, Issue 20, 2000, Pages 3535-3544

  Briasoulis, Evangelos ^a   Judson, Ian ^a   Pavlidis, Nicholas ^a   Beale, Philip ^a   Wanders, Jantien ^a   Groot, Yvonne ^a   Veerman, Gijbert ^a   Schuessler, Martina ^a   Niebch, Georg ^a   Siamopoulos, Konstantinos ^a   Tzamakou, Eleftheria ^a   Rammou, Dimitra ^a   Wolf, Lisa ^a   Walker, Ruth ^a   Hanauske, Axel ^a  

^a UNIVERSITY OF IOANNINA   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; BETA DEXTRO GLUCOPYRANOSYL N,N' BIS(2 CHLOROETHYL)PHOSPHORIC ACID DIAMIDE; GLUCOSE TRANSPORTER; GLUFOSFAMIDE; UNCLASSIFIED DRUG;

ADULT; AGED; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; DRUG SELECTIVITY; FEMALE; HUMAN; HYPOKALEMIA; HYPOPHOSPHATEMIA; KIDNEY TUBULE ACIDOSIS; MALE; MAXIMUM PERMISSIBLE DOSE; METABOLIC ACIDOSIS; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SOLID TUMOR;

EID: 0034667838     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2000.18.20.3535     Document Type: Article

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