Pharmacokinetics and whole body distribution of the new chemotherapeutic agent β-D-glucosylisophosphoramide mustard and its effects on the incorporation of [methyl-3H]-thymidine in various tissues of the rat

Cancer Chemotherapy and Pharmacology

Volumn 38, Issue 4, 1996, Pages 355-365

  Stüben, Jörg ^a   Port, Rüdiger ^a   Bertram, Barbara ^a   Bollow, Ursula ^a   Hull, William E ^a   Schaper, Marianne ^a   Pohl, Jörg ^b   Wiessler, Manfred ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b ASTA MEDICA AG   (Germany)

Author keywords

D Glucosylisophosphoramide mustard; Pharmacokinetics; Plasma protein binding; Whole body autoradiography

Indexed keywords

PHOSPHORIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; AUTORADIOGRAPHY; BILIARY EXCRETION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTORADIOGRAPHY; BILE; DNA, NEOPLASM; FEMALE; GLUCOSE; HALF-LIFE; HUMANS; IFOSFAMIDE; MALE; METABOLIC CLEARANCE RATE; PROSTATIC NEOPLASMS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN; STEREOISOMERISM; THYMIDINE; TISSUE DISTRIBUTION; TRITIUM;

EID: 0029679705     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050495     Document Type: Article

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