Expression of a cDNA encoding a Toxoplasma gondii protein belonging to the heat-shock 90 family and analysis of its antigenicity

FEMS Microbiology Letters

Volumn 190, Issue 2, 2000, Pages 209-213

  Rojas, Paola A ^a   Martin, Valentina ^a   Nigro, Mónica ^a   Echeverria, Pablo C ^a   Guarnera, Eduardo A ^a   Pszenny, Viviana ^a   Angel, Sergio O ^a  

^a Inst Nac Parasitol Dr Mario F   (Argentina)

Author keywords

cDNA; Heat shock protein 90; Humoral response; Toxoplasma gondii

Indexed keywords

COMPLEMENTARY DNA; HEAT SHOCK PROTEIN 90;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ANTIGENICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; HUMAN; HUMAN TISSUE; HUMORAL IMMUNITY; IMMUNOGENICITY; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, PROTOZOAN; BLOTTING, WESTERN; DNA, COMPLEMENTARY; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; TOXOPLASMA; TOXOPLASMOSIS; TOXOPLASMOSIS, ANIMAL;

ANIMALIA; PROTOZOA; TOXOPLASMA GONDII;

EID: 0034666554     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(00)00337-2     Document Type: Article

References (14)

1. Shinnick T.M. Heat shock proteins as antigens of bacterial and parasitic pathogens. Curr. Top. Microbiol. Immunol. 167:1991;145-160.
2. Matthews R., Burnie J. The role of hsp90 in fungal infection. Immunol. Today. 13:1992;345-348.
3. Angel S.O., Requena J.M., Soto M., Criado D., Alonso C. During canine leishmaniasis a protein belonging to the 83-k heat shock protein family elicits a strong humoral response. Acta Trop. 62:1996;45-56.
4. Bonnefoy S., Gysin J., Blisnick T., Guillote M., Carcy B., Pereira da Silva L., Mercereau-Puijalon O. Immunogenicity and antigenicity of a Plasmodium falciparum protein fraction (90-110-kDa) able to protect squirrel monkeys against asexual blood stages. Vaccine. 12:1994;32-40.
5. Rico A.I., Angel S.O., Alonso C., Requena J.M. Immunostimulatory properties of the Leishmania infantum Heat shock proteins HSP70 and HSP83. Mol. Immunol. 36:1999;1131-1139.
6. Alexander J., Jebbari H., Bluethmann H., Satoskar A., Roberts C.W. Immunological control of Toxoplasma gondii vaccine design. Curr. Top. Microbiol. Immunol. 219:1996;183-195.
7. Ajioka J.W., Boothroyd J.C., Brunk B.P., Hehl A., Hillier L., Manger I.D., Marra M., Overton G.C., Roos D.S., Wan K.I., Waterston R., Sibley L.D. Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the apicomplexa. Genom. Res. 8:1998;18-28.
8. Martín V., Arcavi M., Amendoeira M.R.R., de Souza Neves E., Santillán G., Guarnera E., Garberi J.C., Angel S.O. Detection of human anti-Toxoplasma specific immunioglobulins A, M and G by a recombinant Toxoplasma gondii Rop2 protein. Clin. Diagn. Lab. Immunol. 5:1998;627-631.
9. Bonnefoy S., Attal G., Langsley G., Tekaia F., Mercereau-Puijalon O. Molecular characterization of the heat shock protein 90 gene of the human malaria parasite Plasmodium falciparum. Mol. Biochem. Parasitol. 67:1994;157-170.
10. Mun H.S., Aosai F., Yano A. Role of Toxoplasma gondii HSP70 and Toxoplasma gondii HSP30/bag1 in antibody formation and prophylatic immunity in mice experimentally infected with Toxoplasma gondii. Microbiol. Immunol. 43:1999;471-479.
11. Weiss L.M., Ma Y.F., Takvorian P.M., Tanowitz H.B., Wittner M. Bradyzoite development in Toxoplasma gondii and the hsp70 stress response. Infect. Immun. 66:1998;3295-3302.
12. Silva N.M., Gazzinelli R.T., Silva D.A.O., Ferro E.A., Kasper L.H., Mineo J.R. Expression of Toxoplasma gondii-specific heat shock protein 70 during in vivo conversion of bradyzoites to tachyzoites. Infect. Immun. 66:1998;3959-3963.
13. Clark T.G., Abrahamsen M.S., White M.W. Developmental expression of heat shock protein 90 in Eimeria bovis. Mol. Biochem. Parasitol. 78:1996;259-263.
14. Zhang M., Hisaeda H., Tsuboi T., Torii T., Sakai T., Nakano Y., Ishikawa H., Maekawa Y., Good R.A., Himeno K. Stage-specific expression of heat shock protein 90 in murine malaria parasite Plasmodium yoelii. Exp. Parasitol. 93:1999;61-65.