Effects of combined administration of zonisamide and valproic acid or phenytoin to nitric oxide production, monoamines and zonisamide concentrations in the brain of seizure-susceptible EL mice

Brain Research Bulletin

Volumn 53, Issue 2, 2000, Pages 211-218

  Nagatomo, Itsugi ^a   Akasaki, Yasuaki ^a   Uchida, Masahiro ^a   Tominaga, Masataka ^a   Hashiguchi, Wataru ^a   Takigawa, Morikuni ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

EL mouse; Monoamine; Nitric oxide; Phenytoin; Valproic acid; Zonisamide

Indexed keywords

BRAIN MONOAMINE; MONOAMINE; NITRIC OXIDE; PHENYTOIN; VALPROIC ACID; ZONISAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BRAIN LEVEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ANIMAL; ANTICONVULSANTS; BIOGENIC MONOAMINES; BRAIN; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; EPILEPSY; ISOXAZOLES; MICE; MICE, MUTANT STRAINS; NITRIC OXIDE; PHENYTOIN; VALPROIC ACID;

EID: 0034665587     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(00)00333-6     Document Type: Article

References (56)

1. The effect of phenobarbital on the multiple neuronal activity in the hippocampus of El mouse
2. Metabolism and anticonvulsant properties of pridone in rats
3. Nitric oxide; An endogenus anticonvulsant substance
4. Acute, chronic and differential effects of several anesthetic barbiturates on glutamate receptor activation in neuronal culture
5. Spontaneous recurrent seizures in rats; Amino acid and monoamine determination in the hippocampus
6. Blood-brain barrier transport of CI-912; Single-passage equilibration of erythrocyte-borne drug
7. Experimental animal epilepsy; A new device for the induction of epileptic seizures in the murine. El mouse
8. Endothelium-derived relaxing factor release on activation of NMDA receptors suggestes role as intercellular messenger in the brain
9. Glutamate, nitric oxide and cell-cell signalling in the nervous system
10. Link between catecholamine and nitric oxide metabolism
11. Application of automated flow injection analysis to determine nitrite and nitrate in mouse brain
12. Role of nitric oxide in NMDA-evoked release of [3H]-dopmaine from striatal slices
13. General pharmacology of the novel antiepileptic compound zonisamide
14. Mutant stocks, strain El
15. Role of noradrenergic system in the seizures of El mouse
16. Inhibition of long-term potentiation by NMDA-mediated nitric oxide release
17. Involvement of nitric oxide and nitric oxide synthase activity in anticonvulsive action
18. Chronic administration of citalopram inhibited EL mouse convulsions and decreased monoamine oxidase-A activity
19. Reduction in nitric oxide synthase activity with development of an epileptogenesis focus induced by ferric chloride in the rat brain
20. Carbamazepine and zonisamide increase extracelluar dopamine and serotonin levels in vivo, and carbamazepine does not antagonize adenosine effect in vitro; Mechanisms of blockade of seizure spread
21. Pharmacokinetic interaction of zonisamide in rats. Effects of other antiepileptics on zonisamide
22. Pharmacokinetic interaction of zonisamide in rats. Effects of zonisamide on other antiepileptics
23. Anticonvulsant effects of opioid agonists in the seizure-susceptible El mouse
24. Metabolic studies on ep mouse, a special strain with convulsive predisposition
25. Prospectes for clinically tolerated NMDA antagonists; Open-channel blockers and alternative redox states of nitric oxide
26. Inhibition by lamotrigine of the generation of nitric oxide in rats forebrain slices
27. 3-sulfamoylmethyl-1, 2-benzisoxazol, a new type of anticonvulsant drug
28. Binding of sulfonamide to erythrocyte proteins and possible drug-drug interaction
29. Pharmacology of GABA
30. Effect of chronic administration of phenytoin on regional monoamine levels in rat brain
31. Lamotrigine
32. Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex
33. Relationships between convulsive seizures and serum and brain concentrations of phenobarbital and zonisamide in mutant inbred EL mouse
34. Sparse distribution of NADPH diaphorase neurons in the hippocampal formation of the inbred mutant strain EL mouse
35. Pharmacokinetics of zonisamide; Saturable distribution into human and rat erythrocytes and into rat brain
36. Behavioral sensitization and relative hyperresponsiveness of striatal and limbic dopaminergic neurons after repeated methamphetamine treatment
37. Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy
38. 2+ dependent dopamine release
39. Inhibition of NO synthase increases the severity of kainic acid-induced seizures in rodents
40. Multicenter study on the efficacy on zonisamide in the treatment of medically refractory complex partial seizures
41. Blockade of sustained repetitive action potentials in culture spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant
42. Pilot study of zonisamide (1, 2-benzisoxazol-3-methane-sulfonamide) in patients with refractory partial seizures
43. Zonisamide enhances slow sodium inactivation in Myxicola
44. Zonisamide
45. Inherited convulsive disorders in mice
46. Changes in learning and memory, acetylcholinesterase activity and monoamines in brain after chronic carbamazepine administration in rats
47. Efficacy of zonisamide in children with refractory partial seizures
48. Seizures patterns and electroencephalograms of El mouse
49. Sensory precipitating epileptic focus in El mice and Mongolian geribils
50. Changes in glutamate receptors, c-fos mRNA expression and activator protein-1 (AP-1) DNA binding activity in the brain of phenobarbital-dependent and -withdrawn rats
51. Drug interactions of zonisamide with phenytoin and sodium valproate; Serum concentrations and protein binding
52. Nitric oxide production is decreased in the brain of the seizure susceptible EL mouse
53. Pharmacokinetics of CI-912 in epileptic patients
54. Zonisamide in epilepsy. A pilot study
55. Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain
56. Effect of nitroprusside (nitric oxide) on endogenous dopamine release from rat striatal slices