Kinetic and structural analysis of the ultrasensitive behaviour of cyanobacterial adp-glucose pyrophosphorylase

Biochemical Journal

Volumn 350, Issue 1, 2000, Pages 139-147

  Casati, D F G ^a   Aon, M A ^a   Iglesias, A A ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Anabaena PCC 7120; Enzyme structure and regulation; Glycogen and starch biosynthesis; Molecular crowding; Ultrasensitivity

Indexed keywords

GLUCOSE 1 PHOSPHATE; GLUCOSE 1 PHOSPHATE ADENYLYLTRANSFERASE; GLYCOGEN; POLYSACCHARIDE;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CYANOBACTERIUM; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME STRUCTURE; GLYCOGEN SYNTHESIS; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; CHROMATOGRAPHY, GEL; CYANOBACTERIA; ENZYME ACTIVATION; GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE; KINETICS; NUCLEOTIDYLTRANSFERASES; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE;

ANABAENA; CYANOBACTERIA; NOSTOC SP. PCC 7120;

EID: 0034663476     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3500139     Document Type: Article

References (36)

1. Starch biosynthesis and its regulation
2. Bacterial glycogen and plant starch biosynthesis
3. Complexes of sequential metabolic enzymes
4. Macromolecular crowding and confinement in cells exposed to hypertonicity
5. The high concentrations ofenzymes within the chloroplast
6. The effect of volume occupancy upon the thermodynamic activity of proteins: Some biochemical consequences
7. Macromolecular crowding: Biochemical, biophysical consequences
8. Dynamic Biological Organization
9. Molecular crowding and cytoskeletal proteins affect the allosteric regulatory properties of ADPglucose pyrophosphorylase
10. Ultrasensitive glycogen synthesis in cyanobacteria
11. Effect of macromolecular crowding upon the structure and function of an enzyme: Glyceraldehyde-3-phosphate dehydrogenase
12. Molecular crowding: Analysis of effects of high concentration of inert cosolutes on biochemical equilibria and rates in terms of volume exclusion
13. Effect of poly(ethylene glycol) on the activity, intrinsic fluorescence and oligomeric structure of castor seed cytosolic fructose-1,6-bisphosphatase
14. Solvent effects on protein stability
15. Amplification and adaptation in regulatory and sensory systems
16. Sensitivity amplification in biochemical systems
17. Switches, thresholds and ultrasensitivity
18. The era of pathway quantification
19. Molecular cloning and expression of the gene encoding ADPglucose pyrophosphorylase from the cyanobacterium Anabaena sp. strain PCC 7120
20. Structure-function relationships of cyanobacterial ADPglucose pyrophosphorylase: Site-directed mutagenesis and chemical modification of the activator-binding sites of ADPgtucose pyrophosphorylase from Anabaena PCC 7120
21. Adenosine diphosphate glucose pyrophosphorylase: A regulatory enzyme in the biosynthesis of starch in spinach chloroplast
22. A simple computer program with statistical tests for analysis of enzyme kinetics
23. A simplification of the protein assay method of Lowry et al. which is more generally applicable
24. Fourth-derivative spectrophotometry of proteins
25. Transmission of regulatory conformational changes through proteins
26. pH-induced bistable dynamic behaviour in the reaction catalysed by glucose-6-phosphate dehydrogenase and conformational hysteresis of the enzyme
27. Fluorescence and the location of tryptophan residues in protein molecules
28. Fourth-derivative spectrophotometry analysis of tryptophan environment in proteins: Application to mellitin, cytochrome c and bacteriorhodopsin
29. Regulation of the amount of starch in plant tissues by ADPglucose pyrophosphorylase
30. Starch, sucrose biosynthesis and partition of carbon in plants are regulated by orthophosphate and triose-phosphates
31. Metabolic organization and the ultrastructure of animal cells
32. Microtubular protein in its polymerized or non-polymerized states differentially modulates in vitro and intracellular fluxes catalysed by enzymes related to carbon metabolism
33. Effects of stress on cellular infrastructure and metabolic organization in plant cells
34. Molecular crowding and viscosity as determinants of translational diffusion of metabolites in subcellular organelles