Use of echinacea in medicine

Biochemical Pharmacology

Volumn 60, Issue 2, 2000, Pages 155-158

  Percival, Susan S ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Dietary supplement; Echinacea; Herbal medicine; Immunomodulating herbs

Indexed keywords

BRONCHITIS; CLINICAL TRIAL; COMMON COLD; COUGHING; DIET SUPPLEMENTATION; DISEASE SEVERITY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG INDICATION; DRUG MECHANISM; DRUG SAFETY; ECHINACEA; GERMANY; HERBAL MEDICINE; HUMAN; IMMUNE SYSTEM; IMMUNOMODULATION; INFLAMMATION; MEDICAL RESEARCH; NONHUMAN; PHAGOCYTOSIS; PLANT LEAF; PLANT ROOT; PRIORITY JOURNAL; SHORT SURVEY; UPPER RESPIRATORY TRACT INFECTION;

ECHINACEA;

EID: 0034662430     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00413-X     Document Type: Article

References (26)

1. Barrett B., Kiefer D., Rabago D. Assessing the risks and benefits of herbal medicine An overview of scientific evidence . Altern Ther. 5:1999;40-49.
2. Dietary Supplement Health and Education Act, 103-417, 3.(a). 1994 Bill/Resolution.
3. Gruenwald J., Brendler T., Jaenicke C., PDR for Herbal Medicines. 1998;Medical Economics Co, Montvale, NJ.
4. Graisbauer M., Scheleich T., Stickl H.A., Wilczek I. The effect of echinacea purpurea Moench on phagocytosis in granulocytes measured by chemiluminescence. (In German.). Arzneimittelforschung. 40:1990;594-598.
5. Blumenthal M., The Complete German Commission E Monographs, Therapeutic Guide to Herbal Medicines. 1998;American Botanical Council, Austin.
6. Facino R.M., Carini M., Aldini G., Saibene L., Pietta P., Mauri P. Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation A potential use of Echinacea extracts in the prevention of skin photodamage . Planta Med. 61:1995;510-514.
7. Muller-Jakic B., Breu W., Probstle A., Redl K., Greger H., Bauer R. In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species. Planta Med. 60:1994;37-40.
8. Tragni E., Tubaro A., Melis S., Galli C.L. Evidence from two classic irritation tests for an anti-inflammatory action of a natural extract, Echinacina B. Food Chem Toxicol. 23:1985;317-319.
9. Tubaro A., Tragni E., Del Negro P., Galli C.L., Della Loggia R. Anti-inflammatory activity of a polysaccharide fraction of Echinacea angustifolia. J Pharm Pharmacol. 39:1987;567-569.
10. Tragni E., Galli C.L., Tubaro A., Del Negro P., Della Loggia R. Anti-inflammatory activity of Echinacea angustifolia fractions separated on the basis of molecular weight. Pharmacol Res Commun. 20:(Suppl V):1988;87-90.
11. Wagner H., Stuppner H., Schafer W., Zenk M. Immunologically active polysaccharides of Echinacea purpurea cell cultures. Phytochemistry. 27:1988;119-126.
12. Luettig B., Steinmüller C., Gifford G.E., Wagner H., Lohmann-Matthes M.-L. Macrophage activation by the polysaccharide arabinogalactan isolated from plant cell cultures of Echinacea purpurea. J Natl Cancer Inst. 81:1989;669-675.
13. Stimpel M., Proksch A., Wagner H., Lohmann-Matthes M.-L. Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea. Infect Immun. 46:1984;845-849.
14. Burger R.A., Torres A.R., Warren R.P., Caldwell V.D., Hughes B.G. Echinacea-induced cytokine production by human macrophages. Int J Immunopharmacol. 19:1997;371-379.
15. Roesler J., Steinmüller C., Kiderlen A., Emmendörffer A., Wagner H., Lohmann-Matthes M.-L. Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to mice mediates protection against systemic infections with Listeria monocytogenes and Candida albicans. Int J Immunopharmacol. 13:1991;27-37.
16. Steinmüller C., Roesler J., Gröttrup E., Franke G., Wagner H., Lohmann-Matthes M.-L. Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes. Int J Immunopharmacol. 15:1993;605-614.
17. Roesler J., Emmendörffer A., Steinmüller C., Luettig B., Wagner H., Lohmann-Matthes M.-L. Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to test subjects mediates activation of the phagocyte system. Int J Immunopharmacol. 13:1991;931-941.
18. See D.M., Broumand N., Sahl L., Tilles J.G. In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients. Immunopharmacology. 35:1997;229-235.
19. Groman E.V., Gou D. Development of an immunoassay for larch arabinogalactan and its use in the detection of larch arabinogalactan in rat blood. Carbohydr Res. 301:1997;69-76.
20. Puhlman J., Zenk M.H., Wagner H. Immunologically active polysaccharides of Arnica montana cell cultures. Phytochemistry. 30:1991;1141-1145.
21. Lersch C., Zeuner M., Bauer A., Siemens M., Hart R., Drescher M., Fink U., Dancygier H., Classen M. Nonspecific immunostimulation with low doses of cyclophosphamide (LDCY), thymostimulin and Echinacea purpurea extracts (Echinacin) in patients with far advanced colorectal cancers Preliminary results . Cancer Invest. 10:1992;343-348.
22. Lersch C., Zeuner M., Bauer A., Siebenrock K., Hart R., Wagner F., Fink U., Dancygier H., Classen M. Stimulation of the immune response in outpatients with hepatocellular carcinomas by low doses of cyclophosphamide (LDCY), echinacea purpurea extracts (Echinacin) and thymostimulin. Arch Geschwulstforsch. 60:1990;379-383.
23. Melchart D., Linde K., Worku F., Sarkady L., Holzmann M., Jurcic K., Wagner H. Results of five randomized studies on the immunomodulatory activity of preparations of Echinacea. J Alt Comp Med. 1:1995;145-160.
24. Melchart D., Walther E., Linde K., Brandmaier R., Lersch C. Echinacea root extracts for the prevention of upper respiratory tract infections A double-blind, placebo controlled randomized trial . Arch Fam Med. 7:1998;541-545.
25. Grimm W., Müller H.-H. A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds and respiratory infections. Am J Med. 106:1999;138-143.
26. Chamberlain C, Take Echinacea? Bless you, Popular herb may make colds worse. http://abcnews.go.com/sections/living/DailyNews/echinacea990427.html.