메뉴 건너뛰기




Volumn 348, Issue 3, 2000, Pages 497-506

Auto-catalysed progression of aneuploidy explains the Hayflick limit of cultured cells, carcinogen-induced tumours in mice, and the age distribution of human cancer

Author keywords

Carcinogenesis; Dynamics; Metabolic control analysis

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; DNA;

EID: 0034660135     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3480497     Document Type: Article
Times cited : (11)

References (51)
  • 1
    • 0032506125 scopus 로고    scopus 로고
    • Genetic instability of cancer cells is proportional to their degree of aneuploidy
    • 1 Duesberg, P., Rausch, C., Rasnick, D. and Hehlmann, R. (1998) Genetic instability of cancer cells is proportional to their degree of aneuploidy. Proc. Natl. Acad. Sci. U.S.A. 95, 13692-13697
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 13692-13697
    • Duesberg, P.1    Rausch, C.2    Rasnick, D.3    Hehlmann, R.4
  • 3
    • 0033564230 scopus 로고    scopus 로고
    • How aneuploidy affects metabolic control and causes cancer
    • 3 Rasnick, D. and Duesberg, P. H. (1999) How aneuploidy affects metabolic control and causes cancer. Biochem. J 340, 621-630
    • (1999) Biochem. J , vol.340 , pp. 621-630
    • Rasnick, D.1    Duesberg, P.H.2
  • 6
    • 0003240078 scopus 로고
    • The natural history of neoplastic development
    • Marcel Dekker, Inc., New York
    • 6 Pilot, H. C. (1986) The natural history of neoplastic development. In Fundamentals of Oncology, pp. 163-200, Marcel Dekker, Inc., New York
    • (1986) Fundamentals of Oncology , pp. 163-200
    • Pilot, H.C.1
  • 8
    • 0013680667 scopus 로고
    • Phenotypic and genetic markers of cancer: Turning point in research
    • (Aaronson, S. A., Frati, L. and Verna, R., eds.), Plenum Press, New York
    • 8 Frati, L., Cortesi, E., Ficorella, C., Manzari, V. and Verna, R. (1984) Phenotypic and genetic markers of cancer: turning point in research. In Genetic and Phenotypic Markers of Tumors (Aaronson, S. A., Frati, L. and Verna, R., eds.), pp. 1-20, Plenum Press, New York
    • (1984) Genetic and Phenotypic Markers of Tumors , pp. 1-20
    • Frati, L.1    Cortesi, E.2    Ficorella, C.3    Manzari, V.4    Verna, R.5
  • 9
    • 0022337677 scopus 로고
    • Isolation of tumor-secreted products from human carcinoma cells maintained in a defined protein-free medium
    • 9 Alderman, E. M., Lobb, R. R. and Fett, J. W (1985) Isolation of tumor-secreted products from human carcinoma cells maintained in a defined protein-free medium. Proc. Natl. Acad. Sci U.S.A. 82, 5771-5775
    • (1985) Proc. Natl. Acad. Sci U.S.A. , vol.82 , pp. 5771-5775
    • Alderman, E.M.1    Lobb, R.R.2    Fett, J.W.3
  • 10
    • 0030830309 scopus 로고    scopus 로고
    • The cellular basis of tumor progression
    • 10 Heppner, G. and Miller, F. R. (1998) The cellular basis of tumor progression. Int. Rev. Cytol. 177, 1-56
    • (1998) Int. Rev. Cytol. , vol.177 , pp. 1-56
    • Heppner, G.1    Miller, F.R.2
  • 11
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • 11 Nowell, P. C. (1976) The clonal evolution of tumor cell populations. Science 194, 23-28
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 12
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes: Gatekeepers and caretakers
    • 12 Kinzler, K. W. and Vogelstein, B. (1997) Cancer-susceptibility genes: gatekeepers and caretakers. Nature (London) 386, 761,763
    • (1997) Nature (London) , vol.386 , pp. 761
    • Kinzler, K.W.1    Vogelstein, B.2
  • 13
    • 0033011006 scopus 로고    scopus 로고
    • Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog
    • 13 Tomlinson, I. and W., Bodmer (1999) Selection, the mutation rate and cancer: ensuring that the tail does not wag the dog. Nat Med 5, 11-12
    • (1999) Nat Med , vol.5 , pp. 11-12
    • Tomlinson, I.1    Bodmer, W.2
  • 14
    • 0002748276 scopus 로고
    • Detection of transforming genes from radiation transformed human epidermal keratinocytes by a tumorigenicity assay
    • (Rhim, J. S. and Dritschilo, A., eds.), The Humana Press Inc., Totowa, NJ
    • 14 Thraves, P., Reynolds, S., Salehi, Z., Kim, W. K., Yang, J. H., Rhim, J. S. and Dritschilo, A. (1991) Detection of transforming genes from radiation transformed human epidermal keratinocytes by a tumorigenicity assay in Neoplastic Transformation in Human Cell Culture (Rhim, J. S. and Dritschilo, A., eds.), pp. 93-101, The Humana Press Inc., Totowa, NJ
    • (1991) Neoplastic Transformation in Human Cell Culture , pp. 93-101
    • Thraves, P.1    Reynolds, S.2    Salehi, Z.3    Kim, W.K.4    Yang, J.H.5    Rhim, J.S.6    Dritschilo, A.7
  • 15
    • 0024367253 scopus 로고
    • A view of the relation between carcinogenesis and mutagenesis
    • 15 Lijinsky, W. (1989) A view of the relation between carcinogenesis and mutagenesis. Environ. Mol. Mutagen. 14, 78-84
    • (1989) Environ. Mol. Mutagen. , vol.14 , pp. 78-84
    • Lijinsky, W.1
  • 16
    • 0029640789 scopus 로고
    • Oncogenes and cancer
    • 16 Duesberg, P. H. (1995) Oncogenes and cancer. Science 267, 1407-1408
    • (1995) Science , vol.267 , pp. 1407-1408
    • Duesberg, P.H.1
  • 17
    • 0025602166 scopus 로고
    • Human tumor suppressor genes
    • 17 Stanbridge, E. J. (1990) Human tumor suppressor genes. Annu. Rev. Genet 24, 615-657
    • (1990) Annu. Rev. Genet , vol.24 , pp. 615-657
    • Stanbridge, E.J.1
  • 18
    • 0034724312 scopus 로고    scopus 로고
    • Aneuploidy versus gene mutation hypothesis: Recent study claims mutation, but is found to support aneuploidy
    • 18 Li, R., Sonik, A., Stindl, R., Rasnick, D. and Duesberg, P. (2000) Aneuploidy versus gene mutation hypothesis: recent study claims mutation, but is found to support aneuploidy. Proc. Natl. Acad. Sci. U.S.A. 97, 3236-3241
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 3236-3241
    • Li, R.1    Sonik, A.2    Stindl, R.3    Rasnick, D.4    Duesberg, P.5
  • 19
    • 0000800143 scopus 로고
    • Role of chromosomes in cancerogenesis, as studied in serial tissue culture of mammalian cells
    • 19 Levan, A. and Biesele, J. J. (1958) Role of chromosomes in cancerogenesis, as studied in serial tissue culture of mammalian cells. Ann. N. Y. Acad. Sci. 71, 1022-1053
    • (1958) Ann. N. Y. Acad. Sci. , vol.71 , pp. 1022-1053
    • Levan, A.1    Biesele, J.J.2
  • 21
    • 0025306434 scopus 로고
    • Are human cancers ever diploid - or often trisomie? Conflicting evidence from direct preparations and culture
    • 21 Atkin, N B. and Baker, M. C. (1990) Are human cancers ever diploid - or often trisomie? Conflicting evidence from direct preparations and culture. Cytogenet. Cell Genet. 53, 58-60
    • (1990) Cytogenet. Cell Genet. , vol.53 , pp. 58-60
    • Atkin, N.B.1    Baker, M.C.2
  • 22
    • 0015618879 scopus 로고
    • Genetic effects of aneuploidy
    • 22 Sandler, L. and Hecht, F. (1973) Genetic effects of aneuploidy. Am. J. Hum. Genet. 25, 332-339
    • (1973) Am. J. Hum. Genet. , vol.25 , pp. 332-339
    • Sandler, L.1    Hecht, F.2
  • 24
    • 0002298217 scopus 로고
    • Predisposing to chromosome instability and cancer
    • (German, J., ed.), John Wiley & Sons, New York
    • 24 German, J. (1974) Predisposing to chromosome instability and cancer. In Chromosomes and Cancer. vol. 1 (German, J., ed.), pp. 601-617, John Wiley & Sons, New York
    • (1974) Chromosomes and Cancer. , vol.1 , pp. 601-617
    • German, J.1
  • 25
    • 0020987278 scopus 로고
    • Karyotypic progression in human tumors
    • 25 Wolman, S. R. (1983) Karyotypic progression in human tumors. Cancer Metastasis Rev. 2, 257-293
    • (1983) Cancer Metastasis Rev. , vol.2 , pp. 257-293
    • Wolman, S.R.1
  • 26
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • 26 Hayflick, L. and Moorhead, P. S. (1961) The serial cultivation of human diploid cell strains. Exp. Cell Res. 25, 585-621
    • (1961) Exp. Cell Res. , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 27
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • 27 Hayflick, L. (1965) The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37, 614-636
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 28
    • 84965808555 scopus 로고
    • Visible light and skin tumors induced with benzpyrene in mice
    • 28 Morton, J. J., Luce-Clausen, E. M. and Mahoney, E. B. (1942) Visible light and skin tumors induced with benzpyrene in mice. Cancer Res. 2, 256-260
    • (1942) Cancer Res. , vol.2 , pp. 256-260
    • Morton, J.J.1    Luce-Clausen, E.M.2    Mahoney, E.B.3
  • 29
    • 84965831784 scopus 로고
    • The kinetics of papilloma formation in benzpyrene-treated mice
    • 29 Charles, D. R. and Luce-Clausen, E. M. (1942) The kinetics of papilloma formation in benzpyrene-treated mice. Cancer Res. 2, 261-263
    • (1942) Cancer Res. , vol.2 , pp. 261-263
    • Charles, D.R.1    Luce-Clausen, E.M.2
  • 30
    • 84965187257 scopus 로고
    • The age distribution of cancer and the multi-stage theory of carcinogenesis
    • 30 Armitage, P. and Doll, R. (1954) The age distribution of cancer and the multi-stage theory of carcinogenesis. Br. J. Cancer 8. 1-12
    • (1954) Br. J. Cancer , vol.8 , pp. 1-12
    • Armitage, P.1    Doll, R.2
  • 31
    • 84883833036 scopus 로고
    • Aneuploidy in the degenerative phase of serial cultivation of human cell strains
    • 31 Saksela, E. and Moorhead, P. S. (1963) Aneuploidy in the degenerative phase of serial cultivation of human cell strains. Proc. Natl. Acad. Sci. U.S.A. 50, 390-395
    • (1963) Proc. Natl. Acad. Sci. U.S.A. , vol.50 , pp. 390-395
    • Saksela, E.1    Moorhead, P.S.2
  • 33
    • 0020661091 scopus 로고
    • Downs syndrome-a disruption of homeostasis
    • 33 Shapiro, B. L. (1983) Downs syndrome-a disruption of homeostasis. Am. J. Med. Genet. 14, 241-269
    • (1983) Am. J. Med. Genet. , vol.14 , pp. 241-269
    • Shapiro, B.L.1
  • 34
    • 0015451321 scopus 로고
    • Replication rate and lifespan of cultured fibroblasts in Down's syndrome
    • 34 Schneider, E. L. and Epstein, C. J. (1972) Replication rate and lifespan of cultured fibroblasts in Down's syndrome. Proc. Soc. Exp. Biol. Med. 141, 1092-1094
    • (1972) Proc. Soc. Exp. Biol. Med. , vol.141 , pp. 1092-1094
    • Schneider, E.L.1    Epstein, C.J.2
  • 35
    • 0032526483 scopus 로고    scopus 로고
    • Aneuploidy analysis in fibroblasts of human premature aging syndromes by FISH during in vitro cellular aging
    • 35 Mukherjee, A. B. and Costello, C. (1998) Aneuploidy analysis in fibroblasts of human premature aging syndromes by FISH during in vitro cellular aging. Mech. Ageing Dev. 103, 209-222
    • (1998) Mech. Ageing Dev. , vol.103 , pp. 209-222
    • Mukherjee, A.B.1    Costello, C.2
  • 36
    • 84883840386 scopus 로고
    • Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
    • 36 Todaro, G. T. and Green, H. (1963) Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J.Cell Biol. 7, 299-313
    • (1963) J.cell Biol. , vol.7 , pp. 299-313
    • Todaro, G.T.1    Green, H.2
  • 37
    • 0029760993 scopus 로고    scopus 로고
    • Chaotic oscillations in cultured cells: Rat prostate cancer
    • 37 Posadas, E. M., Criley, S. R. and Coffey, D. S. (1996) Chaotic oscillations in cultured cells: rat prostate cancer. Cancer Res. 56, 3682-3688
    • (1996) Cancer Res. , vol.56 , pp. 3682-3688
    • Posadas, E.M.1    Criley, S.R.2    Coffey, D.S.3
  • 38
    • 0003568098 scopus 로고    scopus 로고
    • One-dimensional maps
    • (Thomas, F., Banchoff, K. D., Gonnet, G., Marsden, J. and Wagon, S., eds.), Springer, New York
    • 38 Alligood, K. T., Sauer, T. D. and Yorke, J. A. (1996) One-dimensional maps. In Chaos: An Introduction to Dynamical Systems, (Thomas, F., Banchoff, K. D., Gonnet, G., Marsden, J. and Wagon, S., eds.), pp. 1-42, Springer, New York
    • (1996) Chaos: An Introduction to Dynamical Systems , pp. 1-42
    • Alligood, K.T.1    Sauer, T.D.2    Yorke, J.A.3
  • 39
    • 0013654406 scopus 로고    scopus 로고
    • The parameter as king
    • Joseph Henry Press, Washington DC
    • 39 Williams, G. P. (1997) The parameter as king In Chaos Theory Tamed, pp. 161-167, Joseph Henry Press, Washington DC
    • (1997) Chaos Theory Tamed , pp. 161-167
    • Williams, G.P.1
  • 40
    • 0024564790 scopus 로고
    • Chromosome error propagation and cancer
    • 40 Holliday, R. (1989) Chromosome error propagation and cancer. Trends Genet. 5, 42-45
    • (1989) Trends Genet. , vol.5 , pp. 42-45
    • Holliday, R.1
  • 41
  • 42
    • 0025375922 scopus 로고
    • Mathematical models of gene amplification with applications to cellular drug resistance and tumorigenicity
    • 42 Kimmel, M. and Axelrod, D. E. (1990) Mathematical models of gene amplification with applications to cellular drug resistance and tumorigenicity. Genetics 125, 633-644
    • (1990) Genetics , vol.125 , pp. 633-644
    • Kimmel, M.1    Axelrod, D.E.2
  • 46
    • 0023789113 scopus 로고
    • Detection of chromosome aneuploidy in interphase nuclei from human primary breast tumors using chromosome-specific repetitive DNA probes
    • 46 Devilee, P., Thierry, R. F., Kievits, T., Kolluri, R., Hopman, A. H. N., Willard, H. F., Pearson, P. L. and Cornelisse, C. J. (1988) Detection of chromosome aneuploidy in interphase nuclei from human primary breast tumors using chromosome-specific repetitive DNA probes. Cancer Res. 48, 5825-5830
    • (1988) Cancer Res. , vol.48 , pp. 5825-5830
    • Devilee, P.1    Thierry, R.F.2    Kievits, T.3    Kolluri, R.4    Hopman, A.H.N.5    Willard, H.F.6    Pearson, P.L.7    Cornelisse, C.J.8
  • 47
    • 0031917334 scopus 로고    scopus 로고
    • Numerical aberrations of chromosomes 16, 17, and 18 in hepatocullular carcinoma
    • 47 Kato, A., Kubo, K., Kurokawa, F., Okita, K., Oga, A. and Murakami, T. (1998) Numerical aberrations of chromosomes 16, 17, and 18 in hepatocullular carcinoma. Dig. Dis. Sci. 43, 1-7
    • (1998) Dig. Dis. Sci. , vol.43 , pp. 1-7
    • Kato, A.1    Kubo, K.2    Kurokawa, F.3    Okita, K.4    Oga, A.5    Murakami, T.6
  • 48
    • 84908007911 scopus 로고
    • A new theory on the cancer-inducing mechanism
    • 48 Nordling, C. O. (1953) A new theory on the cancer-inducing mechanism. Br. J. Cancer 7, 68-72
    • (1953) Br. J. Cancer , vol.7 , pp. 68-72
    • Nordling, C.O.1
  • 49
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • 49 Kinzler, K. and Vogelstein, B. (1996) Lessons from hereditary colorectal cancer. Cell 87, 159-170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.1    Vogelstein, B.2
  • 50
    • 0026714335 scopus 로고
    • Latent viruses and mutated oncogenes: No evidence for pathogenicity
    • 50 Duesberg, P. H. and Schwartz, J. R. (1992) Latent viruses and mutated oncogenes: no evidence for pathogenicity. Prog. Nucleic Acid Res. Mol. Biol. 43, 135-204
    • (1992) Prog. Nucleic Acid Res. Mol. Biol. , vol.43 , pp. 135-204
    • Duesberg, P.H.1    Schwartz, J.R.2
  • 51
    • 0013674273 scopus 로고
    • The epidemiology of cancer
    • W. H. Freeman and Company, San Francisco
    • 51 Cairns, J. (1978) The epidemiology of cancer. In Cancer: Science and Society, pp. 35-61, W. H. Freeman and Company, San Francisco
    • (1978) Cancer: Science and Society , pp. 35-61
    • Cairns, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.