Role of Ser-65 in the activity of α-galactosidase A: Characterization of a point mutation (S65T) detected in a patient with Fabry disease

Archives of Biochemistry and Biophysics

Volumn 377, Issue 2, 2000, Pages 228-233

  Ishii, Satoshi ^a   Suzuki, Yoshiyuki ^b   Fan, Jian Qiang ^c  

^a Usuki Bio Research Center   (Japan)

^b INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Chemical chaperone; Fabry disease; Mutagenesis; Thermostability; Galactosidase A

Indexed keywords

ALPHA GALACTOSIDASE; ENZYME INHIBITOR; GENE PRODUCT; PLASMID DNA;

AMINO ACID SUBSTITUTION; ARTICLE; BACULOVIRUS; CELL STRAIN COS1; ENZYME DEFECT; ENZYME DEFICIENCY; ENZYME SUBSTRATE; FABRY DISEASE; GENE EXPRESSION SYSTEM; GENETIC DISORDER; GENETIC TRANSFECTION; HUMAN; INSECT; MICHAELIS CONSTANT; PH; POINT MUTATION; PRIORITY JOURNAL; THERMOSTABILITY;

EID: 0034657297     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.2000.1743     Document Type: Article

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