Human α-galactosidase A: Characterization of the N-linked oligosaccharides on the intracellular and secreted glycoforms overexpressed by Chinese hamster ovary cells

Glycobiology

Volumn 8, Issue 4, 1998, Pages 329-339

  Matsuura, Fumito ^a   Ohta, Masaya ^a   Ioannou, Yiannis A ^b   Desnick, Robert J ^b  

^a FUKUYAMA UNIVERSITY   (Japan)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Chinese hamster ovary cell; Constitutive secretory pathway; Mannose 6 phosphate; N linked oligosaccharide chain; Recombinant human galactosidase A

Indexed keywords

ALPHA GALACTOSIDASE; ASPARAGINE LINKED OLIGOSACCHARIDE; N ACETYLNEURAMINIC ACID DERIVATIVE; SIALIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; CARBOHYDRATE ANALYSIS; CHO CELL; CONTROLLED STUDY; ENZYME CHEMISTRY; ENZYME RELEASE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION;

ALPHA-GALACTOSIDASE; ANIMALS; CARBOHYDRATE SEQUENCE; CHO CELLS; CRICETINAE; GENE EXPRESSION; GLYCOCONJUGATES; GLYCOSYLATION; HUMANS; LYSOSOMES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OLIGOSACCHARIDES; RECOMBINANT PROTEINS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0031901350     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/8.4.329     Document Type: Article

References (40)

1. Amano, J. and Kobata, A. (1986) Purification and characterization of a novel α-mannosidase from Aspergillus saitoi. J. Biochem. (Tokyo), 99, 1645-1654.
2. Barton, N.W., Furbish, F.S., Murray, G.J., Garfield, M. and Brady, R.O. (1990) Therapeutic response to intravenous infusions of glucocerebrosidase in a patient with Gaucher disease. Proc. Natl. Acad. Sci. USA, 87, 1913-1916.
3. 2tu-PA expressed in Chinese hamster ovary cells. Eur. J. Biochem., 212, 639-656.
4. Bishop, D.F. and Desnick, R.J. (1981) Affinity purification of α-galactosidase A from human spleen, placenta, and plasma with elimination of pyrogen contamination: properties of the purified splenic enzyme compared to other forms. J. Biol. Chem., 256, 1307-1316.
5. Bishop, D.F. and Sweeley, C.C. (1978) Plasma α-galactosidase A: Properties and comparisons with tissue α-galactosidases. Biochim. Biophys. Acta, 525, 399-409.
6. Bishop, D.F., Calhoun, D.H., Bernstein, H.S., Hantzopoulos, P., Quinn, M. and Desnick, R.J. (1986) Human α-galactosidase A: nucleotide sequence of a cDNA clone encoding the mature enzyme. Proc. Natl. Acad. Sci. USA, 83, 4859-4863.
7. Bishop, D.F., Kornreich, R. and Desnick, R.J. (1988) Structural organization of the human α-galactosidase A gene: further evidence for the absence of a 3′ untranslated region. Proc. Natl. Acad. Sci. USA, 85, 3903-3907.
8. Desnick, R.J., Dean, K.J., Grabowski, G., Bishop, D.F. and Sweeley, C.C. (1979) Enzyme therapy in Fabry disease: differential in vivo plasma clearance and metabolic effectiveness of plasma and splenic α-galactosidase A isozymes. Proc. Natl. Acad. Sci. USA, 76, 5326-5330.
9. Desnick, R.J., Ioannou, Y.A. and Eng, C.M. (1995) α-Galactosidase A deficiency: Fabry disease. In Scriver, C.R., Beaudet, A.L., Sly, W.S. and Valle, D. (eds.), The Metabolic and Molecular Basis of Inherited Disease, 7th ed. McGraw-Hill, New York, pp. 2741-2784.
10. Furbish, F.S., Steer, C.J., Krett, N.L. and Barranger, J.A. (1981) Uptake and distribution of placental glucocerebrosidase in rat hepatic cells and effects of sequential deglycosylation. Biochim. Biophys. Acta, 673, 425-434.
11. 1 cells. J. Biol. Chem., 256, 13060-13067.
12. Hantzopoulos, P.A. and Calhoun, D.H. (1987) Expression of the human α-galactosidase A in Escherichia coli K-12. Gene, 57, 159-169.
13. Hara, S., Takemori, Y., Yamaguchi, M., Nakamura, M. and Ohkura, Y. (1987) Fluorometric high-performance liquid chromatography of N-acetyl- and N-glycolylneuramic acids and its application to their microdetermination in human and animal sera, glycoproteins, and glycolipids. Anal. Biochem., 164, 138-145.
14. Ioannou, Y.A., Bishop, D.F. and Desnick, R.J. (1992) Overexpression of human α-galactosidase A results in its intracellular aggregation, crystallization in lysosomes, and selective secretion. J. Cell Biol., 119, 1137-1150.
15. Kornreich, R., Desnick, R.J. and Bishop, D.F. (1989) Nucleotide sequence of the human α-galactosidase A gene. Nucleic Acids Res., 17, 3301-3302.
16. Kozutsumi, Y., Kawasaki, T. and Yamashina, I. (1986) Structures of galactose-containing oligosaccharides of α-mannosidase from porcine kidney. J. Biochem. (Tokyo), 100, 505-512.
17. Krag, S.S. and Robbins, A.R. (1982) A Chinese hamster ovary cell mutant deficient in glucosylation of lipid-linked oligosaccharide synthesizes lysosomal enzymes of altered structure and function. J. Biol. Chem., 257, 8424-8431.
18. Kress, B.C., Hirani, S., Freeze, H.H., Little, L. and Miller, A.L. (1982) Mucolipidosis III β-N-acetyl-D-hexosaminidase A: purification and properties. Biochem. J., 207, 421-428.
19. Kusiak, J.W., Quirk, J.M. and Brady, R.O. (1978) Purification and properties of the two major isozymes of α-galactosidase from human placenta. J. Biol. Chem., 253, 184-190.
20. LeDonne, N.C., Jr., Fairley, J.L. and Sweeley, C.C. (1983) Biosynthesis of α-galactosidase A in cultured chang liver cells. Arch. Biochem. Biophys., 224, 186-195.
21. Lemansky, P., Bishop, D.F., Desnick, R.J., Hasilik, A. and von Figura, K. (1987) Synthesis and processing of α-galactosidase A in human fibroblasts: evidence for different mutations in Fabry disease. J. Biol. Chem., 262, 2062-2065.
22. Li, Y.-T. and Li, S.-C. (1972) α-Mannosidase, β-N-acetylhexosaminidase, and β-galactosidase from jack bean meal. Methods Enzymol., 28, 702-713.
23. Matsuura, F. and Imaoka, A. (1988) Chromatographic separation of asparagine-linked oligosaccharides labeled with an ultravioletabsorbing compound, p-aminobenzoic acid ethyl ester. Glycoconjugate J., 5, 13-26.
24. Matsuura, F., Ohta, M., Murakami, K., Hirano, K. and Sweeley, C.C. (1992) The combination of normal phase with reversed phase high performance liquid chromatography for the analysis of asparagine-linked neutral oligosaccharides labelled with p-aminobenzoic ethyl ester. Biomed. Chromatogr., 6, 77-83.
25. Matsuura, F., Ohta, M., Murakami, K. and Matsuki, Y. (1993) Structures of asparagine linked oligosaccharides of immunoglobulins (IgY) isolated from egg-yolk of Japanese quail. Glycoconjugate J., 10, 202-213.
26. Miller, A.L., Kress, B.C., Stein, R., Kinnon, C., Kern, H., Schneider, J.A. and Harms, E. (1981) Properties of N-acetyl-β-D-hexosaminidase from isolated normal and I-cell lysosomes. J. Biol. Chem., 256, 9352-9362.
27. Mizuochi, T., Nishimura, Y., Kato, K. and Kobata, A. (1981) Comparative studies of asparagine-linked oligosaccharide structures of rat liver microsomal and lysosomal β-glucuronidases. Arch. Biochem. Biophys., 209, 298-303.
28. Murali, R., Ioannou, Y.A., Desnick, R.J. and Burnett, R.M. (1994) Crystallization and preliminary X-ray analysis of human α-galactosidase A complex. J. Mol. Biol., 239, 578-580.
29. Mutsaers, J.H.G.M., van Halbeek, H., Vliegenthart, J.F.G., Tager, J.M., Reuser, A.J.J., Kroos, M. and Galjaard, H. (1987) Determination of the structure of the carbohydrate chains of acid α-glucosidase from human placenta. Biochim. Biophys. Acta, 911, 244-251.
30. Nakao, Y., Kozutsumi, Y., Kawasaki, T., Yamashina, I., van Halbeek, H. and Vliegenthar, J.F.G. (1984) Oligosaccharides on cathepsin D from porcine spleen. Arch. Biochem. Biophys., 229, 43-54.
31. Natowicz, M., Baenziger, J.U. and Sly W.S. (1982) Structural studies of the phosphorylated high mannose-type oligosaccharides on human β-glucuronidase. J. Biol. Chem., 257, 4412-4420.
32. Ohta, M., Hamako, J., Yamamoto, S., Hatta, H., Kim, M., Yamamoto, T., Oka, S., Mizuochi, T. and Matsuura, F. (1991) Structures of asparagine-linked oligosaccharides from hen egg-yolk antibody (IgY). Occurrence of unusual glucosylated oligo-mannose type oligosaccharides in a mature glycoprotein. Clycoconjugate J., 8, 400-413.
33. Ohta, M., Emi, S., Iwamoto, H., Hirose, J., Hiromi, K., Itoh, H., Shin, T., Murao, S. and Matsuura, F. (1996) Novel β-D-galactofuranose-containing high-mannose type oligosaccharides in ascorbate oxidase from Acremonium sp. HI-25. Biosci. Biotech. Biochem., 60, 1123-1130.
34. Sasaki, H., Bothner, B., Dell, A. and Fukuda, M. (1987) Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA. J. Biol. Chem., 262, 12059-12076.
35. Tai, T., Yamashita, K., Ogata-Arakawa, M. Koide, N., Muramatsu, T., Iwashita, S., Inoue, Y. and Kobata, A. (1975) Structural studies of two ovalbumin glycopeptides in relation to the endo-β-N-acetylglucosaminidase specificity. J. Biol. Chem., 250, 8569-8575.
36. Takeuchi, M., Takasaki, S., Miyazaki, H., Kato, T., Hoshi, S., Kochibe, N. and Kobata, A. (1988) Comparative study of the asparagine-linked sugar chains of human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells. J. Biol. Chem., 263, 3657-3663.
37. Taniguchi, T., Mizuochi, T., Towatari, T., Katunuma, N. and Kobata, A. (1985) Structural studies on the carbohydrate moieties of rat liver cathepsins B and H. J. Biochem. (Tokyo), 97, 973-976.
38. Varki, A. and Kornfeld, S. (1983) The spectrum of anionic oligosaccharides released by endo-β-N-acetylglucosaminidase H from glycoproteins: structural studies and interactions with the phosphomannosyl receptor. J. Biol. Chem., 258, 2808-2818.
39. Vetrie, D., Bobrow, M. and Harris, A. (1993) Construction of a 5.2-megabase physical map of the human X chromosome at Xq22 using pulsed-field gel electrophoresis and yeast artificial chromosomes. Genomics, 15, 631-642.
40. Wang, W.T., LeDonne, N.C., Jr., Ackerman, B. and Sweeley, C.C. (1984) Structural characterization of oligosaccharides by high-performance liquid chromatography, fast-atom bombardment-mass spectrometry, and exoglycosidase digestion. Anal. Biochem., 141, 366-381.