Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-2'-deoxyadenosine

Biochemical Pharmacology

Volumn 59, Issue 10, 2000, Pages 1237-1243

  Bontemps, Françoise ^a   Delacauw, Anne ^a   Cardoen, Sabine ^a   Van Den Neste, Eric ^a,b   Van Den Berghe, Georges ^a  

^a DE DUVE INSTITUTE   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

2 chloro 2' deoxyadenosine; 2 chloroadenine; 2 chloroadenosine; Apopain caspase 3; CLL lymphocytes; EHEB cells

Indexed keywords

ADENINE DERIVATIVE; CASPASE 3; CLADRIBINE; DNA FRAGMENT; DRUG METABOLITE; NUCLEOTIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CYTOTOXICITY; DRUG METABOLISM; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL;

ADENINE; ANTINEOPLASTIC AGENTS; CLADRIBINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; NUCLEOTIDES; TRITIUM; TUMOR CELLS, CULTURED;

EID: 0034657005     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00258-6     Document Type: Article

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