Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: A double-blind, randomized placebo- controlled study

Cancer

Volumn 88, Issue 8, 2000, Pages 1916-1928

  Ogilvie, Gregory K ^a   Fettman, Martin J ^a   Mallinckrodt, Craig H ^a   Walton, Judy A ^a   Hansen, Rodney A ^a   Davenport, Deborah J ^b   Gross, Kathy L ^b   Richardson, K L ^a   Rogers, Quinton ^c   Hand, Michael S ^b  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b Hill's Pet Nutrition Inc   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Docosahexaenoic Acid; Dogs; Eicosapentaenoic acid; Fish oil; Lymphoma

Indexed keywords

ARGININE; DOXORUBICIN; FISH OIL; OMEGA 3 FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CANCER REGRESSION; CANCER SURVIVAL; CONTROLLED STUDY; DIETARY INTAKE; DOSE RESPONSE; DRUG EFFECT; DRUG TOLERANCE; LYMPHOMA; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME;

ANIMALS; ANTINEOPLASTIC AGENTS; ARGININE; CACHEXIA; DIET; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; DISEASE-FREE SURVIVAL; DOCOSAHEXAENOIC ACIDS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DOXORUBICIN; EICOSAPENTAENOIC ACID; FATTY ACIDS; FISH OILS; LACTIC ACID; LYMPHOMA, LYMPHOBLASTIC; SURVIVAL ANALYSIS;

EID: 0034655143     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(20000415)88:8<1916::AID-CNCR22>3.0.CO;2-F     Document Type: Article

References (53)

1. Vail DM, Ogilvie GK, Wheeler SL. Metabolic alterations in patients with cancer cachexia. Comp Cont Ed Pract Vet 1990;12:381-7.
2. Brennan MF. Uncomplicated starvation versus cancer cachexia. Cancer Res 1977;37:2359-64.
3. Chlebowski RT, Heber D. Metabolic abnormalities in cancer patients: carbohydrate metabolism. Surg Clin N Am 1986; 66:957-68.
4. Heber D, Byerly LO, Chlebowski RT. Metabolic abnormalities in the cancer patient. Cancer 1985;55:225-9.
5. Dewys WD. Pathophysiology of cancer cachexia: current understanding and areas of future research. Cancer Res 1982;2(Suppl 5):721-6.
6. Kern KA, Norton JA. Cancer cachexia. J Parenteral Enterai Nutr 1988;12:286-98.
7. Ogilvie GK, Vail DM, Wheeler SL, Fettman MJ, Salman MD, Cooper MF, et al. Effect of chemotherapy and remission on carbohydrate metabolism in dogs with lymphoma. Cancer 1992;69:233-8.
8. Ogilvie GK, Ford RD, Vail DM, Walters LM, Babineau C, Fettman MJ. Alterations in lipoprotein profiles in dogs with lymphoma. J Vet Intern Med 1994;8:62-6.
9. Vail DM, Ogilvie GK, Wheeler SL, Fettman MJ, Johnston SD, Hegstad RL, et al. Alterations in carbohydrate metabolism in canine lymphoma. J Vet Intern Med 1990;4:8-14.
10. Ogilvie GK, Walters L, Salman MD, Fettman MJ, Johnston SD, Hegstad RL. Alterations in carbohydrate metabolism in dogs with nonhematopoietic malignancies. Am J Vet Res 1997;58:277-81.
11. Ogilvie GK, Walters LM, Greeley SG. Concentration of alpha 1-glycoprotein in dogs with malignant neoplasia. J Am Vet Med Assoc 1993;203:1144-6.
12. Karmall RA. Historical perspective and potential use of n-3 fatty acids in therapy of cancer cachexia. Nutrition 1996;12: S2-4.
13. Kinoshita K, Noguchi M, Tanaka M. Effects of linoleic acid, eicosapentaenoic acid and docosahexaenoic acid on the growth and metastases of MM48 mammary tumor transplants in mice. Int J Oncol 1996;8:575-81.
14. Chicco A, D'Alessandro ME, Karahatas L, Gutman R, Lombardo YB. Effect of moderate levels of dietary fish oil on insulin secretion and sensitivity, and pancreatic insulin content in normal rats. Ann Nutr Metab 1996;40:61-70.
15. Pomposelli JJ, Flores EA, Blackburn GL, Zeisel SH, Bistrian BR. Diets enriched with n-3 fatty acids ameliorate lactic acidosis by improving endotoxin-induced tissue hypoperfusion in guinea pigs. Ann Surg 1991;213:166-77.
16. Kaiser L, Boyd NF, Kriukow V, Trichler D. Fish consumption and breast cancer risk: an ecological study. Nutr Cancer 1989;12:61-8.
17. Yamamoto D, Kiyozuka Y, Adachi Y, Takada H, Hioki K, Tsubura A. Synergistic action of apoptosis induced by eicosapentaenoic acid and TNP-470 on human breast cancer cells. Breast Cancer Res Treat 1999;55:149-60.
18. Norton JA, Gorschboth CM, Wesley RA, Burt ME, Brennan MF. Fasting plasma amino acid levels in cancer patients. Cancer 1985;56:1181-6.
19. Kirk SJ, Hurson M, Regan MC, Holt DR, Wasserkrug HL, Barbul A. Arginine stimulates wound healing and immune function in elderly human beings. Surgery 1983;114:155-60.
20. Lowell JA, Parries HL, Blackburn GL. Dietary immunomodulation: beneficial effect on oncogenesis and tumor growth. Crit Care Med 1990;18:5145-65.
21. Daly JM, Reynolds J, Thorn A, Kinsley L, Dietrick-Gallagher M, Shou J, et al. Immune and metabolic effects of arginine in the surgical patient. Ann Surg 1988;208:512-23.
22. Owen LN. TNM classification of tumors of domestic animals. Geneva: World Health Organization, 1981.
23. Valerius KD, Ogilvie GK, Mallinckrodt CH, Goetze DM. Doxorubicin alone or in combination with asparaginase, followed by cyclophosphamide, vincristine, and prednisone for treatment of multicentric lymphoma in dogs: 121 cases (1987-1995). JAm Vet Med Assoc 1997;210:512-6.
24. Ogilvie GK, Walters LM, Fettman MJ, Hand MS, Salman MD, Wheeler SL. Energy expenditure in dogs with lymphoma fed two specialized diets. Cancer 1993;71:3146-52.
25. Fedak MA, Pinshow B, Schmidt-Nielsen K. Energy cost of bipedal running. Am J Physiol 1974;277:1038-44.
26. Fox LE, King RR, Shi F, Kurzman ID, Macewen EG, Kubilis PS. Induction of serum tumor necrosis factor-alpha and interleukin-6 activity by liposome encapsulated muramyl tripeptide-phosphatidylethanolamine (L-MTP-PE). Cancer Biother 1994;9:329-40.
27. Elmslie RE, Ogilvie GK, Dow SW, Gasper P, Hoover EA, Cooper MF, et al. Evaluation of a biologic response modifier derived from Serratia marcescens: effects on feline macrophages and usefulness for the prevention and treatment of viremia in feline leukemia virus-infected cats. Mol Biother 1991;3:231-8.
28. Goitsuka R, Ohashi T, Ono K, Yasukawa K, Koishibara Y, Fukui H, et al. IL-6 activity in feline infectious peritonitis. J Immunol 1990;144:2599-603.
29. van Snick J, Cayphass S, Vink A, Uyttenhove C, Courie PG, Rubira MR, et al. Purification of NH2-terminal amino acid sequence of a T-cell derived cytokine with growth factor activity for B-cell hybridomas. Proc Natl Acad Sci USA 1986; 83:9679-83.
30. Hansen MB, Nielson SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 1989;119: 203-6.
31. Zicker SC, Rogers QR. Temporal changes in the concentrations of amino acids in plasma and whole blood of healthy neonatal foals from birth to two days of age. Am J Vet Res 1994;55:1020-9.
32. Zicker SC, Rogers QR. Use of plasma amino acid concentrations in the diagnosis of nutritional and metabolic diseases in veterinary medicine. In: Kaneko JJ, editor. Proceedings IVth Congress of the International Society for Animal Clinical Biochemistry University of California, Davis, CA, July 18-21, 1990.
33. IP C, Birt DF, Rogers AE, Mettlin C, editors. Dietary fat and cancer. Prog Clin Biol Res 1986;222:3-885.
34. Ohta A, Mayo MC, Kramer N, Lands WE. Rapid analysis of fatty acids in plasma lipids. Lipids 1990;25:742-7.
35. Littel RC, Milliken GA, Stroup, WW, Wolfinger RD. The SAS system for mixed models. Cary, NC: SAS Institute Inc., 1996: 87-134.
36. SAS. SAS/Stat users guide. Version 6.03. 4th ed. Cary, NC: SAS Institute Inc., 1989:1024-76.
37. Sokal RR, Rohlf FJ. Biometry. 3rd ed. New York: W.H. Freeman and Co., 1995:598-609.
38. Cox DR, Oates D. The analysis of survival data. New York: Chapman and Hall, 1984:1-23.
39. Begin ME, Ells G, Horrobin DF. Polyunsaturated fatty acids-induced cytotoxicity against tumor cells and its relationship to lipid peroxidation. J Natl Cancer Inst 1988;80:188-94.
40. Lefer AM. Significance of lipid mediators in shock states. Circ Shock 1989;27:3-12.
41. Abou-el-Ela SH, Prasse KW, Carroll R, Wade AE, Dhar-wadkar S, Bunch OR. Eicosanoid synthesis in 7, 12-demthylbenz(a)-anthracene-induced mammary carcinomas in Sprague-Dawley rats fed primrose oil, menhaden oil, or corn oil diets. Lipids 1988;23:948-54.
42. Noguchi M, Rose DP, Earashi M, Miyazaki I. The role of fatty acids and eicosanoid synthesis inhibitors in breast carcinoma. Oncology 1995;52:265-71.
43. Plumb JA, Luo W, Kerr DJ. Effect of polyunsaturated fatty acids on the drug sensitivity of human tumor cell lines resistant to either cisplatin or doxorubicin. Br J Cancer 1993; 67:728-33.
44. Holroyde CP, Skutches CL, Boden G, Reichard GA. Glucose metabolism in cachectic patients with colorectal cancer. Cancer Res 1984;44:5910-3.
45. Holroyde CP, Gabuzda TC, Putnum RC. Carbohydrate metabolism in cancer cachexia. Cancer Treat Rep 1975;35:3710-4.
46. Lawson DH, Richmond A, Nixon DW, Rudman D. Metabolic approaches to cancer cachexia. Annu Rev Nutr 1982;2:277-301.
47. Moley JF, Morrison SQ, Norton JA. Insulin reversal of cancer cachexia in rats. Cancer Res 1985;45:4925-31.
48. Schilling J, Vranjes N, Fierez W, Joller H, Gyurech D, Ludwig E, et al. Clinical outcome and immunology of postoperative arginine, omega-3 fatty acids, and nucleotide-enriched enteral feeding: a randomized prospective comparison with standard enteral and low calorie/low fat IV solutions. Nutrition 1996;12:423-9.
49. Bower RH, Cerra FB, Bershadsky B, Licari JJ, Hoyt DB, Jensen GL, et al. Early enteral administration of a formula (Impact) supplemented with arginine, nucleotides and fish oil in intensive care unit patients: results of a multicenter, prospective, randomized, clinical trial. Crit Care Med 1995; 23:436-49.
50. Daly JM, Lieberman MD, Goldfine J, Shou J, Weintraub F, Rosato EF, et al. Enteral nutrition with supplemental arginine, RNA, and omega-3 fatty acids in patients after operation: immunologic, metabolic, and clinical outcome. Surgery 1992;112:56-67.
51. Boudreau MD, Chanmugam PS, Hart SB, Lee SH, Hwang DH. Lack of dose response by dietary n-3 fatty acids at a constant ratio of n-3 to n-6 fatty acids in suppressing eicosanoid biosynthesis from arachidonic acid. Am J Clin Nutr 1991;54:111-7.
52. Rioux FM, Innis SM, Dyer R, MacKinnon M. Diet-induced changes in liver and bile but not brain fatty acids can be predicted from differences in plasma phospholipid fatty acids in formula-and milk-fed piglets. Nutrition 1997;127: 370-7.
53. Vaughn DM, Reinhart GA, Swaim SF, Lauten SD, Garner CA, Boudreaux MK, et al. Evaluation of effects of dietary n-6 to n-3 fatty acid ratios on leukotriene B synthesis in dog skin and neutrophils. Vet Dermatol 1994;5:163-73.