Modulation of humoral and cell-mediated immune responses by dietary lutein in cats

Veterinary Immunology and Immunopathology

Volumn 73, Issue 3-4, 2000, Pages 331-341

  Kim, Hong Wook ^a   Chew, Boon P ^a   Wong, Teri S ^a   Park, Jean Soon ^a   Weng, Brian B C ^a   Byrne, Katherine M ^a   Hayek, Michael G ^b   Reinhart, Gregory A ^b  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b IAMS COMPANY   (United States)

Author keywords

Cats; DTH; Immunity; Lutein; Lymphocyte; Vaccine

Indexed keywords

ALPHA TOCOPHEROL; CD4 ANTIGEN; IMMUNOGLOBULIN G; INTERLEUKIN 2; PHYTOHEMAGGLUTININ; RETINOL; XANTHOPHYLL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CAT; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DOMESTIC ANIMAL; FEMALE; HUMORAL IMMUNITY; IMMUNITY; IMMUNOMODULATION; LYMPHOCYTE SUBPOPULATION; MONONUCLEAR CELL; NONHUMAN;

ANIMALS; ANTIBODY FORMATION; B-LYMPHOCYTES; CATS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLOW CYTOMETRY; HYPERSENSITIVITY, DELAYED; IMMUNITY, CELLULAR; IMMUNOGLOBULIN G; INTERLEUKIN-2; LUTEIN; LYMPHOCYTE ACTIVATION; MITOGENS; T-LYMPHOCYTES; VITAMIN A; VITAMIN E;

FELIS CATUS; PHYTOLACCACEAE;

EID: 0034654229     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(00)00152-5     Document Type: Article

References (24)

1. Ahmad B. The fate of carotene after absorption in the animal organism. Biochem. J. 25:1931;1195-1204.
2. Baker H., Schor S.M., Murphy B.D., DeAngelis B., Feingold S., Frank O. Blood vitamin and choline concentrations in healthy domestic cats, dogs, and horses. Am. J. Vet. Res. 47:1986;1468-1471.
3. Bendich A., Shapiro S.S. Effect of β-carotene and canthaxanthin on the immune responses of the rat. J. Nutr. 116:1986;2254-2262.
4. Britton G. Structure and properties of carotenoids in relation to function. FASEB J. 9:1995;1551-1558.
5. Chew B.P. Role of carotenoids in the immune response. J. Dairy Sci. 76:1993;2804-2811.
6. Chew B.P. Antioxidant vitamins affect food animal immunity and health. J. Nutr. 125:1995;1804S-1808S.
7. Chew B.P., Wong M.W., Wong T.S. Effects of lutein from marigold extract on immunity and growth of mammary tumors in mice. Anticancer Res. 16:1996;3689-3694.
8. Chew B.P., Weng B.C., Park J.S., Wong T.S., Combs R.L., Hayek M.G., Reinhart G.A. Uptake of β-carotene by plasma and lymphocytes in cats. FASEB J. 10:1997;A447.
9. Jyonouchi H., Zhang L., Tomita Y. Studies of immunomodulating actions of carotenoids. II. Astaxanthin enhances in vitro antibody production to T-dependent antigens without facilitating polyclonal B-cell activation. Nutr. Cancer. 19:1993;269-280.
10. Jyonouchi H., Zhang L., Gross M., Tomita Y. Immunomodulating actions of carotenoids: enhancement of in vivo and in vitro antibody production to T-dependent antigens. Nutr. Cancer. 21:1994;47-58.
11. Jyonouchi H., Sun S., Gross M. Effects of carotenoids on in vitro immunoglobulin production by human peripheral blood mononuclear cells: Astaxanthin, a carotenoid without vitamin A activity, enhances in vitro immunoglobulin production in response to a T-dependent stimulant and antigen. Nutr. Cancer. 23:1995;171-183.
12. Jyonouchi H., Sun S., Mizokami M., Gross M. Effects of various carotenoids on cloned, effector-stage T-helper cell activity. Nutr. Cancer. 26:1996;313-324.
13. Kim H.W., Chew B.P., Wong T.S., Park J.S., Weng B.C., Cerveny C.G., Byrne K.M., Hayek M.G., Reinhart G.A. Dietary lutein stimulates cell-mediated immune response in the canine. FASEB J. 12:1998;A966.
14. Mayne S.T. Beta-carotene, carotenoids and disease prevention in human. FASEB J. 10:1996;690-701.
15. Okai Y., Higashi-Okai K. Possible immunomodulating activities of carotenoids in in vitro cell culture experiments. Int. J. Immunopharmac. 18:1996;753-758.
16. Otto C.M., Brown C.A., Lindl P.A., Dawe D.L. Delayed hypersensitivity testing as a clinical measure of cell-mediated immunity in the cat. Vet. Immunol. Immunopathol. 38:1993;91-102.
17. Park J.S., Chew B.P., Wong T.S. Dietary lutein from marigold extract inhibits mammary tumor development in BALB/c mice. J. Nutr. 128:1998;1650-1656.
18. Park J.S., Chew B.P., Wong T.S., Weng B.C., Kim H.W., Hayek M.G., Reinhart G.A. Dietary lutein uptake by blood and leukocytes in domestic cats. FASEB J. 13:1999;A441.4.
19. Prabhala R.H., Maxey V., Hicks M.J., Watson R.R. Enhancement of the expression of activation markers on human peripheral blood mononuclear cells by in vitro culture with retinoids and carotenoids. J. Leuk. Biol. 45:1989;249-254.
20. Prabhala R.H., Garewal H.S., Hicks M.J., Sampliner R.E., Watson R.R. The effects of 13-cis-retinoic acid and beta-carotene on cellular immunity in humans. Cancer. 67:1991;1556-1560.
21. SAS, 1991. SAS/STAT User's Guide. SAS Institute Inc., Cary, NC.
22. Slifka K.A., Bowen P.E., Stacewicz-Sapuntzakis M., Crissey S.D. A survey of serum and dietary carotenoids in captive wild animals. J. Nutr. 129:1999;380-390.
23. Watson R.R., Prabhala R.H., Plezia P.M., Alberts D.S. Effect of β-carotene on lymphocyte subpopulations in elderly humans: evidence for a dose-response relationship. Am. J. Clin. Nutr. 53:1991;90-94.
24. Weng B.C., Chew B.P., Park J.S., Wong T.S., Combs R.L., Hayek M.G., Reinhart G.A. β-Carotene uptake by blood plasma and leukocytes in dogs. FASEB J. 10:1997;A447.