Wild-type and mutant forms of v-src differentially alter neuronal migration and differentiation in vivo

Journal of Neuroscience Research

Volumn 59, Issue 2, 2000, Pages 226-237

  Morgan, John C ^a,c   Majors, John E ^b   Galileo, Deni S ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA MEDICAL CENTER   (United States)

Author keywords

Chick embryo; Optic tectum; Retroviral vector; Tyrosine kinase; V src

Indexed keywords

PROTEIN TYROSINE KINASE; VIRUS VECTOR;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN DEVELOPMENT; CELL CLONE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CHICKEN; CONTROLLED STUDY; EMBRYO; ENZYME ANALYSIS; NERVE CELL; NONHUMAN; OPTIC TECTUM; PRIORITY JOURNAL;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CHICK EMBRYO; CLONE CELLS; GENE DELETION; GENE EXPRESSION REGULATION, VIRAL; GENES, SRC; GENETIC VECTORS; MUTAGENESIS; NEURONS; PHENOTYPE; PHOSPHOTYROSINE; PROTEIN-TYROSINE KINASES; RETROVIRIDAE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; SUPERIOR COLLICULUS;

EID: 0034651004     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(20000115)59:2<226::AID-JNR9>3.0.CO;2-J     Document Type: Article

References (55)

1. Aguzzi A, Kleihues P, Heckl K, Wiestler OD. 1991. Cell type-specific tumor induction in neural transplants by retrovirus-mediated oncogene transfer. Oncogene 6:113-118.
2. Bennett G, DiLullo C. 1985. Transient expression of a neurofilament protein by replicating neuroepithelial cells of the embryonic chick brain. Dev Biol 107:107-127.
3. Booth CJ, Sundberg JP. 1995. Hemangiomas and hemangiosarcomas in inbred laboratory mice. Lab Anim Sci 45:497-502.
4. Brackenbury R, Greenberg ME, Edelman GM. 1984. Phenotypic changes and loss of N-CAM-mediated adhesion in transformed embryonic chicken retinal cells. J Cell Biol 99:1944-1954.
5. v-src are not essential for stimulation of cell proliferation. J Virol 61:1678-1681.
6. Clark EA, Brugge JS. 1995. Integrins and signal transduction pathways: the road taken. Science 268:233-239.
7. v-src. Mol Cell Biol 5:2753-2763.
8. src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene. Mol Cell Biol 5:2789-2795.
9. Fincham VJ, Frame MC. 1998. The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility. EMBO J 17:81-92.
10. Fincham VJ, Wyke JA, Frame MC. 1995. v-src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts. Oncogene 10:2247-2252.
11. Foellmer HG, Kawahara K, Madri JA, Furthmayr H, Timpl R, Tuderman L. 1983. A monoclonal antibody specific for the amino terminal cleavage site of procollagen type I. Eur J Biochem 134:183-189.
12. Galileo DS, Gray GE, Owens GC, Majors J, Sanes JR. 1990. Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies. Proc Natl Acad Sci USA 87:458-462.
13. Galileo DS, Gee AP, Linser PJ. 1991. Neurons are replenished in cultures of embryonic chick optic tectum after immunomagnetic depletion. Dev Biol 146:278-291.
14. Galileo DS, Majors J, Horwitz AF, Sanes JR. 1992. Retrovirally introduced antisense integrin RNA inhibits neuroblast migration in vivo. Neuron 9:1117-1131.
15. Ghattas IR, Sanes JR, Majors JE. 1991. The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos. Mol Cell Biol 11:5848-5859.
16. Gillet G, Guerin M, Trembleau A, Brun G. 1995. A BCL-2-related gene is activated in avian cells transformed by the Rous sarcoma virus. EMBO J 14:1372-1381.
17. Gray GE, Sanes JR. 1991. Migratory paths and phenotypic choices of clonally related cells in the avian optic tectum. Neuron 6:211-225.
18. Gray GE, Sanes JR. 1992. Lineage of radial glia in the chicken optic tectum. Development 114:271-283.
19. Gray GE, Glover JC, Majors J, Sanes JR. 1988. Radial arrangement of clonally related cells in the chicken optic tectum: lineage analysis with a recombinant retrovirus. Proc Natl Acad Sci USA 85:7356-7360.
20. Haltmeier H, Rohrer H. 1990. Distinct and different effects of the oncogenes v-myc and v-src on avian sympathetic neurons: retroviral transfer of v-myc stimulates neuronal proliferation whereas v-src transfer enhances neuronal differentiation. J Cell Biol 10:2087-2098.
21. v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J 12:307-314.
22. Hamburger V, Hamilton HL. 1951. A series of normal stages in the development of the chick embryo. J Morphol 88:49-92.
23. Herman JP, Victor JC, Sanes JR. 1993. Developmentally regulated and spatially restricted antigens of radial glial cells. Dev Dynam 197:307-318.
24. Howell BW, Gertler FB, Cooper JA. 1997a. Mouse disabled (mDab1): a Src binding protein implicated in neuronal development. EMBO J 16:121-132.
25. Howell BW, Hawkes R, Soriano P, Cooper JA. 1997b. Neuronal position in the developing mouse brain is regulated by mouse diabled-1. Nature 389:733-737.
26. Ignelzi MA Jr, Miller DR, Soriano P, Maness PF. 1994. Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1. Neuron 12:873-884.
27. Imamoto A, Soriano P. 1993. Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell 73:1117-1124.
28. Keane RW, Lipsich LA, Brugge JS. 1984. Differentiation and transformation of neural plate cells. Dev Biol 103:38-52.
29. Kroger S, Schwarz U. 1990. The avian tectobulbar tract: development, explant culture and effects of antibodies on the pattern of neurite out-growth. J Neurosci 10:3118-3134.
30. Linser PJ, Perkins M. 1987. Gliogenesis in the embryonic avian optic tectum: neuronal - glial interactions influence astroglial phenotype maturation. Dev Brain Res 31:277-290.
31. Maness P. 1992. Nonreceptor protein tyrosine kinases associated with neuronal development. Dev Neurosci 14:257-270.
32. Mangeney M, Schmitt J-R, Leverrier Y, Thomas J, Marvel J, Brun G, Gillet G. 1996. The product of the v-src-inducible gene nr-13 is a potent anti-apoptotic factor. Oncogene 13:1441-1446.
33. Martin de las Mulas J, Espinosa de los Monteras A, Carrasco L, van Niel M, Fernandez A. 1995. Immunohistochemical distribution pattern of intermediate filament proteins in 50 feline neoplasms. Vet Pathol 32:692-701.
34. Morse WR, Whitesides JG 3rd, LaMantia AS, Maness PF. 1998. p59fyn And pp60c-src modulate axonal guidance in the developing mouse olfactory pathway. J Neurobiol 36:53-63.
35. Nada S, Yagi T, Takeda H, Tokunaga T, Nakagawa H, Ikawa Y, Okada M, Aizawa S. 1993. Constitutive activation of Src family kinases in mouse embryos that lack Csk. Cell 73:1125-1135.
36. Okamura H, Resh MD. 1995. p80/85 cortactin associates with the Src SH2 domain and colocalizes with v-src in transformed cells. J Biol Chem 270:26613-26618.
37. Ono K, Tomasiewicz H, Magnuson T, Rutishauser U. 1994. N-CAM mutation inhibits tangential neuronal migration and is phenocopied by enzymatic removal of polysialic acid. Neuron 13:595-609.
38. Orchard GE, Zelger B, Jones EW, Jones RR. 1996. An immunocytochemical assessment of 19 cases of cutaneous angiosarcoma. Histopathology 28:235-240.
39. Pessac B, Calothy G. 1974. Transformation of chick embryo neuroretinal cells by Rous sarcoma virus in vitro: induction of cell proliferation. Science 185:709-710.
40. Rakic P. 1990. Principles of neuronal cell migration. Experientia 46:882-891.
41. Rakic P, Cameron RS, Komuro H. 1994. Recognition, adhesion, transmembrane signaling and cell motility in guided neuronal migration. Curr Opin Neurobiol 4:63-69.
42. Rausch DM, Dickens G, Doll S, Fujita K, Koizumi S, Rudkin BB, Tocco M, Eiden LE, Guroff G. 1989. Differentiation of PC12 cells with v-src: comparison with nerve growth factor. J Neurosci Res 24:49-58.
43. Raymond VW, Parsons JT. 1987. Identification of an amino terminal domain required for the transforming activity of the Rous sarcoma virus src protein. Virology 160:400-410.
44. Roncali L, Ribatti D, Ambrosi G. 1985. Vasculogenesis in the chick embryo optic tectum. Acta Anat 122:229-234.
45. Soriano P, Montogomery C, Geske R, Bradley A. 1991. Targeted disruption of the c-src protooncogene leads to osteopetrosis in mice. Cell 64:693-702.
46. Stoker AW, Hatier C, Bissell MJ. 1990. The embryonic environment strongly attenuates v-src oncogenesis in mesenchymal and epithelial tissues, but not endotheha. J Cell Biol 111:217-228.
47. Vardimon L, Fox LE, Cohen-Kupiec R, Degenstein L, Moscona AA. 1991. Expression of v-src in embryonic neural retina alters cell adhesion, inhibits histogenesis and prevents induction of glutamine synthetase. Mol Cell Biol 11:5275-7284.
48. v-src inactivate transformation and modulate membrane stability. J Virol 63:291-302.
49. Weissenberger J, Steinbach JP, Malin G, Spada S, Rülicke T, Aguzzi A. 1997. Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice. Oncogene 14:2005-2013.
50. v-src do not phosphorylate proteins of 120-150 kDa. Oncogene 4:231-236.
51. v-src kinase-induced cell death. Oncogene 11:1459-1468.
52. Yagi T. 1994. Src family kinases control neural development and function. Dev Growth Differ 36:543-550.
53. Yamagata M, Herman JP, Sanes JR. 1995. Lamina-specific expression of adhesion molecules in developing chick optic tectum. J Neurosci 15: 4556-4571.
54. Zhang Z, Galileo DS. 1998a. Retroviral transfer of antisense integrin α6 or α8 sequences results in laminar redistribution or clonal cell death in developing brain. J Neurosci 189:6928-6938.
55. Zhang Z, Galileo DS. 1998b. Widespread programmed cell death in early developing chick optic tectum. Neuroreport 9:2797-2801.