Binding properties of [3H]MS-377, a novel σ receptor ligand, to rat brain membranes

European Journal of Pharmacology

Volumn 400, Issue 1, 2000, Pages 51-57

  Karasawa, Jun ichi ^a   Takahashi, Shinji ^a   Horikomi, Kazutoshi ^a  

^a Institute of Biological Science Mitsui Pharmaceuticals Inc   (Japan)

Author keywords

Brain membrane, rat; MS 377; Radiolabeled ligand binding; Binding site

Indexed keywords

1 (4 CHLOROPHENYL) 3 [4 (2 METHOXYETHYL)PIPERAZIN 1 YL] METHYL 2 PYRROLIDINONE TARTRATE; 1,3 BIS(2 METHYLPHENYL)GUANIDINE; ALPHA (4 FLUOROPHENYL) 4 (5 FLUORO 2 PYRIMIDINYL) 1 PIPERAZINEBUTANOL; COCAINE; HALOPERIDOL; MS 377; N ALLYLNORMETAZOCINE; PENTAZOCINE; PHENCYCLIDINE; SIGMA OPIATE RECEPTOR; SIGMA RECEPTOR LIGAND; UNCLASSIFIED DRUG; 1 (4 CHLOROPHENYL) 3 (4 (2 METHOXYETHYL) PIPERAZIN 1 YL)METHYL 2 PYRROLIDINONE TARTRATE; 1-(4-CHLOROPHENYL)-3-(4-(2-METHOXYETHYL) PIPERAZIN-1-YL)METHYL-2-PYRROLIDINONE TARTRATE; LIGAND; NEUROLEPTIC AGENT; PIPERAZINE DERIVATIVE; PYRROLIDINE DERIVATIVE; TARTARIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GUINEA PIG; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SCATCHARD PLOT; SCHIZOPHRENIA; STEREOISOMERISM; ANIMAL; BINDING COMPETITION; BRAIN; METABOLISM; WISTAR RAT;

ANIMALS; ANTIPSYCHOTIC AGENTS; BINDING SITES; BINDING, COMPETITIVE; BRAIN; LIGANDS; MALE; PIPERAZINES; PYRROLIDINES; RATS; RATS, WISTAR; RECEPTORS, SIGMA; TARTRATES;

EID: 0034647337     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00348-4     Document Type: Article

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