Is there tonic activity in the endogenous opioid systems? A c-Fos study in the rat central nervous system after intravenous injection of naloxone or naloxone-methiodide

Journal of Comparative Neurology

Volumn 427, Issue 2, 2000, Pages 285-301

  Gestreau, Christian ^a   Guen, Stéphanie Le ^a   Besson, Jean Marie ^a  

^a PSL RESEARCH UNIVERSITY   (France)

Author keywords

c Fos protein; Cardiorespiratory functions; Endogenous opioids; Immunohistochemistry; Opioid receptors

Indexed keywords

17 METHYLNALOXONE; AVIDIN; BIOTIN; ENDORPHIN; NALOXONE; OPIATE ANTAGONIST; OPIATE RECEPTOR; PROTEIN C FOS;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN; BRAIN REGION; CONTROLLED STUDY; EMOTION; HEART FUNCTION; IMMUNOHISTOCHEMISTRY; LEARNING; LUMBOSACRAL SPINE; MALE; MYOTONIA; NERVE CELL; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY FUNCTION; SOLITARY TRACT NUCLEUS;

ANIMALS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM; MALE; NALOXONE; NERVE NET; NEURAL INHIBITION; NEURONS; OPIOID PEPTIDES; PROTO-ONCOGENE PROTEINS C-FOS; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034645384     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9861(20001113)427:2<285::AID-CNE9>3.0.CO;2-T     Document Type: Article

References (109)

1. Blockade of acquisition of drug-conditioned place preference
2. Reciprocal connections between nucleus tractus solitarii and rostral ventrolateral medulla
3. The relationships between temporal lobe and diencephalic structures implicated in anterograde amnesia
4. Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist
5. Endogenous opioids: Biology and function
6. Endogenous opioids: Overview and current issues
7. Viscerotopic representation of the upper alimentary tract in the rat: Sensory ganglia and nuclei of the solitary and spinal trigeminal tracts
8. Rewarding properties of beta-endorphin as measured by place-preference
9. Naltrexone-induced hypothermia in the rat
10. Interactions of endogenous opioid and excitatory amino acid inputs to the caudal ventrolateral medulla of the rat
11. Cellular localization and distribution of the cloned mu and kappa opioid receptors in rat gastrointestinal tract
12. Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated
13. Central control of breathing in mammals: Neuronal circuitry, membrane properties, and neurotransmitters
14. Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats
15. Area postrema and aortic or vagal afferents converge to excite cells in nucleus tractus solitarius
16. Area postrema: Chemoreceptor circumventricular organ of the medulla oblongata
17. Stress induces Fos expression in neurons of the thalamic paraventricular nucleus that innervate limbic forebrain sites
18. Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear
19. Rostral ventrolateral medullary opioid receptor activation modulates presser response to muscle contraction
20. Neuroanatomical patterns of Fos-like immunoreactivity induced by naltrexone in food-restricted and ad libitum fed rats
21. Differential effects of mu and kappa opioid antagonists on Fos-like immunoreactivity in extended amygdala
22. Organization and transmitter specificity of medullary neurons activated by sustained hypertension: Implications for understanding baroreceptor reflex circuitry
23. Pharmacological studies of nociceptive systems using the c-Fos immunohistochemical technique: An indicator of noxiously activated spinal neurons
24. Opioid-receptor coupled second messenger systems
25. Collateral axonal projections from ventrolateral medullary non-catecholaminergic neurons to central nucleus of the amygdala
26. Receptor localization in the mammalian dorsal horn and primary afferent neurons
27. Pattern and time course of immediate early gene expression in rat brain following acute stress
28. Functional organization of central pathways regulating the cardiovascular system
29. Role of opioid peptides in brain mechanisms regulating blood pressure
30. Effects of opiates and methionine-enkephalin on pontine and bulbar respiratory neurons of the cat
31. Immunohistochemical localization of mu-opioid receptors in the central nervous system of the rat
32. Co-localization of mu-opioid receptor-like immunoreactivity with substance P-LI, calcitonin gene-related peptide-LI and nitric-oxide synthase-LI in vagal and glossopharyngeal afferent neurons of the rat
33. Endogenous opioids tonically inhibit the depressor neurones in the caudal ventrolateral medulla of rabbits: Mediation through delta- and kappa-receptors
34. Experimental endotoxin shock: The pathophysiologic function of endorphins and treatment with opiate antagonists
35. Naloxone fails to alter local cerebral glucose utilization in the rat
36. Endogenous opiates and chemical control of breathing in humans
37. Respiratory and cardiovascular effects of met-enkephalin applied to the ventral surface of the brain stem
38. Effects of heroin and naloxone on cerebral blood flow in the conscious rat
39. Differential brainstem Fos-like immunoreactivity after laryngeal-induced coughing and its reduction by codeine
40. Is there a tonic activity of the endogenous opioid systems at various supraspinal levels: A c-Fos study after intravenous injection of naloxone or selective opioid-receptor antagonists
41. Site-directed alkylation of multiple opioid receptors. II. Pharmacological selectivity
42. Opioids and central baroreflex control: A site of action in the nucleus tractus solitarius
43. Endorphins: 'Opiates for the masses'
44. Role of the ventral medulla oblongata in blood pressure regulation
45. Rostral ventrolateral medulla and sympathorespiratory integration in rats
46. Evidence for direct projections from the nucleus of the solitary tract onto medullary adrenaline cells
47. Mu-opioid receptors in NTS elicit pressor responses via sympathetic pathways
48. Pre- and post-synaptic inhibitory actions of methionine-enkephalin on identified bulbospinal neurons of the rat RVL
49. Inducible and constitutive transcription factors in the mammalian nervous system: Control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
50. Naloxone induces multiple effects on aversive Pavlovian conditioning in rabbits
51. Cardiovascular effects of endogenous opiate systems
52. In vivo receptor occupation by opiates and correlation to the pharmacological effect
53. Intracerebroventricular administration of corticotropin-releasing factor induces c-fos mRNA expression in brain regions related to stress responses: Comparison with pattern of c-fos mRNA induction after stress
54. Site-directed alkylation of multiple opioid receptors. I. Binding selectivity
55. Opioids suppress spontaneous and NMDA-induced inhibitory post-synaptic potentials in the dorsal raphe nucleus of the rat in vitro
56. Efferent ACTH-IR opiocortin projections from nucleus tractus solitarius: A hypothalamic deafferentation study
57. Endogenous opioid systems in the modulation of pain: Behavioral studies in rat models of persistent hyperalgesia
58. Glucose utilization in the rat brain during chronic morphine treatment and naloxone-precipitated morphine withdrawal
59. Opponent process theory of motivation: Neurobiological evidence from studies of opiate dependence
60. Naloxone alters the local metabolic rate for glucose in discrete brain regions associated with opiate withdrawal
61. The role of opioid peptides in cardiovascular regulation. New developments in the treatment of shock?
62. Neurochemical modulation of cardiovascular control in the nucleus tractus solitarius
63. Naloxone impairs spatial performance in rats
64. Effects of naloxone and thyrotropin-releasing hormone on plasma catecholamines, corticosterone, and arterial pressure in normal and endotoxemic rats
65. Endogenous opioid peptides: Multiple agonists and receptors
66. Anatomy of CNS opioid receptors
67. Immunohistochemical localization of the cloned kappa 1 receptor in the rat CNS and pituitary
68. Quaternary naloxone blocks morphine analgesia in spinal but not intact rats
69. The effects of the naltrexone implant on rodent social interactions and cocaine-induced conditioned place preference
70. Neuronal expression of Fos protein in the rat brain after baroreceptor stimulation
71. Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun
72. Cardiovascular effects of opioid antagonist naloxone in rostral ventrolateral medulla of rabbits
73. Aversive properties of naloxone in non-dependent (naive) rats may involve blockade of central betaendorphin
74. Localization of mu-opioid receptor-like immunoreactivity in the central components of the vagus nerve: A light and electron microscope study in the rat
75. Opioid actions on membrane ion channels
76. Opiate antagonist, naloxone, strongly reduces analgesia induced by stimulation of a raphe nucleus (centrahs inferior)
77. Endogenous opiates: 1997
78. Neuroanatomical patterns of Fos-like immunoreactivity induced by a palatable meal and meal-paired environment in saline- and naltrexone-treated rats
79. Brain transcription factor expression: Effects of acute and chronic amphetamine and injection stress
80. Branching projections of catecholaminergic brainstem neurons to the paraventricular hypothalamic nucleus and the central nucleus of the amygdala in the rat
81. Presence of mu-opioid receptors in targets of efferent projections from the central nucleus of the amygdala to the nucleus of the solitary tract
82. Interaction of the hypothalamic paraventricular nucleus and central nucleus of the amygdala in naloxone blockade of neuropeptide Y-induced feeding revealed by c-fos expression
83. Cardiovascular response to injections of enkephalin in the pressor area of the ventrolateral medulla
84. Opioid peptides and central control of blood pressure
85. PreBotzinger complex and pacemaker neurons: Hypothesized site and kernel for respiratory rhythm generation
86. Role of endogenous opioids and serotonin in the hemodynamic response to hemorrhage during hypoxia
87. Selective opioid agonists modulate afferent transmission in the rat nucleus tractus solitarius
88. Mechanism of inhibition of calcium channels in rat nucleus tractus solitarius by neurotransmitters
89. Neuropeptides and catecholamines in efferent projections of the nuclei of the solitary tract in the rat
90. Innervation of the amygdaloid complex by catecholaminergic cell groups of the ventrolateral medulla
91. Role of enkephalins in ventrolateral medullary control of blood pressure
92. Endogenous opioids modulate ventilation in the obese Zucker rat
93. Effects of naloxone on oxygen consumption and ventilation in awake golden Syrian hamsters
94. Naloxone microinjected into the arcuate nucleus has differential effects on ventilation in male and female rats
95. Efferents of the opiocortin-containing region of the commissural nucleus tractus solitarius
96. Pharmacokinetics of naloxone in rats
97. Naloxone does not affect ventilatory responses to hypoxia and hypercapnia in rats
98. Central effects of opioid agonists and naloxone on blood pressure and heart rate in normotensive and hypertensive rats
99. Endogenous opiates and the pathogenesis of hypertension
100. Mammillothalamic tracts and representational memory
101. The role of dorsal respiratory group neurons studied with cross-correlation in the decerebrate rat
102. Role of proprioception in the control of lid position during reflex and conditioned blink responses in the alert behaving cat
103. Naloxone blockade of amphetamine place preference conditioning
104. Changes in striatal neuropeptides and GAD67 expression following a minimal cortical lesion
105. The organization of projections from the central nucleus of the amygdala to brainstem sites involved in central autonomic regulation: A combined retrograde transport-immunohistochemical study
106. Naloxone administration and ventilation in awake cats
107. Study of naloxone in normal awake man: Effects on heart rate and respiration
108. Hypertensive response following stimulation of opiate receptors in the caudal ventrolateral medulla