Kindling causes persistent in vivo changes in firing rates and glutamate sensitivity of central piriform cortex neurons in rats

Neuroscience

Volumn 99, Issue 2, 2000, Pages 217-227

  Gernert, M ^a   Bloms Funke, P ^a   Ebert, U ^a   Loscher W ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Amygdala; Epilepsy; GABA; Seizures

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID;

AMYGDALOID NUCLEUS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FACILITATION; FEMALE; INTERNEURON; KINDLING; NERVE EXCITABILITY; NERVE POTENTIAL; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT;

ACTION POTENTIALS; AMYGDALA; ANIMALS; EXCITATORY AMINO ACID AGONISTS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; KINDLING, NEUROLOGIC; N-METHYLASPARTATE; NEURONS; RATS; RATS, WISTAR;

EID: 0034638269     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00195-0     Document Type: Article

References (56)

1. Adams J.C. Heavy metal intensification of DAB-based HRP reaction product. J. Histochem. Cytochem. 29:1981;775.
2. Blackwood D.H.R., Martin M.J., McQueen J.K. Enhanced rate of kindling after prolonged electrode implantation into the amygdala of rats. J. Neurosci. Meth. 5:1982;343-348.
3. Bloms-Funke P., Gernert M., Ebert U., Löscher W. Extracellular single-unit recordings of piriform cortex neurons in rats: influence of different types of anesthesia and characterization of neurons by pharmacological manipulation of serotonin receptors. J. Neurosci. Res. 55:1999;608-619.
4. Bloms-Funke P., Löscher W. The anticonvulsant gabapentin decreases firing rates of substantia nigra pars reticulata neurons. Eur. J. Pharmac. 316:1996;211-218.
5. Boast C.A., Reid S.A., Johnson P., Zornetzer S.F. A caution to brain scientists: unsuspected hemorrhagic vascular damage resulting from mere electrode implantation. Brain Res. 103:1976;527-534.
6. Bonhaus D.W., Walters J.R., McNamara J.O. Activation of substantia nigra neurons: role in the propagation of seizures in kindled rats. J. Neurosci. 6:1986;3024-3030.
7. Burnham W. M. and Cottrell G. A. (1990) The GABA hypothesis of kindling. In Kindling 4 (ed. Wada J. A.). Plenum, New York.
8. Cain D. P. (1986) The transfer phenomenon in kindling. In Kindling 3 (ed. Wada J. A.). Raven, New York.
9. Gale K. Progression and generalization of seizure discharge: anatomical and neurochemical substrates. Epilepsia. 29:(Suppl. 2):1988;S15-S34.
10. Gellman R.L., Aghajanian G.K. Pyramidal cells in piriform cortex receive a convergence of inputs from monoamine activated GABAergic interneurons. Brain Res. 600:1993;63-73.
11. Goddard G. V., Dragunov M., Maru E. and Macleod E. K. (1986) Kindling and the forces that oppose it. In The Limbic System: Functional Organization and Clinical Disorders (eds Doane B. K. and Livingston K. E.). Raven, New York.
12. Guyenet P.G., Aghajanian G.K. Antidromic identification of dopaminergic and other output neurons of the rat substantia nigra. Brain Res. 150:1978;69-84.
13. Haberly L.B., Bower J.M. Olfactory cortex: model circuit for study of associative memory? Trends Neurosci. 12:1989;258-264.
14. Haberly L.B., Price J.L. Association and commissural fiber systems of the olfactory cortex of the rat. I. Systems originating in the piriform cortex and adjacent areas. J. comp. Neurol. 178:1978;711-740.
15. Haberly L.B., Sutula T.P. Neuronal processes that underlie expression of kindled epileptiform events in the piriform cortex in vivo. J. Neurosci. 12:1992;2211-2224.
16. Hoffman W.H., Haberly L.B. Kindling-induced epileptiform potentials in piriform cortex slices originate in the underlying endopiriform nucleus. J. Neurophysiol. 76:1996;1430-1438.
17. Hönack D., Wahnschaffe U., Löscher W. Kindling from stimulation of a highly sensitive locus in the posterior part of the piriform cortex. Comparison with amygdala kindling and effects of antiepileptic drugs. Brain Res. 538:1991;196-202.
18. Lehmann H., Ebert U., Löscher W. Amygdala-kindling induces a lasting reduction of GABA-immunoreactive neurons in a discrete area of the ipsilateral piriform cortex. Synapse. 29:1998;299-309.
19. Löscher W., Hörstermann D., Hönack D., Rundfeldt C., Wahnschaffe U. Transmitter amino acid levels in rat brain regions after amygdala-kindling or chronic electrode implantation without kindling: evidence for a pro-kindling effect of prolonged electrode implantation. Neurochem. Res. 18:1993;775-781.
20. Löscher W., Ebert U., Wahnschaffe U., Rundfeldt C. Susceptibility of different cell layers of the anterior and posterior part of the piriform cortex to electrical stimulation and kindling: comparison with the basolateral amygdala and "area tempestas" Neuroscience. 66:1995;265-276.
21. Löscher W., Rohlfs A., Rundfeldt C. Reduction in firing rate of substantia nigra pars reticulata neurons by valproate: influence of different types of anesthesia in rats. Brain Res. 702:1995;133-144.
22. Löscher W., Wahnschaffe U., Hönack D., Rundfeldt C. Does prolonged implantation of depth electrodes predispose the brain to kindling? Brain Res. 697:1995;197-204.
23. Löscher W., Wlaz P., Ebert U. Microinjections of bicuculline induce generalized seizures in the anterior and posterior part of the piriform cortex in the rat. Soc. Neurosci. Abstr. 23:1997;2152.
24. Löscher W., Lehmann H., Ebert U. Differences in the distribution of GABA- and GAD-immunoreactive neurons in the anterior and posterior piriform cortex of rats. Brain Res. 800:1998;21-31.
25. Löscher W., Hönack D., Gramer M. Effect of depth electrode implantation with or without subsequent kindling on GABA turnover in various rat brain regions. Epilepsy Res. 37:1999;95-108.
26. Löscher W., Ebert U. Basic mechanisms of seizure propagation: targets for rational drug design and rational polypharmacy. Epilepsy Res. Suppl. 11:1996;17-44.
27. Löscher W., Ebert U. The role of the piriform cortex in kindling. Prog. Neurobiol. 50:1996;427-481.
28. 2A receptor antagonist. Eur. J. Pharmac. 259:1994;137-141.
29. McIntyre D. C. (1986) Kindling and the pyriform cortex. In Kindling 3 (ed. Wada J. A.). Raven, New York.
30. McIntyre D. C. and Kelly M. E. (1990) Is the pyriform cortex important for limbic kindling? In Kindling 4 (ed. Wada J. A.). Plenum, New York.
31. McIntyre D.C., Plant J.R. Pyriform cortex involvement in kindling. Neurosci. Biobehav. Rev. 13:1989;277-280.
32. McIntyre D.C., Plant J.R. Long-lasting changes in the origin of spontaneous discharges from amygdala-kindled rats - piriform vs. perirhinal cortex in vitro. Brain Res. 624:1993;268-276.
33. 1C receptor mRNA in the rodent brain examined by in situ hybridization histochemistry: comparison with receptor binding distribution. Neuroscience. 35:1990;577-591.
34. 2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites. Brain Res. 524:1990;139-143.
35. Niespodziany I., Klitgaard H., Margineanu D.G. Chronic electrode implantation entails epileptiform field potentials in rat hippocampal slices, similarly to amygdala kindling. Epilepsy Res. 36:1999;69-74.
36. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 4th :1998;Academic Press, Sydney.
37. Pellegrino L.J., Cushman A.J. A Stereotaxic Atlas of the Rat Brain. 1967;Appleton-Century-Crofts, New York.
38. Piredda S., Gale K. A crucial epileptogenic site in the deep prepiriform cortex. Nature. 317:1985;623-625.
39. Piredda S., Lim C.R., Gale K. Intracerebral site of convulsant action of bicuculline. Life Sci. 36:1985;1295-1298.
40. Prince H.K., Conn P.J., Blackstone C.D., Huganir R.L., Levey A.I. Down-regulation of AMPA receptor subunit GluR2 in amygdaloid kindling. J. Neurochem. 64:1995;462-465.
41. Racine R.J. Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroenceph. clin. Neurophysiol. 32:1972;281-294.
42. Racine R.J., Moore K.A., Evans C. Kindling-induced potentiation in the piriform cortex. Brain Res. 556:1991;218-225.
43. Rohlfs A., Rundfeldt C., Koch R., Löscher W. A comparison of the effects of valproate and its major active metabolite E-2-en-valproate on single unit activity of substantia nigra pars reticulata neurons in rats. J. Pharmac. exp. Ther. 277:1996;1305-1314.
44. Rohlfs A., Nikkhah G., Rosenthal C., Rundfeldt C., Brandis A., Samii M., Löscher W. Hemispheric asymmetries in spontaneous firing characteristics of substantia nigra pars reticulata neurons following a unilateral 6-hydroxydopamine lesion of the rat nigrostriatal pathway. Brain Res. 761:1997;352-356.
45. Rosen A.D., Frumin N.V. Focal epileptogenesis after intracortical hemoglobin injection. Expl Neurol. 66:1979;277-284.
46. Schwabe K., Ebert U., Löscher W. Effect of selective bilateral lesions of different parts of the piriform cortex on amygdala kindling in rats. Soc. Neurosci. Abstr. 25:1999;1608.
47. Schwob J.E., Haberly L.B., Price J.L. The development of physiological responses of the piriform cortex in rats to stimulation of the lateral olfactory tract. J. comp. Neurol. 223:1984;223-237.
48. 2-activated interneuron. Brain Res. 506:1990;62-69.
49. 2 receptors in interneurons. Synapse. 9:1991;208-218.
50. Shipley M. T., McLean J. H. and Ennis M. (1995) The olfactory system. In The Rat Nervous System (ed. Paxinos G.). Academic, San Diego.
51. Simons D.J., Land P.W.A. A reliable technique for marking the location of extracellular recording sites using glass micropipettes. Neurosci. Lett. 81:1987;100-104.
52. Teskey G.C., Racine R.J. Increased spontaneous unit discharge rates following electrical kindling in the rat. Brain Res. 624:1993;11-18.
53. Waszczak B.L., Eng N., Walters J.R. Effects of muscimol and picrotoxin on single unit activity of substantia nigra neurons. Brain Res. 188:1980;185-197.
54. Waszczak B.L., Lee E.K., Walters J.R. Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons. J. Pharmac. exp. Ther. 239:1986;606-611.
55. Waszczak B.L., Applegate C.D., Burchfiel J.L. Kindling does not cause persistent changes in firing rates or transmitter sensitivities of substantia nigra pars reticulata neurons. Brain Res. 455:1988;115-122.
56. Willmore L.J., Sypert G.W., Munson J.B., Hurd R.W. Chronic focal epileptiform discharges induced by injection of iron into rat and cat cortex. Science. 200:1978;1501-1502.