Cocaine abusers show a blunted response to alcohol intoxication in limbic brain regions

Life Sciences

Volumn 66, Issue 12, 2000, Pages PL161-PL167

  Volkow, Nora D ^a,b   Wang, Gene Jack ^a   Fowler, Joanna S ^a   Franceschi, Dinko ^a   Thanos, Panayotis K ^a,b   Wong, Christopher ^a   Gatley, Samuel J ^a   Ding, Yu Shin ^a   Molina, Patricia ^a,c   Schlyer, David ^a   Alexoff, David ^a   Hitzemann, Robert ^b   Pappas, Naomi ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain glucose metabolism; Drug addiction; Neurotoxicity; Positron emission tomography; Reward

Indexed keywords

ALCOHOL; BENZODIAZEPINE DERIVATIVE; COCAINE; GLUCOSE;

ADULT; ALCOHOL BLOOD LEVEL; ALCOHOL INTOXICATION; ARTICLE; BRAIN REGION; CLINICAL ARTICLE; CLINICAL FEATURE; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG SENSITIVITY; GABAERGIC TRANSMISSION; GLUCOSE UTILIZATION; HUMAN; LIMBIC CORTEX;

EID: 0034635572     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0024-3205(00)00421-5     Document Type: Article

References (24)

1. 1. B.F. Grant, and T.C. Harford, Drug & Alcohol Dependence 25 97-104 (1990).
2. 2. F. Boag and C.W.H. Havard, Postgrad Med J 61 997-999 (1985).
3. 3. B.F. Sands and D.A. Ciraulo, Cocaine drug-drug interactions. J Clin Psychopharm 12 49-55 (1992).
4. 4. N.D. Volkow, G.-J. Wang, J.S. Fowler, R. Hitzemann, S.J. Gatley, S.L. Dewey and N. Pappas, Am J Psychiatry 155 200-206 (1998).
5. 5. R.A. Harris, S.J. Mihic and C.F. Valenzuela, Drug Alcohol Depend 51 155-164 (1998).
6. 6. N.D. Volkow, G.-J. Wang, R. Hitzemann, J.S. Fowler, A.P. Wolf, N. Pappas, A. Biegon and S.L. Dewey, Am J Psychiatry 150 417-422 (1993).
7. 7. B.P. Lloyd, P. Burrin, P. Smythe and K.G.M.M. Alberti, Clin Chem 24 1724-1729 (1978).
8. 8. J. Talairach and P. Tournoux, A Co-planar Stereotaxic Atlas of a Human Brain. Thieme, New York (1988).
9. 9. D.B. Pritchett, B.D. Sontheime, S. Shivers, S. Ymer, H. Kettenmann, P.R. Schofield and P.H. Seeburg, Nature 338 582-584 (1989).
10. 10. N.D. Volkow, G.-J. Wang, R. Hitzemann, J.S. Fowler, N. Pappas, P. Lowrimore, G. Burr, K. Piscani, J. Overall and A.P. Wolf, Neuropsychopharmacology 12 123-132 (1995).
11. 11. G.F. Koob, A.J. Roberts, G. Schulteis, L.H. Parsons, C.J. Heyser, P. Hyytia, E. Merlo-Pich and F. Weiss, Alcohol Clin Exp Res 22 3-9 (1998).
12. 12. L.L. Devaud, A.L. Morrow, H.E. Criswell, G.R. Breese and G.E. Duncan, Alcohol Clin Exp Res 19 910-914 (1995).
13. 13. G.F. Koob, Ann N Y Acad Sci 877 445-460 (1999).
14. 14. D.T. Stuss and D.F. Benson, The Frontal Lobes. 12-38, Raven Press, New York (1986).
15. 15. N.D. Volkow and J.S. Fowler, Cerebral Cortex (in press).
16. 16. S. Grant, E.D. London, D.B. Newlin, V.L. Villemagne, X. Liu, C. Contoreggi, R.L. Phillips, A.S. Kimes and A. Margolin, Proc Natl Acad Sci U S A 93 12040-12045 (1996).
17. 17. W.J. Schwartz, C.B. Smith, L. Davidsen, H. Savaki, L. Sokoloff, M. Mata, D.J. Fink and H. Gainer, Science 205 723-725 (1979).
18. 18. J.M. Murphy, W.J. McBride, G.J. Gatto, L. Lumeng and T.K. Li, Pharmacol Biochem Behav 29 169-174 (1988).
19. 19. N.D. Volkow, G.-J. Wang, J.S. Fowler, J. Logan, S.J. Gatley, R. Hitzemann, A.D. Chen and N. Pappas Nature 386 830-833, (1997).
20. 20. N.D. Volkow, J.S. Fowler, G.-J. Wang, R. Hitzemann, J. Logan, D. Schlyer, S. Dewey and A.P. Wolf, Synapse 14 169-177, (1993).
21. 21. D. Hommer, P. Andreasen, D. Rio, W. Williams, U. Ruttimann, R. Momenan, A. Zametkin, R. Rawlings and M. Linnoila, J Neurosci 17 2796-2806 (1997).
22. 22. N.D. Volkow, R. Gur, G.-J. Wang, J.S. Fowler, P.J. Moberg, Y.-S. Ding, J. Logan and G. Smith, Am. J. Psychiatry 155 344-349 (1998).
23. 23. N.D. Volkow, R. Hitzemann, A.P. Wolf, J. Logan, J.S. Fowler, D. Christman, S.L. Dewey, D. Schlyer, G. Burr, S. Vitkun, and J. Hirschowitz, Psychiatry Res 35 39-48 (1990).
24. 24. R.L. Novack, J.C. Lamanna and M. Rosenthal, Neuropharmacology 21 1051-1058 (1982).