Identification of the site of inhibition by omeprazole of a α-β fusion protein of the H,K-ATpase using site-directed mutagenesis

Journal of Biological Chemistry

Volumn 273, Issue 22, 1998, Pages 13719-13728

  Lambrecht, Nils ^a   Corbett, Zachary ^a   Bayle, Denis ^a   Karlish, Steve J D ^b   Sachs, George ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BENZYLOXY 2 METHYLIMIDAZO[1,2 A]PYRIDINE 3 ACETONITRILE; ADENOSINE TRIPHOSPHATASE; CYSTEINE; HYBRID PROTEIN; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; OMEPRAZOLE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME LOCALIZATION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; GENETIC VECTORS; H(+)-K(+)-EXCHANGING ATPASE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OMEPRAZOLE; PROTEIN BIOSYNTHESIS; QUATERNARY AMMONIUM COMPOUNDS; RABBITS; RECOMBINANT FUSION PROTEINS; RUBIDIUM; STOMACH;

ANIMALIA; EUKARYOTA;

EID: 0032577575     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.22.13719     Document Type: Article

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