Association between 8-hydroxy-2'-deoxyguanosine levels in DNA of workers highly exposed to asbestos and their clinical data, occupational and non-occupational confounding factors, and cancer

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 468, Issue 2, 2000, Pages 203-212

  Marczynski, B ^a   Kraus, T ^b   Rozynek, P ^a   Raithel, H J ^b   Baur, X ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

8 Hydroxy 2' deoxyguanosine; Asbestos fibers; Cancer; Human white blood cells; Oxidative DNA damage; Reactive oxygen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ASBESTOS; ASBESTOS FIBER; DNA; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ARTICLE; CANCER; CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; FEMALE; GERMANY; HUMAN; HUMAN CELL; LEUKOCYTE; LUNG CANCER; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE; OXIDATION; PATIENT; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; ASBESTOS; ASBESTOS, SERPENTINE; BIOLOGICAL MARKERS; CALCIUM, DIETARY; CONFOUNDING FACTORS (EPIDEMIOLOGY); DEOXYGUANOSINE; DNA ADDUCTS; DNA DAMAGE; DUST; FEMALE; GERMANY; HORMONES; HUMANS; INFECTION; LEUKOCYTES; MAGNESIUM; MALE; MIDDLE AGED; NEOPLASMS; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; ORGAN SPECIFICITY; OXIDATIVE STRESS; PHARMACEUTICAL PREPARATIONS; REACTIVE OXYGEN SPECIES; RISK FACTORS; SMOKING; VITAMINS;

EID: 0034632209     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(00)00054-1     Document Type: Article

References (25)

1. Mossman B.T., Bignon J., Corn M., Seaton A., Gee J.B. Asbestos: scientific developments and implications for public policy. Science. 247:1990;294-301.
2. Rom W.N., Travis W.D., Brody A.R. Cellular and molecular basis of the asbestos-related diseases. Am. Rev. Respir. Dis. 143:1991;408-422.
3. Kamp D.W., Weitzman S.A. The molecular basis of asbestos induced lung injury. Thorax. 54:1999;638-652.
4. Mossman B.T., Churg A. Mechanisms in the pathogenesis of asbestosis and silicosis. Am. J. Respir. Crit. Care Med. 157:1998;1666-1680.
5. Lutz W.K. Dose-response relationship and low dose extrapolation in chemical carcinogenesis. Carcinogenesis. 11:1990;1243-1247.
6. Jaurand M.-C. Mechanisms of fiber-induced genotoxicity. Environ. Health Perspect. 105(Suppl. 5):1997;1073-1084.
7. Ames B.N., Shigenaga M.K., Hagen T.M. Oxidants, antioxidants and the degenerative diseases of aging. Proc. Natl. Acad. Sci. U. S. A. 90:1993;7915-7922.
8. Loft S., Paulsen H.E. Cancer risk and oxidative DNA damage in man. J. Mol. Med. 74:1996;297-312.
9. Marczynski B., Rozynek P., Kraus T., Schlösser St., Raithel H.J., Baur X. Levels of 8-hydroxy-2′-deoxyguanosine in DNA of white blood cells from workers highly exposed to asbestos in Germany. Mutat. Res. 2000;. submitted.
10. T. Kraus, H.J. Raithel, Frühdiagnostik asbeststaubverursachter Erkrankungen, Schriftenreihe des HVBG, 1998.
11. Kraus T., Raithel H.J., Hering K.G. Evaluation and classification of high-resolution computed tomographic findings in patients with pneumoconiosis. Int. Arch. Occup. Environ. Health. 68:1996;249-254.
12. Halliwell B. Can oxidative DNA damage be used as a biomarker of cancer risk in humans? Problems, resolutions and preliminary results from nutritional supplementation studies. Free Radical Res. 29:1998;469-486.
13. Brondeau M.T., Hesbert A., Beausoleil C., Schneider O. To what extent are biomonitoring data available in chemical risk assessment? Hum. Exp. Toxicol. 18:1999;322-326.
14. Takahashi K., Pan H., Kasai H., Hanaoka T., Feng Y., Liu N., Zhang S., Xu Z., Tsuda T., Yamato H., Higashi T., Okubo T. Relationship between asbestos exposure and 8-hydroxydeoxyguanosine levels in leucocytic DNA of workers at a Chinese asbestos-material plant. Int. J. Occup. Environ. Health. 3:1997;111-119.
15. Helbock H.J., Beckman K.B., Shigenaga M.K., Walter P.B., Woodall A.A., Yeo H.C., Ames B.N. DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Proc. Natl. Acad. Sci. U. S. A. 95:1998;288-293.
16. Burdon R.H., Gill V., Rice-Evans C. Oxidative stress and tumour cell proliferation. Free Radical Res. Commun. 11:1990;65-76.
17. Pelin K., Kivipensas P., Linanainmaa K. Effects of asbestos and man-made vitreous fibers on cell division in cultured human mesothelial cells in comparison to rodent cells. Environ. Mol. Mutagen. 25:1995;118-125.
18. Motykiewicz G., Malusecka E., Grzybowska E., Chorazy M., Zhang Y., Perera F.P., Santelle R. Immunochistochemical quantitation of polycyclic aromatic hydrocarbon-DNA adducts in human lymphocytes. Cancer Res. 55:1995;1417-1422.
19. Takeuchi T., Morimoto K. Increased formation of 8-hydroxydeoxyguanosine, an oxidative DNA damage, in lymphoblasts Fanconi's anaemia patients due to possible catalase deficiency. Carcinogenesis. 14:1993;1115-1120.
20. Okamoto K., Toyokuni S., Uchida K., Ogawa O., Takenewa J., Kahehi Y., Kinoshita H., Hattori-Nakakuki Y., Hiai H., Yoshida O. Formation of 8-hydroxy-2′-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma. Int. J. Cancer. 58:1994;825-829.
21. Shimoda R., Nagashima M., Sakamoto M., Yamaguchi N., Hirohashi S., Yokota J., Kasai H. Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis. Cancer Res. 54:1994;3171-3172.
22. Nagashima M., Tsuda H., Takenoshita S., Nagamachi Y., Hirohashi S., Yokota J., Kasai H. 8-hydroxydeoxyguanosine levels in DNA of human breast cancer are not significantly different from those of non-cancerous breast tissues by the HPLC-ECD method. Cancer Lett. 90:1995;157-162.
23. Degan P., Bonassi S., De Caterina M., Korkina L.G., Pinto L., Scopacasa F., Zatterale A., Calzone R., Pagano G. In vivo accumulation of 8-hydroxy-2′-deoxyguanosine in DNA correlates with release of reactive oxygen species in Fanconi's anaemia families. Carcinogenesis. 16:1995;735-741.
24. Olinski R., Zastawny T.H., Foksinski M., Barecki A., Dizdaroglu M. DNA base modifications and antioxidant enzyme activities in human benign prostatic hyperplasia. Free Radical Biol. Med. 18:1995;807-813.
25. Brown R.K., McBurney A., Lunec J., Kelly F.J. Oxidative damage to DNA in patients with cystic fibrosis. Free Radical Biol. Med. 18:1995;801-806.