Clonazepam release from core-shell type nanoparticles of poly(ε-caprolactone)/poly(ethylene glycol)/poly(ε-caprolactone) triblock copolymers

International Journal of Pharmaceutics

Volumn 200, Issue 2, 2000, Pages 231-242

  Ryu, Jae Gon ^a   Jeong, Young Il ^a   Kim, In Sook ^a   Lee, Jong Hoon ^a   Nah, Jae Woon ^b   Kim, Sung Ho ^a  

^a Chosun University   (South Korea)

^b Sunchon National University   (South Korea)

Author keywords

Clonazepam release; Poly( caprolactone); Poly(ethylene glycol)

Indexed keywords

CLONAZEPAM; COPOLYMER; MACROGOL; NANOPARTICLE; POLYCAPROLACTONE;

ARTICLE; DRUG RELEASE; FLUORESCENCE SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

CLONAZEPAM; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; SPECTROMETRY, FLUORESCENCE;

EID: 0034630867     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00392-6     Document Type: Article

References (24)

1. Cerrai P., Tricoli M., Andruzzi F., Paci M., Paci M. Polyether-polyester block copolymer by non-catalysed polymerization of ε-caprolactone with poly(ethylene glycol). Polymer. 30:1989;338-343.
2. Cheon J.B., Jeong Y.I., Cho C.S. Effects of temperature on diblock copolymer micelle composed of poly(γ-benzyl L-glutamate) and poly(N-isopropylacrylamide). Polymer. 40:1999;2041-2050.
3. Cho C.S., Na J.W., Jeong Y.I., Kim S.H., Lee Y.M., Sung Y.K. Micelle formation of the hexablock copolymer consisting of poly(γ-benzyl L-glutamate) as the hydrophobic part and poly(ethylene oxide) as the hydrophilic part. Polymer (Korea). 19:1995;926-931.
4. Couvreur P., Fattal E., Andremont A. Liposomes and nanoparticles in the treatment of intracellular bacterial infections. Pharm. Res. 8:1991;1079-1086.
5. Dunn S.E., Brindley A., Davis S.S., Davies M.C., Illum L. Polystyrene-poly(ethylene glycol) (PS-PEG 2000) particles as model systems for site specific drug delivery. 2. The effect of PEG surface density on the in vitro cell characterization and in vivo biodistribution. Pharm. Res. 11:1994;1016-1022.
6. Gref R., Minamitake Y., Peracchia M.T., Trubetskoy V., Torchilin V., Langer R. Biodegradable long-circulating polymeric nanospheres. Science. 263:1994;1600-1603.
7. Illum L., Hunneyball I.M., Davis S.S. The effect of hydrophilic coatings on the uptake of colloidal particles by the liver and by peritoneal macrophages. Int. J. Pharm. 29:1986;53-65.
8. Jeong Y.I., Cheon J.B., Kim S.H. et al. Clonazepam release from core-shell type nanoparticles in vitro. J. Control. Release. 51:1998;169-178.
9. Jeong Y.I., Nah J.W., Na H.K. et al. Self-assembling nanospheres of hydrophobized pullulans in water. Drug Dev. Ind. Pharm. 25:1999;917-927.
10. Kalyanasundaram K., Thomas J.K. Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies in micellar systems. J. Am. Chem. Soc. 99:1977;2039-2044.
11. Kataoka K., Kwon G.S., Yokoyama M., Okano T., Sakurai Y. Block copolymer micelles as vehicles for drug delivery. J. Control. Release. 24:1993;119-132.
12. Kwon G., Naito M., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Micelles based on AB block copolymers of poly(ethylene oxide) and poly(β-benzyl L-aspartate. Langmuir. 9:1993;945-949.
13. Kwon G.S., Naito M., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Physical entrapment of adriamycin in AB block copolymer micelles. Pharm. Res. 12:1995;192-195.
14. La S.B., Okano T., Kataoka K. Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(β-benzyl L-aspartate) block copolymer micelles. J. Pharm. Sci. 85:1996;85-90.
15. Langer R. Biometerials and biomedical engineering. Chem. Eng. Sci. 50:1995;4109-4121.
16. Lasic D.D. Mixed micelles in drug delivery. Nature. 355:1992;279-280.
17. Lee J.H., Kopecek J., Andrade J.D. Protein-resistant surfaces prepared by PEO-containing block copolymer surfactants. J. Biomed. Mater. Res. 23:1989;351-368.
18. Leroux J.C., Allemann E., Jaeghere F.D., Doelker E., Gurny R. Biodegradable nanoparticles - from sustained release formulations to improved site specific drug delivery. J. Control. Release. 39:1996;339-350.
19. Marctic P.A., Nair M. Microevironment sensing of block copolymer micelles by fluorescence spectroscopy. J. Colloids Interface Sci. 163:1994;517-519.
20. Nah J.W., Jeong Y.I., Cho C.S. Clonazepam release from core-shell type nanoparticles composed of poly(γ-benzyl L-glutamate) as the hydrophobic part and poly(ethylene oxide) as the hydrophilic part. J. Polym. Sci. B: Polym. Phys. 36:1998;415-423.
21. Vemuri S., Rhodes C.T. Preparation and characterization of liposomes as therapeutic delivery systems: a review. Pharm. Acta Helv. 70:1995;95-111.
22. White H.S. Antiepileptic drugs. Gennaro A.R. 19th Ed Remington: The Science and Practice of Pharmacy. 2:1995;1173-1174 Mack Publishing, Easton, PA.
23. Wilhelm M., Zhao C.L., Wang Y. et al. Poly(styrene-ethylene oxide) block copolymer micelle formation in water: a fluorescence probe study. Macromolecules. 24:1991;1033-1040.
24. Yokoyama M., Miyauchi M., Yamada N., Okano T., Sakurai Y., Kataoka K. Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. Cancer Res. 50:1990;1693-1700.