Conditioned taste aversion and drugs of abuse: A reinterpretation

Behavioral Neuroscience

Volumn 111, Issue 1, 1997, Pages 129-136

  Grigson, Patricia Sue ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; DRUG ABUSE; MALE; NONHUMAN; RAT; REINFORCEMENT; REWARD; TASTE AVERSION; ANIMAL; AVOIDANCE BEHAVIOR; CONDITIONED REFLEX; DOSE RESPONSE; DRINKING; DRUG EFFECT; INTRAPERITONEAL DRUG ADMINISTRATION; LEARNING; MOTIVATION; SPRAGUE DAWLEY RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TASTE;

COCAINE; LITHIUM CHLORIDE; MORPHINE; STREET DRUG;

ANIMALS; ASSOCIATION LEARNING; AVOIDANCE LEARNING; COCAINE; CONDITIONING, CLASSICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SUBCUTANEOUS; LITHIUM CHLORIDE; MALE; MORPHINE; MOTIVATION; RATS; RATS, SPRAGUE-DAWLEY; STREET DRUGS; TASTE;

EID: 0030612689     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.111.1.129     Document Type: Article

References (58)

1. Bardo, M. T., Miller, J. S, & Neisewander, J. L. (1984). Conditioned place preference with morphine: The effect of extinction training on the reinforcing conditioned response. Pharmacology, Biochemistry and Behavior, 21, 545-549.
2. Bechara, A., Martin, G. M., Pridgar, A., & van der Kooy, D. (1993). The parabrachial nucleus: A brain stem substrate critical for mediating the aversive motivational effects of morphine. Behavioral Neuroscience, 107, 147-160.
3. Berger, B. D. (1972). Conditioning of food aversions by injections of psychoactive drugs. Journal of Comparative and Physiological Psychology, 81, 21-26.
4. Bevins, R. A., Delzer, T. A., & Bardo, M. T. (1996). Second-order conditioning detects unexpressed morphine-induced salt aversion. Animal Learning & Behavior, 24(2), 221-229.
5. Blander, A., Hunt, T., Blair, R., & Amit, Z. (1984). Conditioned place preference: An evaluation of morphine's positive reinforcing properties. Psychopharmacology, 84, 124-127.
6. Capaldi, E. D., & Sheffer, J. D. (1992). Contrast and reinforcement in consumption. Learning and Motivation, 23, 63-79.
7. Cappell, H., & LeBlanc, A. E. (1971). Conditioned aversion to saccharin by single administrations of mescaline and d-amphetamine. Psychopharmacologia (Berlin), 22, 22-356.
8. Cappell, H., & LeBlanc, A. E. (1973). Aversive conditioning by psychoaetive drugs: Effects of morphine, alcohol, and chlordiazepoxide. Psychopharmacology, 29, 239-246.
9. Collier, G., & Novell, K. (1967). Saccharin as a sugar surrogate. Journal of Comparative and Physiological Psychology, 64, 404-408.
10. Di Chiara, G., Acquas, E., Tanda, G., & Cadoni, C. (1993). Drugs of abuse: Biochemical surrogates of specific aspects of natural reward? Biochemical Society Symposium, 59, 65-81.
11. Farber, P. D., Gorman, J. E., & Reid, L. D. (1976). Morphine injections in the taste aversion paradigm. Physiological Psychology, 4, 365-368.
12. Ferrari, C. M., O'Connor, D. A., & Riley, A. (1991). Cocaine-induced taste aversions: Effect of route of administration. Pharmacology, Biochemistry and Behavior, 38, 267-271.
13. Flaherty, C. F., & Checke, S. (1982). Anticipation of incentive gain. Animal Learning and Behavior, 10, 177-182.
14. Flaherty, C. F., & Grigson, P. S. (1988). From contrast to reinforcement: Role of response contingency in anticipatory contrast. Journal of Experimental Psychology: Animal Behavior Processes, 14, 165-176.
15. Flaherty, C. F. Grigson, P. S., Checke, S., & Hnat, K. C. (1991). Deprivation state and temporal horizons in anticipatory contrast. Journal of Experimental Psychology: Animal Behavior Processes, 17, 503-518.
16. Flaherty, C. F., Grigson, P. S., Coppotelli, C., & Mitchell, C. (1996). Anticipatory contrast as a function of access time and spatial location. Animal Learning & Behavior, 24, 68-81.
17. Flaherty, C. F., & Rowan, G. A. (1985). Anticipatory contrast: Within-subjects analysis. Animal Learning and Behavior, 13, 2-5.
18. Flaherty, C. F., Turovsky, J., & Krauss, K. L. (1994). Relative hedonic value modulates anticipatory contrast. Physiology & Behavior, 55, 1047-1054.
19. Gaiardi, M., Bartoletti, M., Bacchi, A., Gubellini, C., Costa, M., & Babbini, M. (1991). Role of repeated exposure to morphine in determining its affective properties: Place and taste conditioning studies in rats. Psychopharmacology, 103, 183-186.
20. Gamzu, E. (1977). The multifaceted nature of taste-aversion inducing agents: Is there a single common factor? In L. Barker, M. Best, & M. Domjan (Eds.), Learning mechanisms in food selection. Waco, TX: Baylor University Press.
21. Garcia, J., Ervin, F. R., & Koelling, R. A. (1966). Learning with prolonged delay of reinforcement. Psychonomic Science, 5, 121-122.
22. Garcia, J., Lasiter, P. S., Bermudez-Rattoni, F., & Deems, D. A. (1985). A general theory of aversion learning. In N. S. Braveman & P. Bronstein (Eds.), Annals of The New York Academy of Sciences, 443, 8-21.
23. Gilbert, R. M., & Sherman, I. P. (1970). Palatability-induced polydipsia: Saccharin, sucrose, and water intake in rats, with and without food deprivation. Psychological Reports, 27, 319-325.
24. Grigson, P. S., & Norgren, R. (1995). [Fluid deprived rats prefer saccharine to salt in a two-bottle preference test]. Unpublished raw data.
25. Grill, H. J., & Norgren, R. (1978). The taste reactivity test: I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Research, 143, 263-279.
26. Hunt, T., & Amit, Z. (1987). Conditioned taste aversion induced by self-administered drugs: Paradox revisited. Neuroscience and Biobehavioral Reviews, 1, 107-130.
27. Hunt, T., Spivak, K., & Amit, Z. (1985). Further evaluation of morphine aversion: Maintenance of a taste aversion using a low, nonaversive morphine dose. Behavioral and Neural Biology, 44, 74-79.
28. Kalat, J. W. (1974). Taste salience depends on novelty, not concentration, in taste-aversion learning in the rat. Journal of Comparative and Physiological Psychology, 86, 47-50.
29. Kalat, J. W., & Rozin, P. (1970). "Salience": A factor which can override temporal contiguity in taste-aversion learning. Journal of Comparative and Physiological Psychology, 71, 192-197.
30. Katz, R. J., & Gormazano, G. (1979). A rapid and inexpensive technique for assessing the reinforcing effects of opiate drugs. Pharmacology, Biochemistry and Behavior, 11, 231-233.
31. Koob, G. F. (1992). Drugs of abuse: Anatomy, pharmacology and function of reward pathways. Trends in Pharmacological Science, 13, 177-184.
32. LeBlanc, A. E., & Cappell, H. (1975). Antagonism of morphine-induced aversive conditioning by naloxone. Pharmacology, Biochemistry, and Behavior, 3, 185-188.
33. Lester, D., Nachman, M., & LeMagnen, J. (1970). Aversive conditioning by ethanol in the rat. Quarterly Journal of the Study of Alcohol, 31, 578-586.
34. Lett, B. T., & Grant, V. L. (1989). Conditioned taste preference produced by pairing a taste with a low dose of morphine or sufentanil. Psychopharmacology, 98, 236-239.
35. Lin, H. Q., McGregor, I. S., Atrens, D. M., Christie, M. J., & Jackson, D. M. (1994). Contrasting effects of dopaminergic blockade on MDMA and d-amphetamine conditioned taste aversions. Pharmacology, Biochemistry, and Behavior, 47, 369-374.
36. Lucas, G. A., Timberlake, W., Gawley, D. J., & Drew, J. (1990). Anticipation of future food: Suppression and facilitation of saccharin intake depending on the delay and type of future food. Journal of Experimental Psychology: Animal Behavior Processes, 16, 169-177.
37. Mucha, R. F., & Herz, A. (1985). Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning. Psychopharmacology, 86, 274-280.
38. Mucha, R. F., & Herz, A. (1986). Preference conditioning produced by opioid active and inactive isomers of levorphanol and morphine in rat. Life Science, 38, 241-249.
39. Nachman, M. (1963). Learned aversion to the taste of lithium chloride and generalization to other salts. Journal of Comparative and Physiological Psychology, 56, 343-349.
40. Nachman, M., & Ashe, J. H. (1973). Learned taste aversions in rats as a function of dosage, concentration, and route of administration of LiCl. Physiology and Behavior, 10, 73-78.
41. Parker, L. A. (1984). Behavioral conditioned responses across multiple conditioning/testing trials elicited by lithium- and amphetamine-paired flavors. Behavioral and Neural Biology, 41, 190-199.
42. Parker, L. A. (1988). Positively reinforcing drugs may produce a different kind of CTA than drugs which are not positively reinforcing. Learning and Motivation, 19, 207-220.
43. Parker, L. A. (1991). Taste reactivity responses elicited by reinforcing drugs: A dose-response analysis. Behavioral Neuroscience, 105, 955-964.
44. Parker, L. A. (1993). Taste reactivity responses elicited by cocaine-, phencyclidine-, and methamphetamine-paired sucrose solutions. Behavioral Neuroscience, 107, 118-129.
45. Parker, L. A. (1995). Rewarding drugs produce taste avoidance, but not taste aversion. Neuroscience and Biobehavioral Reviews, 19, 143-151.
46. Parker, L. A. & Carvell, T. (1986). Orofacial and somatic responses elicited by lithium-, nicotine- and amphetamine-paired sucrose solution. Pharmacology, Biochemistry and Behavior, 24, 883-887.
47. Reicher, M. A., & Holman, E. W. (1977). Location preference and flavor aversion reinforced by amphetamine in rats. Animal Learning and Behavior, 5, 343-346.
48. Reilly, S., Grigson, P. S., & Norgren, R. (1993). Parabrachial nucleus lesions and conditioned taste aversion: Evidence supporting an associative deficit. Behavioral Neuroscience, 107, 1005-1017.
49. Revusky, S., & Garcia, J. (1970). Learned associations over long delays. Psychology of Learning and Motivation, 4, 1-84.
50. Revusky, S., Reilly, S. (1989). Attenuation of conditioned taste aversions by external stressors. Pharmacology, Biochemistry and Behavior, 33, 219-226.
51. Riley, A. L., Jacobs, W. J., & LoLordo, V. M. (1978). Morphine-induced taste aversions: A consideration of parameters. Physiological Psychology, 6, 96-100.
52. Siegel, S., Parker, L. A., & Moroz, I. (1995). Morphine-induced taste avoidance is attenuated with multiple conditioning trials. Pharmacology, Biochemistry and Behavior, 50, 299-303.
53. Sklar, L. S., & Amit, Z. (1977). Manipulations of catecholamine systems block the conditioned taste aversion induced by self-administered drugs. Neuropharmacology, 16, 649-655.
54. van Haaren, F., & Hughes, C. (1990). Cocaine-induced conditioned taste aversions in male and female Wistar rats. Pharmacology, Biochemistry and Behavior, 37, 693-696.
55. van Ree, J. M. (1979). Reinforcing stimulus properties of drugs. Neuropharmacology, 18, 963-969.
56. Vogel, J. R., & Nathan, B. A. (1975). Learned taste aversions induced by hypnotic drugs. Pharmacology, Biochemistry and Behavior, 3, 189-194.
57. White, N., Sklar, L., & Amit, Z. (1977). The reinforcing action of morphine and its paradoxical side effect. Psychopharmacology, 52, 63-66.
58. Wise, R. A., Yokel, R. A., & DeWit, H. (1976. March 26). Both positive reinforcement and conditioned aversion from amphetamine and from apomorphine in rats. Science, 191, 1273-1274.