Inability to induce hypertension in normotensive rat expressing AT1 receptor antisense

Circulation Research

Volumn 86, Issue 11, 2000, Pages 1167-1172

  Pachori, Alok S ^b   Wang, Hongwei ^b   Gelband, Craig H ^b   Ferrario, Carlos M ^a   Katovich, Michael J ^b   Raizada, Mohan K ^b  

^a WAKE FOREST UNIVERSITY   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Angiotensin II; Angiotensin type 1 receptor; Gene therapy; Hypertension; Renin angiotensin system

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANTISENSE OLIGONUCLEOTIDE; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE TARGETING; GENE THERAPY; GENETIC TRANSDUCTION; HEART HYPERTROPHY; HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RETROVIRUS; THIRST;

EID: 0034625720     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.11.1167     Document Type: Article

References (28)

1. MacGregor GA. Blood pressure, angiotensin-converting enzyme inhibitors and the kidney. Am J Med. 1992;92:205-275.
2. Kang PM, Landau AJ, Eberhardt, RJ, Frishman WH. Angiotensin II receptor antagonists: a new approach to blockade of the renin-angiotensin system. Am Heart J. 1994;127:1388-1401.
3. van Zwieten PA. Development and trends in the drug treatment of essential hypertension. J Hypertens. 1992;10:S1-S12.
4. Martens JR, Reaves PY, Lu D, Katovich MJ, Berecek KH, Bishop SP, Raizada MK, Gelband CH. Prevention of renovascular and cardiac pathophysiological changes in hypertension by angiotensin II type 1 receptor antisense gene therapy. Proc Natl Acad Sci U S A. 1998;95:2664-2669.
5. Lu D, Raizada MK, Iyer S, Reaves P, Yang H, Katovich MJ. Losartan versus gene therapy: chronic control of high blood pressure in spontaneously hypertensive rats. Hypertension. 1997;30:363-370.
6. Iver SN, Lu D, Katovich MJ, Raizada MK. Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type I receptor antisense. Proc Natl Acad Sci U S A. 1996;93:9960-9965.
7. Gelband CH, Reaves PY, Evans J, Wang H, Katovich MJ, Raizada MK. Angiotensin II type 1 receptor antisense gene therapy prevents altered renal vascular calcium homeostasis in hypertension. Hypertension. 1999; 33:360-365.
8. Wang H, Katovich MJ, Gelband CH, Reaves PY, Phillips MI, Raizada MK. Sustained inhibition of angiotensin I-converting enzyme (ACE) expression and long-term antihypertensive action by virally mediated delivery of ACE antisense cDNA. Circ Res. 1999:85;614-622.
9. 2Rs and angiotinsin II action in astroglial and neuronal cells in primary cultures from the brain. Proc Natl Acad Sci U S A. 1995;92:2918.
10. Mercuro G, Zoncu S, Piano D, Pilia I, Lao A, Melis GB, Cherchi A. Estradiol-17β reduces blood pressure and restores normal amplitude of circadian blood pressure rhythm in postmenopausal hypertension. Am J Hypertens. 1998;11:909-913.
11. Mercuro G, Zoncu S, Pilia I, Lao A, Melis GB, Cherchi A. Effects of acute administration of transdermal estrogen on postmenopausal women with systemic hypertension. Am J Cardiol. 1997;80:652-655.
12. Cagnacci A, Rovati L, Zanni A, Malmussi S, Facchinetti F, Volpe A. Physiological doses of estradiol decrease nocturnal blood pressure in normotensive postmenopausal women. Am J Physiol. 1999;276: H1355-H1360.
13. Kisley LR, Sakai RR, Ma LY, Fluharty SJ. Ovarian steroid regulation of angiotensin II-induced water intake in the rat. Am J Physiol. 1999;276: R90-R96.
14. Ghazi N, Grove KL, Wright JW, Phillips MI, Speth RC. Variations in angiotensin-II release from the rat brain during the estrous cycle. Endocrinology. 1994;135:1945-1950.
15. Seltzer A, Pinto JE, Viglione PN, Correa FM, Libertun C, Tsutsumi K, Steele MK, Saavedra JM. Estrogens regulate angiotensin-converting enzyme and angiotensin receptors in female rat anterior pituitary. Neuroendocrinology. 1992;55:460-467.
16. Katovich MJ, Gelband CH, Reaves P, Wang HW, Raizada MK. Reversal of hypertension by angiotensin II type 1 receptor antisense gene therapy in the adult SHR. Am J Physiol. 1999;277:H1260-H1264.
17. Schelling P, Fischer H, Ganten D. Angiotensin and cell growth: a link to cardiovascular hypertrophy? J Hypertens. 1991;9:3-15.
18. Kim S, Ohta K, Hamaguchi A, Yukimura T, Miura K, Iwao H. Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats Hypertension. 1995;25:1252-1259.
19. Lijnen P, Petrov V. Renin-angiotensin system, hypertrophy and gene expression in cardiac myocytes. J Mol Cell Cardiol. 1999;31:949-970.
20. Pasquie JL, Herizi A, Jover B, Mimran A. Chronic bradykinin infusion and receptor blockade in angiotensin II hypertension in rats. Hypertension. 1999;33:830-834.
21. Brink M, Chrast J, Price SR, Mitch WE, Delafontaine P. Hypertension. 1999;34:1053-1059.
22. 2 angiotensin receptor antagonists in angiotensin II-infused rats. Hypertension. 1998;31: 487-492.
23. Makino N, Sugano M, Hata T, Taguchi S, Yanaga T. Chronic low-dose treatment with enalapril induced cardiac regression of left ventricular hypertrophy. Mol Cell Biochem. 1996;163-164:239-245.
24. Paul M, Stoll M, Kreutz R, Fernandez-Alfonso MS. The cellular basis of angiotensin converting enzyme mRNA expression in rat heart. Basic Res Cardiol. 1996;91(suppl 2):57-63.
25. Abraham G, Simon G. Autopotentiation of pressor responses by subpressor angiotensin II in rats. Am J Hypertens. 1994;7:269-275.
26. Cserep G, Abraham G, Tolins JP, Simon G. Different vascular response to subpressor angiotensin II administration in the mesenteric and renal circulation of rats. Am J Hypertens. 1996;9:385-392.
27. Fink GD, Haywood JR, Bryan WJ, Packwood W, Brody MJ. Central site for pressor action of blood-borne angiotensin in rats. Am J Physiol. 1980;239:R358-R361.
28. Li Q, Dale WE, Hasser EM, Blaine EH. Acute and chronic angiotensin hypertension: neural and nonneural components, time course, and dose dependency. Am J Physiol. 1996;271:R200-R207.