Losartan Versus Gene Therapy: Chronic Control of High Blood Pressure in Spontaneously Hypertensive Rats

Hypertension

Volumn 30, Issue 3, 1997, Pages 363-370

  Lu, Di ^a   Raizada, Mohan K ^a   Iyer, Shridhar ^a   Reaves, Phyllis ^a   Yang, Hong ^a   Katovich, Michael J ^a  

^a Department of Clinical and Health Psychology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II [1 SARCOSINE 8 ISOLEUCINE]; COMPLEMENTARY DNA; IODINE 125; LOSARTAN;

ANIMAL MODEL; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; GENE THERAPY; GENE TRANSFER; HYPERTENSION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RETROVIRUS; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ANTISENSE ELEMENTS (GENETICS); DNA, COMPLEMENTARY; GENE THERAPY; GENE TRANSFER TECHNIQUES; HYPERTENSION; LOSARTAN; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RETROVIRIDAE; TIME FACTORS;

EID: 0030861985     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.30.3.363     Document Type: Article

References (38)

1. Goldfarb DA. Altered vascular reactivity and baroreflex. Ren Vasc Dis Transplant. 1994;21:187-194.
2. Gifford RW. Approach to treatment of hypertension. In: Gifford RW, ed. Hypertension Primer: The Essential High Blood Pressure. Dallas, Tex: American Heart Association; 1993:285-288.
3. Berecek KH, Kirk KA, Nagahama S, Oparil S. Alterations in sympathetic function in spontaneously hypertensive rats after chronic administration of captopril. Am J Physiol. 1987;252:H796-H806.
4. MacGregor GA. Blood pressure, angiotensin-converting enzyme inhibitors and the kidney. Am J Med. 1992;92:205-275.
5. Kang PM, Landau AJ, Eberhardt RT, Frishman WH. Angiotensin II receptor antagonists: a new approach to blockade of the renin-angiotensin system. Am Heart J. 1994;127:1388-1401.
6. Van Zwieten PA. Development and trends in the drug treatment of essential hypertension. J Hypertens. 1992;10:S1-S12.
7. Goldberg MR, Bradstreet TE, McWilliams EJ, Tanaka WK, Lipert S, Bjornsson TD, Waldman SA, Osborne B, Pivadori L, Lewis G. Biochemical effects of losartan, a nonpeptide angiotensin II receptor antagonist, on the renin-angiotensin-aldosterone system in hypertensive patients. Hypertension. 1995;25:37-46.
8. Berecek KH, Zhang L. Biochemistry and cell biology of angiotensin-converting enzyme and converting enzyme inhibitors. In: Mukhopadhyay AK, Raizada MK, eds. Tissue Renin-Angiotensin Systems. New York, NY: Plenum Press; 1995:141-168.
9. Harrap SB, Van der Merwe WM, Griffin SA, Macpherson F, Lever AF. Brief angiotensin-converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long term. Hypertension. 1990;16:603-614.
10. Wu J-N, Berecek KH. Prevention of genetic hypertension by early treatment of spontaneously hypertensive rats with the angiotensin-converting enzyme inhibitor captopril. Hypertension. 1993;22:139-146.
11. Berecek KH, King SJ, Wu J-N. Angiotensin-converting enzyme and converting enzyme inhibitors. In: Raizada MK, Phillips MI, Sumners C, eds. Cellular and Molecular Biology of the Renin-Angiotensin System. Boca Raton, Fla: CRC Press; 1993:183-220.
12. Burnier M, Waeber B, Brunner HR. The advantages of angiotensin II antagonism. J Hypertens Suppl. 1994;12:S7-S15.
13. Bonnardeaux A, Davies E, Jeunemaitre X, Fery I, Charru A, Clauser E, Tiret L, Combien F, Corvol P, Soubrier F. Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. Hypertension. 1994;24:63-69.
14. Carr AA, Prisant LM. Losartan: first of a new class of angiotensin antagonists for the management of hypertension. J Clin Pharmacol. 1996;36:3-12.
15. Timmermans PBMWM, Wong PC, Chiu AT, Herblin WF, Benfield P, Carini DJ, Lee RJ, Wexler RR, Saye JAM, Smith RD. Angio-tensin II receptor and angiotensin II receptor antagonist. Pharmacol Rev. 1993;45:205-251.
16. 1) receptor gene. Eur Heart J. 1994;15(suppl D):108-112.
17. 1 Rs and angiotensin II action in astroglial and neuronal cells in primary cultures from the brain. Proc Natl Acad Sci U S A. 1995;92:1162-1166.
18. Lu D, Raizada MK. Delivery of angiotensin II type 1 receptor antisense inhibits angiotensin action in neurons from hypertensive rat brain. Proc Natl Acad Sci U S A. 1995;92:2914-2918.
19. Wielbo D, Sernia C, Gyurko R, Phillips MI. Antisense inhibition of hypertension in the spontaneously hypertensive rat. Hypertension. 1995;25:314-319.
20. 1 receptor mRNA and angiotensinogen mRNA in the brains of spontaneously hypertensive rats reduces hypertension of neurogenic origin. Regul Pept. 1993;49:167-174.
21. Phillips MK, Wielbo D, Gyurko R. Antisense inhibition of hypertension: a new strategy for renin-angiotensin candidate genes. Kidney Int. 1994;46:1554-1556.
22. Wielbo D, Simm A, Phillips MI, Toffolo S. Inhibition of hypertension by peripheral administration of antisense oligodeoxynucleotides. Hypertension. 1996;28:147-151.
23. Tomita N, Morishita R, Higaki J, Kaneda Y, Mikami H, Ogihara T. Transient decrease in high blood pressure by in vivo transfer of antisense oligonucleotide agonist rat angiotensinogen. Hypertension. 1995;26:131-136.
24. Lu D, Yu K, Paddy MR, Rowland NE, Raizada MK. Regulation of norepinephrine transporter system by angiotensin II in neuronal cultures of normotensive and spontaneously hypertensive rat brains. Endocrinology. 1996;137:763-772.
25. Iyer SN, Katovich MJ. Effect of chronic losartan potassium treatment on fructose-induced hypertension. Life Sci. 1994;55:139-144.
26. Iyer SN, Wright BE, Strubbes G, Hanley K, Katovich MJ. Chronic losartan treatment blocks isoproterenol-induced dipsogenesis. Physiol Behav. 1995;58:283-286.
27. Iyer SN, Katovich MJ. Vascular reactivity to phenylephrine and angiotensin II in hypertensive rats associated with insulin resistance. Clin Exp Hypertens. 1996;18:227-242.
28. Song K, Kurobe Y, Kanehara H, Okunishi H, Wada T, Inada Y, Nishikawa K, Miyazaki M. Quantitative localization of angiotensin II receptor subtypes in spontaneously hypertensive rats. Blood Press. 1994;5(suppl):21-26.
29. Baker KM, Campanile CP, Trachte GJ, Peach MJ. Identification and characterization of rabbit angiotensin II myocardial receptor. Circ Res. 1994;54:286-293.
30. Raizada MK, Lu D, Tang W, Kurian P, Sumners C. Increased angiotensin II type 1 receptor gene expression in neuronal cultures from spontaneously hypertensive rats. Endocrinology. 1993;132:1715-1722.
31. 1 -adrenergic and angiotensin type 1 receptors in neurons of spontaneously hypertensive rat brain. Hypertension. 1996;27:1277-1283.
32. Balla T, Baukal AJ, Eng S, Catt KJ. Angiotensin II receptor subtypes and biological responses in the adrenal cortex and medulla. Mol Pharmacol. 1991;40:401-406.
33. Bachmann J, Wagner J, Haufe C, Wystrychowski A, Ciechanowiez A, Ganten D. Modulation of blood pressure and the renin-angiotensin system in transgenic and spontaneously hypertensive rats after ovariectomy. J Hypertens Suppl. 1993;11:S226-S227.
34. Kawano Y, Yoshida K, Matsuoka H, Omae T. Chronic effects of central and systemic administration of losartan on blood pressure and baroreceptor reflex in spontaneously hypertensive rats. Am J Hypertens. 1994;7:536-542.
35. 1 receptor attenuates development of high blood pressure in the spontaneously hypertensive rat. In: Program and abstracts of the 10th International Congress of Endocrinology; 1996:105; San Francisco, Calif. Abstract OR32-1.
36. Mukoyama M, Nakajima M, Horiuchi M, Sasamura H, Pratt RE, Dzau VJ. Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. J Biol Chem. 1993;268:24539-24542.
37. Timmermans PBMWM, Benfield P, Chiu AT, Herblin WF, Wong PC, Smith RD. Angiotensin II receptors and functional correlate. Am J Hypertens. 1992;5:2215-2355.
38. Phillips MI. Functions of angiotensin in the central nervous system. Annu Rev Physiol. 1987;49:413-435.