Nitrogen - Carbon-linked (azolylphenyl) oxazolidinones with potent antibacterial activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis [1]

Journal of Medicinal Chemistry

Volumn 41, Issue 26, 1998, Pages 5144-5147

  Genin, Michael J ^a   Hutchinson, Douglas K ^a   Allwine, Debra A ^a   Hester, Jackson B ^a   Emmert, D Edward ^a   Garmon, Stuart A ^a   Ford, Charles W ^a   Zurenko, Gary E ^a   Hamel, Judith C ^a   Schaadt, Ronda D ^a   Stapert, Douglas ^a   Yagi, Betty H ^a   Friis, Janice M ^a   Shobe, Eric M ^a   Adams, Wade J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; EPEREZOLID; LINEZOLID; NITROGEN; OXAZOLIDINONE DERIVATIVE; PNU 171933; PNU 172576; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; HAEMOPHILUS INFLUENZAE; LETTER; MORAXELLA CATARRHALIS; MORTALITY; MULTIDRUG RESISTANCE; PENICILLIN RESISTANCE; PROTEIN SYNTHESIS; TRANSLATION INITIATION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; COLONY COUNT, MICROBIAL; HAEMOPHILUS INFLUENZAE; INHIBITORY CONCENTRATION 50; INJECTIONS, INTRAVENOUS; MALE; MICE; MORAXELLA (BRANHAMELLA) CATARRHALIS; OXAZOLES; PYRAZOLES; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; STAPHYLOCOCCAL INFECTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032542257     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980546k     Document Type: Letter

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