The antinociceptive effect induced by FR140423 is mediated through spinal 5-HT(2A) and 5-HT3 receptors

European Journal of Pharmacology

Volumn 409, Issue 2, 2000, Pages 167-172

  Ochi, Takehiro ^a   Goto, Toshio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

5 HT(2A) receptor; 5 HT3 receptor; Antinociception; FR140423; Mice; Serotonergic system; Spinal cord

Indexed keywords

1 (1 METHYL 5 INDOLYL) 3 (3 METHYL 5 ISOTHIAZOLYL)UREA; 1 (2 METHOXYPHENYL)PIPERAZINE; 2 METHYLSEROTONIN; 3 (DIFLUOROMETHYL) 1 (4 METHOXYPHENYL) 5 [4 (METHYLSULFINYL)PHENYL]PYRAZOLE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; 6 CHLORO 5 METHYL N [6 (2 METHYLPYRIDIN 3 YLOXY)PYRIDIN 3 YL]INDOLINE 1 CARBOXAMIDE; ALPHA METHYLSEROTONIN; BEMESETRON; KETANSERIN; METHYSERGIDE; MORPHINE; N (1 METHYL 5 INDOLYL) N' (3 METHYLISOTHIAZOL 5 YL)UREA; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2B ANTAGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; MALE; MECHANICAL STIMULATION; MOUSE; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; SPINAL CORD; TAIL PINCH TEST;

ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; KETANSERIN; MALE; METHYSERGIDE; MICE; PAIN; PAIN MEASUREMENT; PIPERAZINES; PYRAZOLES; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SPINAL CORD; SULFOXIDES; TROPANES;

EID: 0034624261     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00832-3     Document Type: Article

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