Synthesis and biological activity of a novel 11a-homo (cyclohexyl) prostaglandin

Journal of Medicinal Chemistry

Volumn 43, Issue 18, 2000, Pages 3400-3407

  Klimko, P G ^a   Davis, T L ^a   Griffin, B W ^a   Sharif, N A ^a  

^a ALCON RESEARCH LTD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16 (3 CHLOROPHENOXY) 9,11A,15 TRIHYDROXY 17,18,19,20 TETRANOR 11A HOMO 5,13 PROSTADIENOIC ACID; ALDEHYDE; BROMIDE; CARBONYL DERIVATIVE; CLOPROSTENOL; CYCLOHEXANE; CYCLOPENTANE; HYDROXYL GROUP; KETONE DERIVATIVE; OXIDE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BROMINATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; GLAUCOMA; INTRAOCULAR PRESSURE; ISOMERISM; MOUSE; NONHUMAN; SECOND MESSENGER; STEREOCHEMISTRY;

3T3 CELLS; ANIMALS; CLOPROSTENOL; CORPUS LUTEUM; FEMALE; INOSITOL PHOSPHATES; LIGANDS; MICE; RECEPTORS, PROSTAGLANDIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034618634     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990587w     Document Type: Article

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