Alzheimer's disease: An inflammatory disease?

Neurobiology of Aging

Volumn 21, Issue 3, 2000, Pages 433-436

  Fassbender, Klaus ^a   Masters, Colin ^b   Beyreuther, Konrad ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; CHEMOKINE; CYTOKINE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ALZHEIMER DISEASE; HUMAN; INFLAMMATION; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENILE PLAQUE; SHORT SURVEY;

EID: 0034612057     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(00)00147-0     Document Type: Note

References (24)

1. 2+-accumulation . Proc Natl Acad Sci USA. 92:1995;9328-9332.
2. Masters C.L., Beyreuther K. Alzheimer's disease. BMJ. 316:1998;446-448.
3. Ernst R.L., Hay J.W. The US economic and social costs of Alzheimer's disease revisited. Am J Public Health. 84:1994;1261-1264.
4. Blasko I., Marx F., Steiner E., Hartmann T., Grubeck-Loebenstein B. TNFα plus IFNγ induce the production of Alzheimer-amyloid peptides and decrease the secretion of APPs. FASEB J. 12:1999;63-68.
5. Buxbaum J.D., Oishi M., Chen H.I., Pinkas-Kramarski R., Jaffe E.A., Gandy S.E., Greengard P. Cholinergic agonists and interleukin 1 regulate processing and secretion of Alzheimer β/A4 amyloid protein precursor. Proc Natl Acad Sci USA. 89:1992;10075-10078.
6. Castillo G.M., Ngo C., Cummings J., Wight T.N., Snow A.D. Perlecan binds to the β-amyloid proteins (Aβ) of Alzheimer's disease, accelerates Aβ fibril formation, and maintains Aβ fibril stability. J Neurochem. 69:1997;2452-2465.
7. Eikelenboom P., Stam F.C. Immunoglobulins and complement factors in senile plaques. An immunoperoxydase study. Acta Neuropathol. 57:1982;239-242.
8. El Khoury J., Hickman S.E., Thomas C.A., CAO L., Silverstein S.C., Loike J.D. Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils. Nature. 382:1996;716-719.
9. Games D., Adams D., Alessandrini R., Varbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature. 373:1995;523-527.
10. Griffin S.T., Sheng J.G., Roberts G.W., Mrak R.E. Interleukin-1 (IL-1) expression in different plaque types in Alzheimer's disease significance in plaque evolution . J Neuropathol Exp Neurol. 54:1995;276-281.
11. Hauss-Wegrzyniak B., Willard L.B., Del Soldato P., Pepeu G., Wenk G.L. Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS. Brain Res. 815:1999;36-43.
12. Hirose Y., Imai Y., Nakajima K., Takemoto N., Toya S., Kohsaka S. Glial conditioned medium alters the expression of amyloid precursor protein in SH-SY5Y neuroblastoma cells. Biochem Biophys Res Commun. 198:1994;504-509.
13. Ishii K, Muelhauser F, Liebl U, Picard M, Kühl S, Penke B, Bayer T, Hennerici M, Wiessler M, Beyreuther K, Hartmann T, Fassbender K. Subacute NO generation induced by Alzheimer's β-amyloid in the living brain: reversal by inhibition of the inducible NO synthase. FASEB J 2000, In press.
14. Lieb K., Fiebich B.L., Schaller H., Berger M., Bauer J. IL-1 β and TNF-α induce expression of α-1-antichymotrypsin in human astrocytoma cells by activation of nuclear factor-κ B. J Neurochem. 67:1996;2039-2044.
15. McGeer P.L., Schulzer M., McGeer E.G. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease a review of 17 epidemiologic studies . Neurology. 47:1996;425-432.
16. Meda L., Cassatella M.A., Szendrei G.I., Otvos L. Jr, Baron P., Villalba M., Ferrari D., Rossi F. Activation of microglial cells by β-amyloid protein and interferon-γ Nature. 374:1995;647-650.
17. Mentlein R., Ludwig R., Martensen I. Proteolytic degradation of Alzheimer's disease amyloid β-peptide by a metalloproteinase from microglia cells. J Neurochem. 70:1998;721-726.
18. Rogers J., Luber-Narod J., Styren S.D., Civin W.H. Expression of immune system-associated antigens by cells of the human central nervous system relationship to the pathology of Alzheimer's disease . Neurobiol Aging. 9:1988;339-349.
19. Rogers J., Kirby L.C., Hempelman S.R., Berry D.L., McGeer P.L., Kaszniak A.W., Zalinski J., Cofield M., Mansukhani L., Willson P. Clinical trial of indomethacin in Alzheimer's disease. Neurology. 43:1993;1609-1611.
20. Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Liao Z., Lieberburg I., Motter R., Mutter L., Soriano F., Shopp G., Vasquez N., Vandervert C., Walker S., Wogulis M., Yednock T., Games D., Seubert P. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 400:1999;173-177.
21. Weldon D.T., Rogers S.D., Ghilardi J.R., Finke M.P., Cleary J.P., O'Hare E., Esler W.P., Maggio J.E., Mantyh P.W. Fibrillar β-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo. J Neurosci. 18:1998;2161-2173.
22. Wyss-Coray T., Lin C., Sanan D.A., Mucke L., Masliah E. Chronic overproduction of TGF-β1 in astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice. Am J Pathol. 156:2000;139-150.
23. Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., Schmidt A.M. RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease. Nature. 382:1996;685-691.
24. Yermakova A., Rollins J., Callahan L.M., Rogers J., O'Banion M.K. Cyclooxygenase-1 in human Alzheimer's and control brain quantitative analysis of expression by microglia and CA3 hippocampal neurons . J Neuropathol Exp Neurol. 58:1999;1135-1146.