Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity

Journal of Medicinal Chemistry

Volumn 43, Issue 20, 2000, Pages 3752-3760

  Van Acker, F A A ^a,b   Hageman, J A ^b   Haenen, G R M M ^c   Van der Vijgh, W J F ^a   Bast, A ^c   Menge, W M P B ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3',4' DIHYDROXYPHENYL)FLAVONE DERIVATIVE; ANTIOXIDANT; DOXORUBICIN; FLAVONE DERIVATIVE; HYDROXYL GROUP; SCAVENGER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOTOXICITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; HEART PROTECTION; MALE; MICROSOME; NONHUMAN; RAT;

ANIMALS; ANTIOXIDANTS; FLAVONOIDS; FREE RADICAL SCAVENGERS; LIPID PEROXIDATION; MALE; MICROSOMES, LIVER; RATS; RATS, WISTAR;

EID: 0034609815     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000951n     Document Type: Article

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