New aromatic inhibitors of EPSP synthase incorporating hydroxymalonates as novel 3-phosphate replacements

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 2, 1997, Pages 323-334

  Shah, Ajit ^a   Font, Jose L ^a,b   Miller, Michael J ^a   Ream, Joel E ^a   Walker, Mark C ^a   Sikorski, James A ^a  

^a MONSANTO COMPANY   (United States)

^b Astra Arcus USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 PHOSPHOSHIKIMATE 1 CARBOXYVINYLTRANSFERASE; ENZYME INHIBITOR; SHIKIMIC ACID DERIVATIVE; SYNTHETASE;

ARTICLE; COMPETITIVE INHIBITION; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE; ALKYL AND ARYL TRANSFERASES; ENZYME INHIBITORS; ESCHERICHIA COLI; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PHOSPHATES; RECOMBINANT PROTEINS; TARTRONATES; TRANSFERASES;

ESCHERICHIA COLI;

EID: 0031081517     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(96)00239-8     Document Type: Article

References (44)

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