Specificity determinants for the pyruvate dehydrogenase component reaction mapped with mutated and prosthetic group modified lipoyl domains

Journal of Biological Chemistry

Volumn 275, Issue 18, 2000, Pages 13645-13653

  Gong, Xiaoming ^a   Peng, Tao ^a   Yakhnin, Alexander ^a   Zolkiewski, Michal ^a   Quinn, Janet ^b   Yeaman, Stephen J ^b   Roche, Thomas E ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROLIPOAMIDE DEHYDROGENASE; PYRUVATE DEHYDROGENASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATALYSIS; CATTLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GENE MAPPING; GENE MUTATION; LIPOLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MODIFICATION; PROTEIN STABILITY;

ANIMALS; BINDING SITES; CATTLE; ESCHERICHIA COLI; HUMANS; MUTATION; PROTEIN CONFORMATION; PYRUVATE DEHYDROGENASE COMPLEX; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ANIMALIA; BOS TAURUS; EUKARYOTA; MAMMALIA;

EID: 0034607846     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.18.13645     Document Type: Article

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