Synthesis of a water-soluble prodrug of entacapone

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 17, 2000, Pages 1967-1969

  Leppänen, Jukka ^a   Huuskonen, Juhani ^a   Savolainen, Jouko ^a   Nevalainen, Tapio ^a   Taipale, Hannu ^a   Vepsäläinen, Jouko ^a,b   Gynther, Jukka ^a,b   Järvinen, Tomi ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Finncovery Ltd   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE INHIBITOR; ENTACAPONE; LEVODOPA;

ANIMAL TISSUE; ARTICLE; DOPAMINE BRAIN LEVEL; DRUG HYDROLYSIS; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; NONHUMAN; PARKINSON DISEASE; RABBIT;

CATECHOL O-METHYLTRANSFERASE; CATECHOLS; ENZYME INHIBITORS; HYDROGEN-ION CONCENTRATION; PRODRUGS; SOLUBILITY;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0034605143     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00384-X     Document Type: Article

References (23)