Synthesis and structure-activity relationships of novel fungal chitin synthase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 13, 2000, Pages 1459-1462

  Masubuchi, Kazunao ^a   Taniguchi, Mikio ^a   Umeda, Isao ^a   Hattori, Kazuo ^a   Suda, Hitomi ^a   Kohchi, Yasunori ^a   Isshiki, Yoshiaki ^a   Sakai, Toshiya ^a   Kohchi, Masami ^a   Shirai, Michio ^a   Okabe, Hisafumi ^a   Sudoh, Masayuki ^a   Yamazaki, Toshikazu ^a   Shimma, Nobuo ^a  

^a NIPPON ROCHE RESEARCH CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CHITIN SYNTHASE; ENZYME INHIBITOR; RO 09 3024; RO 41 0986; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CHEMICAL MODIFICATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; BENZOPHENONES; CANDIDA; CHITIN SYNTHASE; CRYPTOCOCCUS; DRUG DESIGN; ENZYME INHIBITORS; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

CANDIDA; CANDIDA ALBICANS;

EID: 0034601152     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00257-2     Document Type: Article

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