Heterogeneity of 11β-hydroxysteroid dehydrogenase type 1/microsomal carbonyl reductase (11β-HSD/CR) in guinea pig tissues. Purification of the liver form suggests modification in the cosubstrate binding site

Toxicology

Volumn 144, Issue 1-3, 2000, Pages 63-69

  Oppermann, Udo C T ^a,b   Möbus, Eric ^b   Nagel, Gerd ^b   Maser, Edmund ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

11 hydroxysteroid dehydrogenase; Carbonyl reductase; Dye affinity chromatography; Short chain dehydrogenases reductases (SDR)

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CARBONYL REDUCTASE; HYDROXYSTEROID DEHYDROGENASE; ISOENZYME; XENOBIOTIC AGENT;

AFFINITY CHROMATOGRAPHY; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PURIFICATION; GUINEA PIG; IMMUNOBLOTTING; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; ANIMAL; CELL FRACTIONATION; ENZYME SPECIFICITY; ENZYMOLOGY; IN VITRO STUDY; LIVER; METABOLISM; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ANIMALS; BINDING SITES; CHROMATOGRAPHY, AFFINITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GUINEA PIGS; HYDROXYSTEROID DEHYDROGENASES; IMMUNOBLOTTING; ISOENZYMES; LIVER; MICROSOMES, LIVER; MOLECULAR WEIGHT; SUBCELLULAR FRACTIONS; SUBSTRATE SPECIFICITY; XENOBIOTICS;

EID: 0034599178     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(99)00191-2     Document Type: Article

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