Discovery of potent cyclic pseudopeptide human tachykinin NK-2 receptor antagonists

Journal of Medicinal Chemistry

Volumn 43, Issue 22, 2000, Pages 4041-4044

  Giannotti, D ^a   Perrotta, E ^a   Di Bugno, C ^a   Nannicini, R ^a   Harmat, N J S ^a   Giolitti, A ^a   Patacchini, R ^a   Renzetti, A R ^a   Rotondaro, L ^a   Giuliani, S ^a   Altamura, M ^a   Maggi, C A ^a  

^a Menarini Ricerche SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPEPTIDE; MEN 10627; MEN 11558; NEPADUTANT; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR ANTAGONIST; SAREDUTANT; UNCLASSIFIED DRUG;

BINDING AFFINITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; LETTER; RECEPTOR AFFINITY;

ANIMALS; CHO CELLS; CRICETINAE; HUMANS; MODELS, MOLECULAR; MUSCLE, SMOOTH; PEPTIDES, CYCLIC; POINT MUTATION; PULMONARY ARTERY; RABBITS; RADIOLIGAND ASSAY; RECEPTORS, NEUROKININ-2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034597610     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0010217     Document Type: Letter

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