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Volumn 12, Issue 8, 2000, Pages 315-323

Selective susceptibility of transformed T lymphocytes to induction of apoptosis by PSC 833, an inhibitor of P-glycoprotein

Author keywords

Apoptosis; Ceramide; Lymphoma; P glycoprotein; PSC 833; T lymphocytes

Indexed keywords

ANTINEOPLASTIC AGENT; CERAMIDE; CYCLOSERINE; CYCLOSPORIN DERIVATIVE; DIACYLGLYCEROL KINASE; DNA; DNA FRAGMENT; GLYCOPROTEIN P; VALSPODAR;

EID: 0034574938     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: 10.3727/096504001108747765     Document Type: Article
Times cited : (9)

References (40)
  • 1
    • 0028923624 scopus 로고
    • Clinical studies with modulators of multidrug resistance
    • Fisher, G. A.; Sikic, B. I. Clinical studies with modulators of multidrug resistance. Hematol. Oncol. Clin. North Am. 9:363-382; 1995.
    • (1995) Hematol. Oncol. Clin. North Am. , vol.9 , pp. 363-382
    • Fisher, G.A.1    Sikic, B.I.2
  • 3
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer drugs
    • Hickman, J. A. Apoptosis induced by anticancer drugs. Cancer Metastasis Rev. 11:121-139; 1992.
    • (1992) Cancer Metastasis Rev. , vol.11 , pp. 121-139
    • Hickman, J.A.1
  • 4
    • 0028047116 scopus 로고
    • Apoptosis and growth inhibition in sensitive and resistant leukemic cells treated with anticancer drugs
    • Frankfurt, O. S.; Seckinger, D.; Sugarbaker, E. V. Apoptosis and growth inhibition in sensitive and resistant leukemic cells treated with anticancer drugs. Int. J. Oncol. 4:481-489; 1994.
    • (1994) Int. J. Oncol. , vol.4 , pp. 481-489
    • Frankfurt, O.S.1    Seckinger, D.2    Sugarbaker, E.V.3
  • 5
    • 0029032579 scopus 로고
    • Apoptosis in murine tumors treated with chemotherapy agents
    • Meyn, R. E.; Stephens, L. C.; Hunter, N. R.; Milas, L. Apoptosis in murine tumors treated with chemotherapy agents. Anticancer Drugs 6:443-450; 1995.
    • (1995) Anticancer Drugs , vol.6 , pp. 443-450
    • Meyn, R.E.1    Stephens, L.C.2    Hunter, N.R.3    Milas, L.4
  • 6
    • 0028059964 scopus 로고
    • Mechanisms of apoptosis: Integration of genetic, biochemical, and cellular indicators
    • Stewart, B. W. Mechanisms of apoptosis: Integration of genetic, biochemical, and cellular indicators. J. Natl. Cancer Inst. 86: 1286-1296; 1994.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1286-1296
    • Stewart, B.W.1
  • 8
    • 0029549566 scopus 로고
    • Analysis of the interactions of SDZ PSC 833 ([3′-keto Bmt1-Val2]-cyclosporine), a multidrug resistance modulator, with P-glycoprotein
    • Archinal-Mattheis, A.; Rzepka, R. W.; Watanabe, T.; Kokubu, N.; Itoh, Y.; Combates, N. J.; Bair, K. W.; Cohen, D. Analysis of the interactions of SDZ PSC 833 ([3′-keto Bmt1-Val2]-cyclosporine), a multidrug resistance modulator, with P-glycoprotein. Oncol. Res. 7:603-610; 1995.
    • (1995) Oncol. Res. , vol.7 , pp. 603-610
    • Archinal-Mattheis, A.1    Rzepka, R.W.2    Watanabe, T.3    Kokubu, N.4    Itoh, Y.5    Combates, N.J.6    Bair, K.W.7    Cohen, D.8
  • 9
    • 0025935235 scopus 로고
    • Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative
    • Boesch, D.; Muller, K.; Pourtier-Manzanedo, A.; Loor, F. Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative. Exp. Cell Res. 196:26-32; 1991.
    • (1991) Exp. Cell Res. , vol.196 , pp. 26-32
    • Boesch, D.1    Muller, K.2    Pourtier-Manzanedo, A.3    Loor, F.4
  • 10
    • 0029074062 scopus 로고
    • Circumvention of P-glycoprotein-mediated drug resistance in human leukemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833
    • Jiang, X.-R.; Kelsey, S. M.; Wu, Y.-L.; Newland, A. C. Circumvention of P-glycoprotein-mediated drug resistance in human leukemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833. Br. J. Haematol. 90:375-383; 1995.
    • (1995) Br. J. Haematol. , vol.90 , pp. 375-383
    • Jiang, X.-R.1    Kelsey, S.M.2    Wu, Y.-L.3    Newland, A.C.4
  • 11
    • 0030726109 scopus 로고    scopus 로고
    • Effect on cell kill of addition of multidrug resistance modifiers cyclosporin a and PSC 833 to cytotoxic agents in acute myeloid leukemia
    • Grey, M.; Borg, A. G.; Wood, P.; Burgess, R.; Fisher, A.; Yin, J. A. Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukemia. Leuk. Res. 21:867-874; 1997.
    • (1997) Leuk. Res. , vol.21 , pp. 867-874
    • Grey, M.1    Borg, A.G.2    Wood, P.3    Burgess, R.4    Fisher, A.5    Yin, J.A.6
  • 12
    • 0031950027 scopus 로고    scopus 로고
    • Cytotoxic effect of the cyclosporin PSC 833 in multidrug-resistant leukaemia cells with increased expression of P-glycoprotein
    • Lehne, G.; Rugstad, H. E. Cytotoxic effect of the cyclosporin PSC 833 in multidrug-resistant leukaemia cells with increased expression of P-glycoprotein. Br. J. Cancer 78:593-600; 1998.
    • (1998) Br. J. Cancer , vol.78 , pp. 593-600
    • Lehne, G.1    Rugstad, H.E.2
  • 13
    • 0032980591 scopus 로고    scopus 로고
    • Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents
    • Lehne, G.; De Angelis, P.; den Boer, M.; Rugstad, H. E. Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents. Leukemia 13:768-778; 1999.
    • (1999) Leukemia , vol.13 , pp. 768-778
    • Lehne, G.1    De Angelis, P.2    Den Boer, M.3    Rugstad, H.E.4
  • 14
    • 0032541179 scopus 로고    scopus 로고
    • The multidrug resistance modulator SDZ PSC 833 is a potent activator of cellular ceramide formation
    • Cabot, M. C.; Han, T.-Y.; Giuliano, A. E. The multidrug resistance modulator SDZ PSC 833 is a potent activator of cellular ceramide formation. FEBS Lett. 431:185-188; 1998.
    • (1998) FEBS Lett. , vol.431 , pp. 185-188
    • Cabot, M.C.1    Han, T.-Y.2    Giuliano, A.E.3
  • 15
    • 0033557521 scopus 로고    scopus 로고
    • SDZ PSC 833, the cyclosporine a analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells
    • Cabot, M. C.; Giuliano, A. E.; Han, T.-Y.; Liu, Y.-Y. SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells. Cancer Res. 59:880-885; 1999.
    • (1999) Cancer Res. , vol.59 , pp. 880-885
    • Cabot, M.C.1    Giuliano, A.E.2    Han, T.-Y.3    Liu, Y.-Y.4
  • 16
    • 0026465461 scopus 로고
    • Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes
    • Chaudhary, P. M.; Mechetner, E. B.; Roninson, I. B. Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes. Blood 80:2735-2739; 1992.
    • (1992) Blood , vol.80 , pp. 2735-2739
    • Chaudhary, P.M.1    Mechetner, E.B.2    Roninson, I.B.3
  • 18
    • 0029758711 scopus 로고    scopus 로고
    • P-glycoprotein in cells of the human immune system
    • Gupta, S.; Aggarwal, S. P-glycoprotein in cells of the human immune system. Immunologist 4:86-90; 1996.
    • (1996) Immunologist , vol.4 , pp. 86-90
    • Gupta, S.1    Aggarwal, S.2
  • 19
    • 0031442280 scopus 로고    scopus 로고
    • Altered expression and function of P-glycoprotein (170 kDa), encoded by the MDR 1 gene, in T cell subsets from aging humans
    • Aggarwal, S.; Tsuruo, T.; Gupta, S. Altered expression and function of P-glycoprotein (170 kDa), encoded by the MDR 1 gene, in T cell subsets from aging humans. J. Clin. Immunol. 17:448-454; 1997.
    • (1997) J. Clin. Immunol. , vol.17 , pp. 448-454
    • Aggarwal, S.1    Tsuruo, T.2    Gupta, S.3
  • 20
    • 0032845403 scopus 로고    scopus 로고
    • Activation of human peripheral blood T cells does not lead to increased P-glycoprotein expression
    • Mu, X. Y.; Gosland, M. P.; Bartik, M. M.; Schimmelpfennig, J.; Kay, N. E. Activation of human peripheral blood T cells does not lead to increased P-glycoprotein expression. J. Clin. Immunol.. 19:239-246; 1999.
    • (1999) J. Clin. Immunol.. , vol.19 , pp. 239-246
    • Mu, X.Y.1    Gosland, M.P.2    Bartik, M.M.3    Schimmelpfennig, J.4    Kay, N.E.5
  • 21
    • 9544240355 scopus 로고    scopus 로고
    • Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes
    • Drach, J.; Gsur, A.; Hamilton, G.; Zhao, S.; Angerler, J.; Fiegl, M.; Zojer, N.; Raderer, M.; Haberl, I.; Andreeff, M.; Huber, H. Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes. Blood 88:1747-1754; 1996.
    • (1996) Blood 88 , pp. 1747-1754
    • Drach, J.1    Gsur, A.2    Hamilton, G.3    Zhao, S.4    Angerler, J.5    Fiegl, M.6    Zojer, N.7    Raderer, M.8    Haberl, I.9    Andreeff, M.10    Huber, H.11
  • 22
    • 0025753363 scopus 로고
    • Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations
    • Flescher, E.; Fossum, D.; Gray, P. J.; Fernandes, G.; Harper, M. J. K.; Talal, N. Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations. J. Immunol. 146: 2553-2559; 1991.
    • (1991) J. Immunol. , vol.146 , pp. 2553-2559
    • Flescher, E.1    Fossum, D.2    Gray, P.J.3    Fernandes, G.4    Harper, M.J.K.5    Talal, N.6
  • 24
    • 0028223777 scopus 로고
    • A rapid and sensitive assay for the detection of DNA fragmentation during early phases of apoptosis
    • Basnakian, A. G.; James, S. J. A rapid and sensitive assay for the detection of DNA fragmentation during early phases of apoptosis. Nucleic Acids Res. 22:2714-2715; 1994.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2714-2715
    • Basnakian, A.G.1    James, S.J.2
  • 25
    • 0025726216 scopus 로고
    • Rapid and simple method measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I.; Migliorati, G.; Pagliacci, M.C.; Grignani, F.; Riccardi, C. A. Rapid and simple method measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139:271-279; 1991.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.A.5
  • 26
    • 0025168334 scopus 로고
    • Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells
    • Dressler, K. A.; Kolesnick, R. N. Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. J. Biol. Chem. 265:14917-14921; 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 14917-14921
    • Dressler, K.A.1    Kolesnick, R.N.2
  • 27
    • 0034651777 scopus 로고    scopus 로고
    • Contrasting effects of aspirin on prostate cancer cells: Suppression of proliferation and induction of drug resistance
    • Rotem, R.; Tzivony, Y.; Flescher, E. Contrasting effects of aspirin on prostate cancer cells: Suppression of proliferation and induction of drug resistance. Prostate 42:172-180; 2000.
    • (2000) Prostate , vol.42 , pp. 172-180
    • Rotem, R.1    Tzivony, Y.2    Flescher, E.3
  • 28
    • 0029025580 scopus 로고
    • Inhibition of cell-mediated cytolysis and P-glycoprotein function in natural killer cells by verapamil isomers and cyclosporine a analogs
    • Klimecki, W. T.; Taylor, C. W.; Dalton, W. S. Inhibition of cell-mediated cytolysis and P-glycoprotein function in natural killer cells by verapamil isomers and cyclosporine A analogs. J. Clin. Immunol. 15:152-158; 1995.
    • (1995) J. Clin. Immunol. , vol.15 , pp. 152-158
    • Klimecki, W.T.1    Taylor, C.W.2    Dalton, W.S.3
  • 31
    • 0026442430 scopus 로고
    • Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: A role in cytotoxic effector function
    • Gupta, S.; Kim, C. H.; Tsuruo, T.; Gollapudi, S. Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: A role in cytotoxic effector function. J. Clin. Immunol. 12:451-458; 1992.
    • (1992) J. Clin. Immunol. , vol.12 , pp. 451-458
    • Gupta, S.1    Kim, C.H.2    Tsuruo, T.3    Gollapudi, S.4
  • 33
    • 0027315279 scopus 로고
    • Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
    • Wesselborg, S.; Janssen, O.; Kabelitz, D. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J. Immunol. 50:4338-4345; 1993.
    • (1993) J. Immunol. , vol.50 , pp. 4338-4345
    • Wesselborg, S.1    Janssen, O.2    Kabelitz, D.3
  • 34
    • 0032782950 scopus 로고    scopus 로고
    • Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid
    • Spinedi, A.; Di Bartolomeo, S.; Di Sano, F.; Rodolfo, C.; Ambrosino, A.; Piacentini, M. Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid. Cell Death Differ. 6:618-623; 1999.
    • (1999) Cell Death Differ. , vol.6 , pp. 618-623
    • Spinedi, A.1    Di Bartolomeo, S.2    Di Sano, F.3    Rodolfo, C.4    Ambrosino, A.5    Piacentini, M.6
  • 36
    • 0031400857 scopus 로고    scopus 로고
    • Calabro, A. Unique synergism or antagonism of combinations of chemotherapeutic and hormonal agents in human prostate cancer cell lines
    • Kreis, W.; Budman, D. R.; Calabro, A. Unique synergism or antagonism of combinations of chemotherapeutic and hormonal agents in human prostate cancer cell lines. Br. J. Urol. 79:196-202; 1997.
    • (1997) Br. J. Urol. , vol.79 , pp. 196-202
    • Kreis, W.1    Budman, D.R.2
  • 37
    • 0029058055 scopus 로고
    • Apoptosis: Lessons from in vitro systems
    • Earnshaw, W. C. Apoptosis: Lessons from in vitro systems. Trends Cell Biol. 5:217-220; 1995.
    • (1995) Trends Cell Biol. , vol.5 , pp. 217-220
    • Earnshaw, W.C.1
  • 38
    • 0034477227 scopus 로고    scopus 로고
    • Aspirin enhances multidrug resistance gene 1 expression in human Molt-4 T lymphoma cells
    • Flescher, E.; Rotem, R.; Kwon, P.; Azare, J.; Jaspers, I.; Cohen, D. Aspirin enhances multidrug resistance gene 1 expression in human Molt-4 T lymphoma cells. Anticancer Res. 20:4441-4444; 2000.
    • (2000) Anticancer Res. , vol.20 , pp. 4441-4444
    • Flescher, E.1    Rotem, R.2    Kwon, P.3    Azare, J.4    Jaspers, I.5    Cohen, D.6
  • 39
    • 0031438213 scopus 로고    scopus 로고
    • The MDR1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes
    • Martel, J.; Payet, M. D.; Dupuis, G. The MDR1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes. Leuk. Res. 21:1077-1086; 1997.
    • (1997) Leuk. Res. , vol.21 , pp. 1077-1086
    • Martel, J.1    Payet, M.D.2    Dupuis, G.3


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