-
1
-
-
0028923624
-
Clinical studies with modulators of multidrug resistance
-
Fisher, G. A.; Sikic, B. I. Clinical studies with modulators of multidrug resistance. Hematol. Oncol. Clin. North Am. 9:363-382; 1995.
-
(1995)
Hematol. Oncol. Clin. North Am.
, vol.9
, pp. 363-382
-
-
Fisher, G.A.1
Sikic, B.I.2
-
3
-
-
0026698173
-
Apoptosis induced by anticancer drugs
-
Hickman, J. A. Apoptosis induced by anticancer drugs. Cancer Metastasis Rev. 11:121-139; 1992.
-
(1992)
Cancer Metastasis Rev.
, vol.11
, pp. 121-139
-
-
Hickman, J.A.1
-
4
-
-
0028047116
-
Apoptosis and growth inhibition in sensitive and resistant leukemic cells treated with anticancer drugs
-
Frankfurt, O. S.; Seckinger, D.; Sugarbaker, E. V. Apoptosis and growth inhibition in sensitive and resistant leukemic cells treated with anticancer drugs. Int. J. Oncol. 4:481-489; 1994.
-
(1994)
Int. J. Oncol.
, vol.4
, pp. 481-489
-
-
Frankfurt, O.S.1
Seckinger, D.2
Sugarbaker, E.V.3
-
5
-
-
0029032579
-
Apoptosis in murine tumors treated with chemotherapy agents
-
Meyn, R. E.; Stephens, L. C.; Hunter, N. R.; Milas, L. Apoptosis in murine tumors treated with chemotherapy agents. Anticancer Drugs 6:443-450; 1995.
-
(1995)
Anticancer Drugs
, vol.6
, pp. 443-450
-
-
Meyn, R.E.1
Stephens, L.C.2
Hunter, N.R.3
Milas, L.4
-
6
-
-
0028059964
-
Mechanisms of apoptosis: Integration of genetic, biochemical, and cellular indicators
-
Stewart, B. W. Mechanisms of apoptosis: Integration of genetic, biochemical, and cellular indicators. J. Natl. Cancer Inst. 86: 1286-1296; 1994.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1286-1296
-
-
Stewart, B.W.1
-
8
-
-
0029549566
-
Analysis of the interactions of SDZ PSC 833 ([3′-keto Bmt1-Val2]-cyclosporine), a multidrug resistance modulator, with P-glycoprotein
-
Archinal-Mattheis, A.; Rzepka, R. W.; Watanabe, T.; Kokubu, N.; Itoh, Y.; Combates, N. J.; Bair, K. W.; Cohen, D. Analysis of the interactions of SDZ PSC 833 ([3′-keto Bmt1-Val2]-cyclosporine), a multidrug resistance modulator, with P-glycoprotein. Oncol. Res. 7:603-610; 1995.
-
(1995)
Oncol. Res.
, vol.7
, pp. 603-610
-
-
Archinal-Mattheis, A.1
Rzepka, R.W.2
Watanabe, T.3
Kokubu, N.4
Itoh, Y.5
Combates, N.J.6
Bair, K.W.7
Cohen, D.8
-
9
-
-
0025935235
-
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative
-
Boesch, D.; Muller, K.; Pourtier-Manzanedo, A.; Loor, F. Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative. Exp. Cell Res. 196:26-32; 1991.
-
(1991)
Exp. Cell Res.
, vol.196
, pp. 26-32
-
-
Boesch, D.1
Muller, K.2
Pourtier-Manzanedo, A.3
Loor, F.4
-
10
-
-
0029074062
-
Circumvention of P-glycoprotein-mediated drug resistance in human leukemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833
-
Jiang, X.-R.; Kelsey, S. M.; Wu, Y.-L.; Newland, A. C. Circumvention of P-glycoprotein-mediated drug resistance in human leukemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833. Br. J. Haematol. 90:375-383; 1995.
-
(1995)
Br. J. Haematol.
, vol.90
, pp. 375-383
-
-
Jiang, X.-R.1
Kelsey, S.M.2
Wu, Y.-L.3
Newland, A.C.4
-
11
-
-
0030726109
-
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin a and PSC 833 to cytotoxic agents in acute myeloid leukemia
-
Grey, M.; Borg, A. G.; Wood, P.; Burgess, R.; Fisher, A.; Yin, J. A. Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukemia. Leuk. Res. 21:867-874; 1997.
-
(1997)
Leuk. Res.
, vol.21
, pp. 867-874
-
-
Grey, M.1
Borg, A.G.2
Wood, P.3
Burgess, R.4
Fisher, A.5
Yin, J.A.6
-
12
-
-
0031950027
-
Cytotoxic effect of the cyclosporin PSC 833 in multidrug-resistant leukaemia cells with increased expression of P-glycoprotein
-
Lehne, G.; Rugstad, H. E. Cytotoxic effect of the cyclosporin PSC 833 in multidrug-resistant leukaemia cells with increased expression of P-glycoprotein. Br. J. Cancer 78:593-600; 1998.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 593-600
-
-
Lehne, G.1
Rugstad, H.E.2
-
13
-
-
0032980591
-
Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents
-
Lehne, G.; De Angelis, P.; den Boer, M.; Rugstad, H. E. Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents. Leukemia 13:768-778; 1999.
-
(1999)
Leukemia
, vol.13
, pp. 768-778
-
-
Lehne, G.1
De Angelis, P.2
Den Boer, M.3
Rugstad, H.E.4
-
14
-
-
0032541179
-
The multidrug resistance modulator SDZ PSC 833 is a potent activator of cellular ceramide formation
-
Cabot, M. C.; Han, T.-Y.; Giuliano, A. E. The multidrug resistance modulator SDZ PSC 833 is a potent activator of cellular ceramide formation. FEBS Lett. 431:185-188; 1998.
-
(1998)
FEBS Lett.
, vol.431
, pp. 185-188
-
-
Cabot, M.C.1
Han, T.-Y.2
Giuliano, A.E.3
-
15
-
-
0033557521
-
SDZ PSC 833, the cyclosporine a analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells
-
Cabot, M. C.; Giuliano, A. E.; Han, T.-Y.; Liu, Y.-Y. SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells. Cancer Res. 59:880-885; 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 880-885
-
-
Cabot, M.C.1
Giuliano, A.E.2
Han, T.-Y.3
Liu, Y.-Y.4
-
16
-
-
0026465461
-
Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes
-
Chaudhary, P. M.; Mechetner, E. B.; Roninson, I. B. Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes. Blood 80:2735-2739; 1992.
-
(1992)
Blood
, vol.80
, pp. 2735-2739
-
-
Chaudhary, P.M.1
Mechetner, E.B.2
Roninson, I.B.3
-
17
-
-
0027238385
-
Expression of multidrug resistance gene (MDR-1) in human normal leukocytes
-
Damiani, D.; Michieli, M.; Michelutti, A.; Geromin, A.; Raspadori, D.; Fanin, R.; Savignano, C.; Giacca, M.; Pileri, S.; Malolardi, F.; Baccarani, M. Expression of multidrug resistance gene (MDR-1) in human normal leukocytes. Haematologica 78:12-17; 1993.
-
(1993)
Haematologica
, vol.78
, pp. 12-17
-
-
Damiani, D.1
Michieli, M.2
Michelutti, A.3
Geromin, A.4
Raspadori, D.5
Fanin, R.6
Savignano, C.7
Giacca, M.8
Pileri, S.9
Malolardi, F.10
Baccarani, M.11
-
18
-
-
0029758711
-
P-glycoprotein in cells of the human immune system
-
Gupta, S.; Aggarwal, S. P-glycoprotein in cells of the human immune system. Immunologist 4:86-90; 1996.
-
(1996)
Immunologist
, vol.4
, pp. 86-90
-
-
Gupta, S.1
Aggarwal, S.2
-
19
-
-
0031442280
-
Altered expression and function of P-glycoprotein (170 kDa), encoded by the MDR 1 gene, in T cell subsets from aging humans
-
Aggarwal, S.; Tsuruo, T.; Gupta, S. Altered expression and function of P-glycoprotein (170 kDa), encoded by the MDR 1 gene, in T cell subsets from aging humans. J. Clin. Immunol. 17:448-454; 1997.
-
(1997)
J. Clin. Immunol.
, vol.17
, pp. 448-454
-
-
Aggarwal, S.1
Tsuruo, T.2
Gupta, S.3
-
20
-
-
0032845403
-
Activation of human peripheral blood T cells does not lead to increased P-glycoprotein expression
-
Mu, X. Y.; Gosland, M. P.; Bartik, M. M.; Schimmelpfennig, J.; Kay, N. E. Activation of human peripheral blood T cells does not lead to increased P-glycoprotein expression. J. Clin. Immunol.. 19:239-246; 1999.
-
(1999)
J. Clin. Immunol..
, vol.19
, pp. 239-246
-
-
Mu, X.Y.1
Gosland, M.P.2
Bartik, M.M.3
Schimmelpfennig, J.4
Kay, N.E.5
-
21
-
-
9544240355
-
Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes
-
Drach, J.; Gsur, A.; Hamilton, G.; Zhao, S.; Angerler, J.; Fiegl, M.; Zojer, N.; Raderer, M.; Haberl, I.; Andreeff, M.; Huber, H. Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes. Blood 88:1747-1754; 1996.
-
(1996)
Blood 88
, pp. 1747-1754
-
-
Drach, J.1
Gsur, A.2
Hamilton, G.3
Zhao, S.4
Angerler, J.5
Fiegl, M.6
Zojer, N.7
Raderer, M.8
Haberl, I.9
Andreeff, M.10
Huber, H.11
-
22
-
-
0025753363
-
Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations
-
Flescher, E.; Fossum, D.; Gray, P. J.; Fernandes, G.; Harper, M. J. K.; Talal, N. Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations. J. Immunol. 146: 2553-2559; 1991.
-
(1991)
J. Immunol.
, vol.146
, pp. 2553-2559
-
-
Flescher, E.1
Fossum, D.2
Gray, P.J.3
Fernandes, G.4
Harper, M.J.K.5
Talal, N.6
-
23
-
-
0028893253
-
Induction of transcription factors in human T lymphocytes by aspirin-like drugs
-
Flescher, E.; Ledbetter, J. A.; Ogawa, N.; Vela-Roch, N.; Fossum, D.; Dang, H.; Talal, N. Induction of transcription factors in human T lymphocytes by aspirin-like drugs. Cell. Immunol. 160:232-239; 1995.
-
(1995)
Cell. Immunol.
, vol.160
, pp. 232-239
-
-
Flescher, E.1
Ledbetter, J.A.2
Ogawa, N.3
Vela-Roch, N.4
Fossum, D.5
Dang, H.6
Talal, N.7
-
24
-
-
0028223777
-
A rapid and sensitive assay for the detection of DNA fragmentation during early phases of apoptosis
-
Basnakian, A. G.; James, S. J. A rapid and sensitive assay for the detection of DNA fragmentation during early phases of apoptosis. Nucleic Acids Res. 22:2714-2715; 1994.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 2714-2715
-
-
Basnakian, A.G.1
James, S.J.2
-
25
-
-
0025726216
-
Rapid and simple method measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
Nicoletti, I.; Migliorati, G.; Pagliacci, M.C.; Grignani, F.; Riccardi, C. A. Rapid and simple method measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139:271-279; 1991.
-
(1991)
J. Immunol. Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.A.5
-
26
-
-
0025168334
-
Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells
-
Dressler, K. A.; Kolesnick, R. N. Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. J. Biol. Chem. 265:14917-14921; 1990.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 14917-14921
-
-
Dressler, K.A.1
Kolesnick, R.N.2
-
27
-
-
0034651777
-
Contrasting effects of aspirin on prostate cancer cells: Suppression of proliferation and induction of drug resistance
-
Rotem, R.; Tzivony, Y.; Flescher, E. Contrasting effects of aspirin on prostate cancer cells: Suppression of proliferation and induction of drug resistance. Prostate 42:172-180; 2000.
-
(2000)
Prostate
, vol.42
, pp. 172-180
-
-
Rotem, R.1
Tzivony, Y.2
Flescher, E.3
-
28
-
-
0029025580
-
Inhibition of cell-mediated cytolysis and P-glycoprotein function in natural killer cells by verapamil isomers and cyclosporine a analogs
-
Klimecki, W. T.; Taylor, C. W.; Dalton, W. S. Inhibition of cell-mediated cytolysis and P-glycoprotein function in natural killer cells by verapamil isomers and cyclosporine A analogs. J. Clin. Immunol. 15:152-158; 1995.
-
(1995)
J. Clin. Immunol.
, vol.15
, pp. 152-158
-
-
Klimecki, W.T.1
Taylor, C.W.2
Dalton, W.S.3
-
29
-
-
0028980990
-
Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833
-
Gonzalez, O.; Colombo, T.; De Fusco, M.; Imperatori, L.; Zucchetti, M.; D'Incalci, M. Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833. Cancer Chemother. Pharmacol. 36:335-340; 1995.
-
(1995)
Cancer Chemother. Pharmacol.
, vol.36
, pp. 335-340
-
-
Gonzalez, O.1
Colombo, T.2
De Fusco, M.3
Imperatori, L.4
Zucchetti, M.5
D'Incalci, M.6
-
30
-
-
0032704158
-
Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin
-
Mansat-De Mas, V.; Bezombes, C.; Quillet-Mary, A.; Bettaieb, A.; De Thonel D'orgeix, A.; Laurent, G.; Jaffrezou, J.-P. Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. Mol. Pharmacol. 56:867-874; 1999.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 867-874
-
-
Mansat-De Mas, V.1
Bezombes, C.2
Quillet-Mary, A.3
Bettaieb, A.4
De Thonel D'Orgeix, A.5
Laurent, G.6
Jaffrezou, J.-P.7
-
31
-
-
0026442430
-
Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: A role in cytotoxic effector function
-
Gupta, S.; Kim, C. H.; Tsuruo, T.; Gollapudi, S. Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: A role in cytotoxic effector function. J. Clin. Immunol. 12:451-458; 1992.
-
(1992)
J. Clin. Immunol.
, vol.12
, pp. 451-458
-
-
Gupta, S.1
Kim, C.H.2
Tsuruo, T.3
Gollapudi, S.4
-
32
-
-
0026040157
-
Multidrug resistance activity in human lymphocytes
-
Coon, J. S.; Wang, Y.; Bines, S. D.; Markham, P. N.; Chong, A. S. F.; Gebel, H. M. Multidrug resistance activity in human lymphocytes. Hum. Immunol. 32:134-140; 1991.
-
(1991)
Hum. Immunol.
, vol.32
, pp. 134-140
-
-
Coon, J.S.1
Wang, Y.2
Bines, S.D.3
Markham, P.N.4
Chong, A.S.F.5
Gebel, H.M.6
-
33
-
-
0027315279
-
Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
-
Wesselborg, S.; Janssen, O.; Kabelitz, D. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J. Immunol. 50:4338-4345; 1993.
-
(1993)
J. Immunol.
, vol.50
, pp. 4338-4345
-
-
Wesselborg, S.1
Janssen, O.2
Kabelitz, D.3
-
34
-
-
0032782950
-
Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid
-
Spinedi, A.; Di Bartolomeo, S.; Di Sano, F.; Rodolfo, C.; Ambrosino, A.; Piacentini, M. Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid. Cell Death Differ. 6:618-623; 1999.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 618-623
-
-
Spinedi, A.1
Di Bartolomeo, S.2
Di Sano, F.3
Rodolfo, C.4
Ambrosino, A.5
Piacentini, M.6
-
35
-
-
0033178928
-
Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes
-
Delpy, E.; Hatem, S. N.; Andrieu, N.; de Vaumas, C.; Henaff, M.; Rucker-Martin, C.; Jaffrezou, J.-P.; Laurent, G.; Levade, T.; Mercadier, J.-J. Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes. Cardiovas. Res. 43:398-407; 1999.
-
(1999)
Cardiovas. Res.
, vol.43
, pp. 398-407
-
-
Delpy, E.1
Hatem, S.N.2
Andrieu, N.3
De Vaumas, C.4
Henaff, M.5
Rucker-Martin, C.6
Jaffrezou, J.-P.7
Laurent, G.8
Levade, T.9
Mercadier, J.-J.10
-
36
-
-
0031400857
-
Calabro, A. Unique synergism or antagonism of combinations of chemotherapeutic and hormonal agents in human prostate cancer cell lines
-
Kreis, W.; Budman, D. R.; Calabro, A. Unique synergism or antagonism of combinations of chemotherapeutic and hormonal agents in human prostate cancer cell lines. Br. J. Urol. 79:196-202; 1997.
-
(1997)
Br. J. Urol.
, vol.79
, pp. 196-202
-
-
Kreis, W.1
Budman, D.R.2
-
37
-
-
0029058055
-
Apoptosis: Lessons from in vitro systems
-
Earnshaw, W. C. Apoptosis: Lessons from in vitro systems. Trends Cell Biol. 5:217-220; 1995.
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 217-220
-
-
Earnshaw, W.C.1
-
38
-
-
0034477227
-
Aspirin enhances multidrug resistance gene 1 expression in human Molt-4 T lymphoma cells
-
Flescher, E.; Rotem, R.; Kwon, P.; Azare, J.; Jaspers, I.; Cohen, D. Aspirin enhances multidrug resistance gene 1 expression in human Molt-4 T lymphoma cells. Anticancer Res. 20:4441-4444; 2000.
-
(2000)
Anticancer Res.
, vol.20
, pp. 4441-4444
-
-
Flescher, E.1
Rotem, R.2
Kwon, P.3
Azare, J.4
Jaspers, I.5
Cohen, D.6
-
39
-
-
0031438213
-
The MDR1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes
-
Martel, J.; Payet, M. D.; Dupuis, G. The MDR1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes. Leuk. Res. 21:1077-1086; 1997.
-
(1997)
Leuk. Res.
, vol.21
, pp. 1077-1086
-
-
Martel, J.1
Payet, M.D.2
Dupuis, G.3
-
40
-
-
0030050848
-
Functional expression of Fas and Fas ligand on human gut lamina Propria T lymphocytes
-
De Maria, R.; Boirivant, M.; Cifone, M. G.; Roncaioli, P.; Hahne, M.; Tschopp, J.; Pallone, F.; Santoni, A.; Testi, R. Functional expression of Fas and Fas ligand on human gut lamina Propria T lymphocytes. J. Clin. Invest. 97:316-322; 1996.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 316-322
-
-
De Maria, R.1
Boirivant, M.2
Cifone, M.G.3
Roncaioli, P.4
Hahne, M.5
Tschopp, J.6
Pallone, F.7
Santoni, A.8
Testi, R.9
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