Effects of a fermented milk drink containing lactobacillus casei strain shirota on the immune system in healthy human subjects

Bioscience, Biotechnology and Biochemistry

Volumn 64, Issue 12, 2000, Pages 2706-2708

  Nagao, Fumiko ^a   Nakayama, Masafumi ^a   Muto, Takashi ^a   Okumura, Ko ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Fermented milk; Immune system; Lactobacillus casei strain Shirota; NK cell activity

Indexed keywords

ADULT; ANIMAL; ARTICLE; CASE CONTROL STUDY; CATTLE; DRUG EFFECT; FEMALE; FERMENTATION; HUMAN; IMMUNE SYSTEM; IMMUNOLOGY; LACTOBACILLUS CASEI; MALE; MICROBIOLOGY; MILK; NATURAL KILLER CELL; T LYMPHOCYTE;

ADULT; ANIMALS; CASE-CONTROL STUDIES; CATTLE; FEMALE; FERMENTATION; HUMANS; IMMUNE SYSTEM; KILLER CELLS, NATURAL; LACTOBACILLUS CASEI; MALE; MILK; T-LYMPHOCYTES;

EID: 0034571314     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.64.2706     Document Type: Article

References (23)

1. Gill, H. S., Stimulation of the immune system by lactic cultures.Int. Dairy Journal,8, 535-544 (1998).
2. Salminen, S., Ouwehand, A. C., and Isolauri, E., Clinical applications of probiotic bacteria.Int. Dairy Journal,8, 563-572 (1998).
3. Kato, I., Endo, K., and Yokokura, T., Effects of oral administration ofLactobacillus caseion antitumor responses induced by tumor resection in mice.J. Im-munopharmacol.,16, 29-36 (1994).
4. Takagi, T., Matsuzaki, T., Sato, M., Nomoto, K., Morotomi, M., and Yokokura, T., Inhibitory effect of oral administration ofLactobacillus caseion 3-methylcholanthrene-induced carcinogenesis in mice.Med. Microbiol. Immunol.,188, 111-116 (1999).
5. Matsuzaki, T., Immunomodulation by treatment withLactobacillus caseistrain Shirota.Int. J. Food Microbiol.,41, 133-140 (1998).
6. Aso, Y., Akaza, H., and the BLP Study Group, Prophylactic effect of aLactobacillus caseipreparation on the recurrence of superficial bladder cancer.Urol. Int.,49, 125-129 (1992).
7. Aso, Y., Akaza, H., Kotake, T., Tsukamoto, T., Imai, K., Naito, S., and the BLP Study Group, Preventive effect of aLactobacillus caseipreparation on the recurrence of superficial bladder cancer in a double-blind trial.Eur. Urol.,27, 104-109 (1995).
8. Ohashi, T., Nakai, S., Tsukamoto, T., Akaza, H., Kitamura, T., Kawabe, K., Kotake, T., Naito, S., Saito, Y., Kitagawa, M., Aso, Y., Habitual intake of lactic acid bacteria and risk reduction of bladder cancer.Proceedings of the American Association for Cancer Research,41, 559 (2000).
9. Spanhaak, S., Havenaar, R., and Schaafsma, G., The effect of consumption of milk fermented byLactobacillus caseistrain Shirota on the intestinal microflora and immune parameters in humans.Eur. J. Clin. Nutr.,52, 899-907 (1998).
10. Nagao, F., Yabe, T., Xu, M., and Okumura, K., Phenotypical and functional analyses of natural killer cells from low NK activity individuals among healthy and patient populations.Nat. Immun.,14, 225-233 (1995).
11. Herberman, R. B. and Oltaldo, J. R., Natural killer cells: Their roles in defences against disease.Science,214, 24-30 (1981).
12. Talmadge, J. E., Meyers, K. M., Prieur, D. J., and Starkey, J. R., Role of NK cells in tumor growth and metastasis in beige mice.Nature,248, 622-624 (1980).
13. Bartizal, K. F., Salkowski, C., and Batish, E., The influence of a gastrointestinal microflora on natural killer cell activity.J. Reticuloendothel. Soc.,33, 381-390 (1983).
14. Bartizal, K. F., Salkowski, C., Pleasants, J. R., and Balish, E., The effect of microbial flora, diet, and age on the tumoricidal activity of natural killer cells.J. Leukoc. Biol.,36, 739-750 (1984).
15. Cebra, J. J., Periwal, S. B., Lee, G., Lee, F., and Shroff, K. E., Development and maintenance of the gut-associated lymphoid tissue (GALT): the role of enteric bacteria and viruses, Dev. Immunol.,6(1-2), 13-18 (1998).
16. Matsuzaki, K. and Yokokura, T., Antitumor effect of oral administeration ofLactobacillus caseiin newborn mice.Igaku-no-Ayumi(in Japanese), 150, 745-746 (1989).
17. Blomberg, K., Granberg, C., Hemmila, I., and Lovgren, T., Europium-labeled target cells in an assay of natural killer cell activity. I. A novel nonradioactive method based on time-resolved fluorescence.J. Immunol. Methods.,86, 225-229 (1986).
18. +) release assay to a measurement of human natural killer activity of healthy and patient populations.Immun. Invest.,25, 507-518 (1996).
19. Tada, T. and Okumura, K., Senescence and immunity.Chemistry Today(in Japanese), 11, 40-45 (1984).
20. Shida, K., Makino, K., Morishita, A., Takamizawa, K., Hachimura, S., Ametani, A., Sato, T., Kumagai, Y., and Kaminogawa, S., Lactobacillus caseiinhibits antigen-induced IgE secretion through regulation of cytokine production in murine splenocyte cultures.Int. Arch. Allergy Immunol.,115, 278-287 (1998).
21. Kato, I., Tanaka, K., and Yokokura, T., Lactic acid bacterium potently unduces the production of interleukin-12 and interferon-y by mouce splenocytes.Int. J. Immunopharmacol.,21, 121-131 (1999).
22. Hoffman, G. L. and Pederson, B. K., Exercise and the immune system: a model of the stress response.Immunol. Today,15, 382-387 (1994).
23. Nakachi, K. and Imai, K., Environmental and physiological influences on human natural killer cell activity in relation to good health practices.Jpn. J. Cancer Res.,83, 798-805 (1992).