DNA methylation, ageing and ribosomal genes activity

Biogerontology

Volumn 1, Issue 4, 2000, Pages 357-361

  De Carvalho, C V ^a   Payao S L M ^a   Smith, M D A C ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Ageing; Alzheimer's disease; Dna methylation; Nucleolus Organizer Region; Ribosomal genes

Indexed keywords

AZACITIDINE; RIBOSOME DNA;

ADULT; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; CELL CULTURE; CHROMOSOME 22; DNA METHYLATION; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; RIBOSOME;

ADULT; AGED; AGING; ALZHEIMER DISEASE; AZACITIDINE; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 22; DNA METHYLATION; DNA, RIBOSOMAL; HUMANS; RIBOSOMES; TRANSCRIPTION, GENETIC;

EID: 0034571152     PISSN: 13895729     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Ahuja N, Li Q, Mohan AL, Baylin SB, Issa JPJ (1998) Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 58: 5489-5494
2. Borsatto B and Smith MdeAC (1996) Reduction of the activity of ribossomal genes in age in Down's Syndrome. Gerontology 42: 147-154
3. de Capoa A, Felli MP, Baldin A, Rocchi M, Archidiacono N, Aleixandre C, Miller OJ, Miller DA (1988) Relationship between the number and function of human ribosomal genes. Hum Genet 79: 301-304
4. Ferraro M and Lavia P (1983) Activation of human ribosomal genes by 5-azacytidine. Exp Cell Res 145: 452-457
5. Ferraro M and Lavia P (1985) Differential gene activity visualized on sister chromatids after replication in the presence of 5-azacytidine. Chromosoma 91: 307-312
6. Ferraro M and Prantera G (1988) Human NORs show correlation between transcriptional activity, Dnase I sensitivity, and hypomethylation. Cytogenet Cell Genet 47: 58-61
7. Gasser SM, Paro R, Stewart F, Aasland R (1998) Epigenetic control of transcription. Introduction: the genetics of epigenetics. Cell Mol Life Sci 54: 1-5
8. Glover AB and Leyland-Jones B (1987) Biochemistry of azacytidine: a review. Cancer Treat Rep 71: 959-964
9. Holliday R (1989) A different kind of inheritance. Sci Am 260 (Suppl 16): 40-48
10. Holliday R (1996) DNA Methylation in eukariotics. In: Russo VEA, Martienssen RA and Riggs AD (eds) Epigenetic Mechanisms of Gene Regulation, pp 5-12, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
11. Howell WM and Black DA (1980) Controlled silver-staining of nucleolar organizers regions with a protective colloidal developer: A1-step method. Experimentia 36: 1014-1015
12. Hubbel HR (1985) Silver staning as an indicador of active ribosomal genes. Stain Technol 60: 285
13. Kanungo MS (1994) Genes and aging, pp 216-225. Cambridge University Press, Cambridge
14. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease. Neurology 34: 939-944
15. Moorhead PS, Nowell PS, Mellmann WJ, Battips DM, Hunger-Ford DH (1960) Chromosome preparations of leucocytes cultures from human peripheral blood. Exp Cell Res 20: 613-616
16. Morris JC (1993) The clinical dementia rating (CDR): current version and scoring rules. Neurology 43: 2412-2414
17. Payão SLM, Smith MdeAC, Kormann-Bortolotto MH, Toniolo-Neto J (1994) Investigation of the nucleolar organizer region in Alzheimer's disease. Gerontology 40: 13-17
18. Payão SLM, Bertolucci PHF, Smith MdeAC (1998a) Differential chromosome sensitivity to 5-Azacytidine in Alzheimer's disease. Gerontology 44: 267-271
19. Payão SLM, Smith MdeAC, Winter LMF, Bertolucci PHF (1998b) Ribosomal RNA in Alzheimer's disease and ageing. Mech Ageing Dev 105: 265-272
20. Sanchez O, Escobar JI, Yunis JJ (1973) A simple G banding technique. Lancet II: 269
21. Schmid M, Ott G, Haaf T, Scheres JMC (1985) Evolutionary conservation of fragile sites induced by 5-azadeoxycytidine in man, gorilla and chimpanzee. Hum Genet 71: 342-350
22. Siegel S (1975) Nonparametric Statistics for the Behavioral Sciences. McGraw-Hill, New York
23. Smith MdeAC (1999) Doença de Alzheimer. Rev Bras Psiquiatr 21 (Sup 2): 3-7
24. Sommerville J (1985) Organizing the nucleolus. Nature 318: 410-411