Inhibition of X-ray and doxorubicin-induced apoptosis by butyrolactone I, a CDK-specific inhibitor, in human tumor cells

Journal of Radiation Research

Volumn 41, Issue 4, 2000, Pages 341-348

  Lu, Yanjun ^a,b   Takebe, Hiraku ^a,c   Yagi, Takashi ^a,d  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Shanghai Celstar Bio P   (China)

^c KINKI UNIVERSITY   (Japan)

^d Osaka Prefecture University   (Japan)

Author keywords

Apoptosis; CDK; Doxorubicin; p21; X ray

Indexed keywords

ENZYMES;

BUTYROLACTONES; CELL-CYCLE PROGRESSION; COLORECTAL CARCINOMA; CYCLIN-DEPENDENT KINASE; DNA DAMAGING AGENTS; DOXORUBICIN; HUMAN TUMOR CELLS; INDUCED APOPTOSIS; P21; SPECIFIC INHIBITORS;

CELL DEATH;

ANTINEOPLASTIC ANTIBIOTIC; BUTYROLACTONE I; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; DOXORUBICIN; DRUG DERIVATIVE; ENZYME INHIBITOR; GAMMA BUTYROLACTONE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; X RAY;

4-BUTYROLACTONE; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL CYCLE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DOXORUBICIN; ENZYME INHIBITORS; HUMANS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; X-RAYS;

EID: 0034569792     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.41.341     Document Type: Article

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