Elevated temperatures enhance KCCl activity in sickle cells

Bioelectrochemistry

Volumn 52, Issue 2, 2000, Pages 127-131

  Khan, A ^a   Ellory, J C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

KCCl; Red cells; Sickle; Temperature

Indexed keywords

DEHYDRATION; POTASSIUM COMPOUNDS; THERMAL EFFECTS; UREA;

SICKLE CELLS;

CELLS;

CARRIER PROTEIN; N ETHYLMALEIMIDE; UREA;

ARTICLE; CONTROLLED STUDY; DEHYDRATION; ERYTHROCYTE; HUMAN; HUMAN CELL; POTASSIUM CELL LEVEL; POTASSIUM TRANSPORT; SICKLE CELL; TEMPERATURE;

EID: 0034564475     PISSN: 03024598     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0302-4598(00)00111-2     Document Type: Article

References (15)

1. Determinants of red cell sickling. Effects of varying pH and of increasing intracellular hemoglobin concentration by osmotic shrinkage
2. Volume-dependent and NEM-stimulated K+,Cl- transport is elevated in oxygenated SS, SC and CC human red cells
3. Volume-stimulated, Cl(-)-dependent K+ efflux is highly expressed in young human red cells containing normal hemoglobin or HbS
4. Effects of urea and oxygen tension on K flux in sickle cells
5. Inhibition of K+ efflux and dehydration of sickle cells by [(dihydroindenyl)oxy]alkanoic acid: an inhibitor of the K+ Cl- cotransport system
6. Deoxygenation of sickle red blood cells stimulates KCl cotransport without affecting Na+/H+ exchange
7. Oxidative activation of K-Cl cotransport by diamide in erythrocytes from humans with red cell disorders, and from several other mammalian species
8. Rate of activation and deactivation of K:Cl cotransport by changes in cell volume in hemoglobin SS, CC and AA red cells
9. Volume-sensitive cation fluxes in mammalian red cells
10. Kinetics and mechanism of deoxyhemoglobin S gelation: a new approach to understanding sickle cell disease
11. The temperature dependence of passive potassium permeability in mammalian erythrocytes
12. Kinetics of activation and inactivation of swelling-stimulated K+/Cl- transport. The volume-sensitive parameter is the rate constant for inactivation
13. Thiol-dependent passive K/Cl transport in sheep red cells: I. Dependence on chloride and external ions
14. Okadaic acid inhibition of KCl cotransport. Evidence that protein dephosphorylation is necessary for activation of transport by either cell swelling or N-ethylmaleimide
15. Urea activation of K-Cl transport in human erythrocytes