A multiple transgenic mouse model with a partially humanized activation pathway for helper T cell responses

Journal of Immunological Methods

Volumn 246, Issue 1-2, 2000, Pages 37-50

  Laub, Rüdiger ^a,b   Dorsch, Martina ^c   Meyer, Dorothea ^a   Ermann, Jörg ^a   Hedrich, Hans Jürgen ^c   Emmrich, Frank ^b  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Human CD4; In vivo animal models; T lymphocyte; Transgenic knockout

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; HLA DR17 ANTIGEN; HLA DR3 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; TETANUS TOXOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; HUMAN; KNOCKOUT MOUSE; LEUKOCYTE; LYMPH NODE; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE ACTIVATION; THYMUS; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD4; ANTIGENS, CD8; CROSSES, GENETIC; DOWN-REGULATION; FEMALE; GENE EXPRESSION; HLA-DR3 ANTIGEN; HUMANS; LEUKOCYTES, MONONUCLEAR; LYMPHATIC SYSTEM; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, ANIMAL; PHENOTYPE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TETANUS TOXOID; TRANSGENES;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0034564117     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(00)00288-X     Document Type: Article

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