Effects of low-dose aspirin on uterine and fetal blood flow during pregnancy: Results of a randomized, placebo-controlled, double-blind trial

Ultrasound in Obstetrics and Gynecology

Volumn 15, Issue 1, 2000, Pages 19-27

  Grab, D ^a   Paulus, W E ^a   Erdmann, M ^a   Terinde, R ^a   Oberhoffer, R ^a   Lang, D ^a   Muche, R ^a   Kreienberg, R ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Doppler sonography; Ductus arteriosus; Fetal blood flow; Low dose aspirin; Uteroplacental blood flow

Indexed keywords

ACETYLSALICYLIC ACID; PLACEBO;

ADULT; AORTA; ARTICLE; BLOOD FLOW VELOCITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DUCTUS ARTERIOSUS; FEMALE; FETUS; FETUS CIRCULATION; GESTATIONAL AGE; HEART ATRIOVENTRICULAR VALVE; HEMODYNAMICS; HUMAN; MIDDLE CEREBRAL ARTERY; PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; UTERINE ARTERY; UTERUS BLOOD FLOW;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BLOOD FLOW VELOCITY; CYCLOOXYGENASE INHIBITORS; DOUBLE-BLIND METHOD; FEMALE; FETAL GROWTH RETARDATION; FETUS; GESTATIONAL AGE; HUMANS; LONGITUDINAL STUDIES; PLACENTAL CIRCULATION; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PREGNANCY TRIMESTER, THIRD; PREGNANCY, HIGH-RISK; ULTRASONOGRAPHY, DOPPLER; ULTRASONOGRAPHY, PRENATAL;

EID: 0034546790     PISSN: 09607692     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-0705.2000.00009.x     Document Type: Article

References (30)

1. Aspirin for the treatment of recurrent toxaemia
2. The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies
3. Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy induced hypertension
4. Prevention of pre-eclampsia by early antiplatelet therapy
5. Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae
6. Doppler ultrasound and aspirin in recognition and prevention of pregnancy-induced hypertension
7. Prevention of fetal growth restriction with low-dose aspirin: Findings of the EPREDA trial
8. Low-dose aspirin in prevention and treatment of intrauterine growth restriction and pregnancy-induced hypertension
9. A randomized trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women
10. Randomized trial of low-dose aspirin for the prevention of maternal and fetal complications in high risk pregnant women
11. Low-dose aspirin to prevent pre-eclampsia in women at high risk
12. The effect of low-dose aspirin on umbilical artery Doppler measurements
13. Effect on fetal circulation of low-dose aspirin for prevention and treatment of pre-eclampsia and intrauterine growth retardation
14. Transfer of aspirin across the perfused human placental cotyledon
15. Detection and quantitation of constriction of the fetal ductus arteriosus by Doppler echocardiography
16. Indomethacin in the treatment of premature labor: Effects on the ductus arteriosus
17. Incidence of indomethacin-induced human fetal ductal constriction
18. The effect of indomethacin tocolysis on fetal ductus arteriosus constriction with advancing gestational age
19. Effects of maternal ingestion of low-dose aspirin on the fetal cardiovascular system
20. Cardiac function in fetuses and newborns exposed to low-dose aspirin during pregnancy
21. The fetal Doppler echocardiography
22. Fetal ductal constriction during indomethacin therapy for the treatment of premature labor and polyhydramnios: A new classification
23. Low-dose aspirin in the prevention of pre-eclampsia and fetal growth restriction: Rationale, mechanisms, and clinical trials
24. Uteroplacental Doppler and aspirin therapy in the prediction and prevention of pregnancy complications
25. Doppler ultrasound of the uterine artery: The importance of bilateral notching in the prediction of pre-eclampsia, placental abruption or delivery of a small-for-gestational-age baby
26. Prediction of pre-eclampsia by abnormal uterine Doppler ultrasound and modification by aspirin
27. A randomized controlled trial of aspirin in patients with abnormal uterine artery blood flow
28. Continuous wave Doppler velocimetry of uterine and umbilical blood flow in the second and third trimester of pregnancy: Normal values
29. Doppler assessment of the pulsatility index of the middle cerebral artery during constriction of the fetal ductus arteriosus after indomethacin therapy
30. Aspirin and prevention of pre-eclampsia